Fructose-1,6-bisphosphate and N-acetylcysteine attenuate the formation of advanced oxidation protein products, a new class of inflammatory mediators, in vitro

Inflammation

Volumn 35, Issue 6, 2012, Pages 1786-1792

  Bochi, Guilherme Vargas ^a   Torbitz, Vanessa Dorneles ^a   Cargnin, Lara Peruzzolo ^a   Sangoi, Manuela Borges ^a   Christ Vianna Santos, Roberto ^b   Gomes, Patrícia ^c   Moresco, Rafael Noal ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b Núcleo Integrado de Desenvolvimento em Análises Laboratoriais NIDAL   (Brazil)

^c CENTRO UNIVERSITÁRIO FRANCISCANO   (Brazil)

Author keywords

Advanced oxidation protein products; Fructose 1,6 bisphosphate; Inflammation; N acetylcysteine; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ADVANCED OXIDATION PROTEIN PRODUCT; FRUCTOSE 1,6 BISPHOSPHATE; HUMAN SERUM ALBUMIN; HYPOCHLOROUS ACID;

ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; IN VITRO STUDY;

ACETYLCYSTEINE; ADVANCED OXIDATION PROTEIN PRODUCTS; BIOLOGICAL MARKERS; FRUCTOSEDIPHOSPHATES; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SERUM ALBUMIN;

EID: 84872186173     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-012-9498-6     Document Type: Article

References (58)

1. Hancock, J.T., R. Desikan, and S.J. Neill. 2001. Role of reactive oxygen species in cell signalling pathway. Biochemical Society Transactions 29: 345-350. (Pubitemid 32587530)
2. Asaba, K., A. Tojo, M.L. Onozato, A. Goto, M.T. Quinn, T. Fujita, and C.S. Wilcox. 2005. Effects of NADPH oxidase inhibitor in diabetic nephropathy. Kidney International 67: 1890-1898. (Pubitemid 40577724)
3. Halliwell, B. 1992. Reactive oxygen species and the central nervous system. Journal of Neurochemistry 59: 1609-1623.
4. Dalle-Donne, I., R. Rossi, R. Colombo, D. Giustarini, and A. Milzani. 2006. Biomarkers of oxidative damage in human disease. Clinical Chemistry 52: 601-623.
5. Miyata, T., and C.Y. de Strihou. 2010. Diabetic nephropathy: a disorder of oxygen metabolism? Nature Reviews Nephrology 6: 83-95.
6. Shacter, E. 2000. Protein oxidative damage. Methods in Enzymology 319: 428-436. (Pubitemid 30448062)
7. Witko-Sarsat, V., M. Friedlander, C. Capeillère-Blandin, T. Nguyen-Khoa, A.T. Nguyen, J. Zingraff, P. Jungers, and B. Descamps-Latscha. 1996. Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney International 49: 1304-1313. (Pubitemid 26166404)
8. Shi, X.Y., F.F. Hou, H.X. Niu, G.B. Wang, D. Xie, Z.J. Guo, Z.M. Zhou, F. Yang, J.W. Tian, and X. Zhang. 2008. Advanced oxidation protein products promote inflammation in diabetic kidney through activation of renal nicotinamide adenine dinucleotide phosphate oxidase. Endocrinology 149: 1829-1839. (Pubitemid 351468323)
9. Zhou, L.L., F.F. Hou, G.B. Wang, F. Yang, D. Xie, Y.P. Wang, and J.W. Tian. 2009. Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanisms. Kidney International 76: 1148-1160.
10. Hanasand, M., R. Omdal, K.B. Norheim, L.G. Gøransson, C. Brede, and G. Jonsson. 2012. Improved detection of advanced oxidation protein products in plasma. Clinica Chimica Acta 413: 901-906.
11. Kalousová, M., J. Skrha, and T. Zima. 2002. Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus. Physiological Research 51: 597-604. (Pubitemid 36168668)
12. Martín-Gallán, P., A. Carrascosa, M. Gussinyé, and C. Domínguez. 2003. Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications. Free Radical Biology & Medicine 34: 1563-1574. (Pubitemid 36638716)
13. Tabak, O., R. Gelisgen, H. Erman, F. Erdenen, C. Muderrisoglu, H. Aral, and H. Uzun. 2011. Oxidative lipid, protein, and DNA damage as oxidative stress markers in vascular complications of diabetes mellitus. Clinical and Investigative Medicine 34: 163-171.
14. Chen, S., L. Liu, X. Sun, Y. Liu, and T. Son. 2005. Captopril restores endothelium-dependent relaxation induced by advanced oxidation protein products in rat aorta. Journal of Cardiovascular Pharmacology 46: 803-809. (Pubitemid 44378253)
15. Atabek, M.E., M. Keskin, C. Yazici, M. Kendirci, N. Hatipoglu, E. Koklu, and S. Kurtoglu. 2006. Protein oxidation in obesity and insulin resistance. European Journal of Pediatrics 165: 753-756. (Pubitemid 44440512)
16. Gröne, H.J., E.F. Gröne, and E. Malle. 2002. Immunohistochemical detection of hypochlorite-modified proteins in glomeruli of human membranous glomerulonephritis. Laboratory Investigation 82: 5-14. (Pubitemid 34072641)
17. Kaneda, H., J. Taguchi, K. Ogasawara, T. Aizawa, and M. Ohno. 2002. Increased level of advanced oxidation protein products in patients with coronary artery disease. Atherosclerosis 162: 221-225. (Pubitemid 34327362)
18. Witko-Sarsat, V., T. Nguyen Khoa, P. Jungers, T. Drüeke, and B. Descamps-Latscha. 1998. Advanced oxidation protein products: oxidative stress markers and mediators of inflammation in uremia. Advances in Nephrology from the Necker Hospital 28: 321-341.
19. Capeillère-Blandin, C., V. Gausson, B. Descamps-Latscha, and V. Witko-Sarsat. 2004. Biochemical and spectrophotometric significance of advanced oxidized protein products. Biochimica et Biophysica Acta 1689: 91-102. (Pubitemid 38766144)
20. Descamps-Latscha, B., and V. Witko-Sarsat. 2001. Importance of oxidatively modified proteins in chronic renal failure. Kidney International. Supplement 78: 108-113.
21. Witko-Sarsat, V., V. Gausson, A.T. Nguyen, M. Touam, T. Drüeke, F. Santangelo, and B. Descamps-Latscha. 2003. AOPP-induced activation of human neutrophil and monocyte oxidative metabolism: a potential target for N-acetylcysteine treatment in dialysis patients. Kidney International 64: 82-91. (Pubitemid 36714160)
22. 2+ and phospholipase C. Brain Research 958: 43-51. (Pubitemid 35441212)
23. De Oliveira, J.R., J.L. Rosa, S. Ambrosio, and R. Bartrons. 1992. Effect of galactosamine on hepatic carbohydrate metabolism: protective role of fructose 1,6-bisphosphate. Hepatology 15: 1147-1153.
24. Nunes, F.B., C.M. Graziottin, J.C. Alves Filho, A. Lunardelli, M.G. Pires, P.H. Wächter, and J.R. De Oliveira. 2003. An assessment of fructose-1,6-bisphosphate as an antimicrobial and anti-inflammatory agent in sepsis. Pharmacological Research 47: 35-41. (Pubitemid 36259620)
25. Cotgreave, I.A. 1997. N-acetylcysteine: pharmacological considerations and experimental and clinical applications. Advances in Pharmacology 38: 205-227.
26. Nascimento, M.M., M.E. Suliman, M. Silva, T. Chinaglia, J. Marchioro, S.Y. Hayashi, M.C. Riella, B. Lindholm, and B. Anderstam. 2010. Effect of oral N-acetylcysteine treatment on plasma inflammatory and oxidative stress markers in peritoneal dialysis patients: a placebo-controlled study. Peritoneal Dialysis International 30: 336-342.
27. Morris, J.C. 1966. The acid ionization constant of HOCl from 5 to 35. The Journal of Physical Chemistry 70: 3798-3805.
28. Iwao, Y., M. Anraku, M. Hiraike, K. Kawai, K. Nakajou, T. Kai, A. Suenaga, and M. Otagiri. 2006. The structural and pharmacokinetic properties of oxidized human serum albumin, advanced oxidation protein products (AOPP). Drug Metabolism and Pharmacokinetics 21: 140-146.
29. Hawkins, C.L., D.I. Pattison, and M.J. Davies. 2003. Hypochloriteinduced oxidation of amino acids, peptides and proteins. Amino Acids 25: 259-274. (Pubitemid 38041264)
30. Hazell, L.J., J.J. van den Berg, and R. Stocker. 1994. Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation. The Biochemical Journal 302: 297-304. (Pubitemid 24256368)
31. Kettle, A.J. 1996. Neutrophils convert tyrosyl residues in albumin to chlorotyrosine. FEBS Letters 379: 103-106. (Pubitemid 26033928)
32. Yang, C.Y., Z.W. Gu, H.X. Yang, M. Yang, A.M. Gotto, and C.V. Smith. 1997. Oxidative modifications of apoB-100 by exposure of low density lipoproteins to HOCL in vitro. Free Radical Biology & Medicine 23: 82-89. (Pubitemid 27217011)
33. Thomas, E.L., M.B. Grisham, and M.M. Jefferson. 1986. Preparation and characterization of chloramines. Methods in Enzymology 132: 569-585. (Pubitemid 17233604)
34. Mera, K., R. Nagai, N. Haraguchi, Y. Fujiwara, T. Araki, N. Sakata, and M. Otagiri. 2007. Hypochlorous acid generates N epsilon-(carboxymethyl)lysine from Amadori products. Free Radical Research 41: 713-718. (Pubitemid 46845592)
35. Fu, S., H. Wang, M. Davies, and R. Dean. 2000. Reactions of hypochlorous acid with tyrosine and peptidyl-tyrosyl residues give dichlorinated and aldehydic products in addition to 3-chlorotyrosine. The Journal of Biological Chemistry 75: 10851-10858. (Pubitemid 30212717)
36. Himmelfarb, J., E. McMonagle, and E. McMenamin. 2000. Plasma protein thiol oxidation and carbonyl formation in chronic renal failure. Kidney International 58: 2571-2578.
37. Mera, K., M. Anraku, K. Kitamura, K. Nakajou, T. Maruyama, and M. Otagiri. 2005. The structure and function of oxidized albumin in hemodialysis patients: its role in elevated oxidative stress via neutrophil burst. Biochemical and Biophysical Research Communications 334: 1322-1328. (Pubitemid 41074719)
38. Peskin, A.V., and C.C. Winterbourn. 2001. Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine and ascorbate. Free Radical Biology & Medicine 30: 572-579. (Pubitemid 32162964)
39. Alva, N., T. Carbonell, T. Roig, J. Bermúdez, and J. Palomeque. 2011. Fructose 1,6 biphosphate administration to rats prevents metabolic acidosis and oxidative stress induced by deep hypothermia and rewarming. European Journal of Pharmacology 659: 259-264.
40. Bajić, A., J. Zakrzewska, D. Godjevac, P. Andjus, D.R. Jones, M. Spasić, and I. Spasojević. 2011. Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions. Carbohydrate Research 346: 416-420.
41. McGilvery, R.W. 1953. Cyclohexylammonium fructose-1, 6-diphosphates. The Journal of Biological Chemistry 200: 835-838.
42. Song, Y., and M.R. Gunner. 2009. Using multiconformation continuum electrostatics to compare chloride binding motifs in alpha-amylase, human serum albumin and Omp32. Journal of Molecular Biology 387: 840-856.
43. Santos, R.C., R.N. Moresco, M.A. Peña Rico, A.R. Susperregui, J.L. Rosa, R. Bartrons, F. Ventura, D.N. Mário, S.H. Alves, E. Tatsch, H. Kober, R.O. de Mello, P. Scherer, H.B. Dias, and J.R. de Oliveira. 2012. Fructose-1,6-bisphosphate reduces the mortality in Candida albicans bloodstream infection and prevents the septic-induced platelet decrease. Inflammation. doi:10.1007/s10753-012-9436-7.
44. de Mello, R.O., A. Lunardelli, E. Caberlon, C.M. de Moraes, R. Christ Vianna Santos, V.L. da Costa, G.V. da Silva, P. da Silva Scherer, L.E. Buaes, D.A. da Silva Melo, M.V. Donadio, F.B. Nunes, and J.R. de Oliveira. 2011. Effect of N-acetylcysteine and fructose-1,6-bisphosphate in the treatment of experimental sepsis. Inflammation 34: 539-50.
45. Lian, X.Y., F.A. Khan, and J.L. Stringer. 2007. Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats. The Journal of Neuroscience 27: 12007-12011. (Pubitemid 350072086)
46. Moresco, R.N., R.C. Santos, J.C. Alves Filho, A.A. Cunha, C. Dos Reis, C.L. Reichel, and J.R. De Oliveira. 2004. Protective effect of fructose-1,6-bisphosphate in the cold storage solution for liver preservation in rat hepatic transplantation. Transplantation Proceedings 36: 1261-1264. (Pubitemid 38902952)
47. Xu, M., D.Z. Dai, Q. Zhang, Y.S. Cheng, and Y. Dai. 2010. Upregulated NADPH oxidase contributes to diabetic testicular complication and is relieved by strontium fructose 1,6-diphosphate. Experimental and Clinical Endocrinology & Diabetes 118: 459-465.
48. Gámez, A., N. Alva, T. Roig, J. Bermúdez, and T. Carbonell. 2008. Beneficial effects of fructose 1,6-biphosphate on hypothermiainduced reactive oxygen species injury in rats. European Journal of Pharmacology 590: 115-119.
49. Ahn, S.M., J.S. Hwang, and S.H. Lee. 2007. Fructose 1,6-diphosphate alleviates UV-induced oxidative skin damage in hairless mice. Biological and Pharmaceutical Bulletin 30: 692-697.
50. Calafell, R., J. Boada, A.F. Santidrian, J. Gil, T. Roig, J.C. Perales, and J. Bermudez. 2009. Fructose 1,6-bisphosphate reduced TNFalpha-induced apoptosis in galactosamine sensitized rat hepatocytes through activation of nitric oxide and cGMP production. European Journal of Pharmacology 610: 128-133.
51. Rogido, M., I. Husson, C. Bonnier, M.C. Lallemand, C. Mérienne, G.A. Gregory, A. Sola, and P. Gressens. 2003. Fructose-1,6-biphosphate prevents excitotoxic neuronal cell death in the neonatal mouse brain. Brain Research 140: 287-297. (Pubitemid 36173985)
52. Lazzarino, G., B. Tavazzi, D. Di Pierro, and B. Giardina. 1992. Ischemia and reperfusion: effect of fructose-1,6-bisphosphate. Free Radical Research Communications 16: 325-339.
53. Akimitsu, T., J.A. White, D.L. Carden, D.C. Gute, and R.J. Korthuis. 1995. Fructose-1,6-diphosphate or adenosine attenuate leukocyte adherence in postischemic skeletal muscle. The American Journal of Physiology 269: 1743-1751.
54. Ahn, S.M., H.Y. Yoon, B.G. Lee, K.C. Park, J.H. Chung, C.H. Moon, and S.H. Lee. 2002. Fructose-1,6-diphosphate attenuates prostaglandin E2 production and cyclo-oxygenase-2 expression in UVB-irradiated HaCaT keratinocytes. British Journal of Pharmacology 137: 497-503. (Pubitemid 35221903)
55. Lopes, R.P., A. Lunardelli, T. Preissler, C.E. Leite, J.C. Alves-Filho, F.B. Nunes, J.R. de Oliveira, and M.E. Bauer. 2006. The effects of fructose-1,6-bisphosphate and dexamethasone on acute inflammation and T-cell proliferation. Inflammation Research 55: 354-358. (Pubitemid 44411342)
56. Aruoma, O.I., B. Halliwell, B.M. Hoey, and J. Butler. 1989. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radical Biology & Medicine 6: 593-597. (Pubitemid 19147809)
57. Fishbane, S. 2008. N-acetylcysteine in the prevention of contrastinduced nephropathy. Clinical Journal of the American Society of Nephrology 3: 281-287.
58. Holt, S., R. Marley, B. Fernando, D. Harry, R. Anand, D. Goodier, and K. Moore. 1999. Acute cholestasis-induced renal failure: effects of antioxidants and ligands for the thromboxane A2 receptor. Kidney International 55: 271-277. (Pubitemid 29004259)