Dopamine stimulates propagation of Toxoplasma gondii tachyzoites in human fibroblast and primary neonatal rat astrocyte cell cultures

Journal of Parasitology

Volumn 98, Issue 6, 2012, Pages 1296-1299

  Strobl, Jeannine S ^a   Goodwin, David G ^b   Rzigalinski, Beverly A ^b,c   Lindsay, David S ^b  

^a Virginia Polytechnic Institute and State University   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^c EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; SULPIRIDE;

ANTIBODY; BRAIN; CORRELATION; CYTOLOGY; PARASITIC DISEASE; PARASITOLOGY; PSYCHOLOGY; RODENT;

ANIMAL CELL; ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MONOLAYER CULTURE; NEWBORN; NONHUMAN; TACHYZOITE; TOXOPLASMA GONDII;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELLS, CULTURED; DOPAMINE; DOPAMINE ANTAGONISTS; FIBROBLASTS; HUMANS; RATS; RATS, SPRAGUE-DAWLEY; SCHIZOPHRENIA; SYMPATHOMIMETICS; TOXOPLASMA; TOXOPLASMOSIS, CEREBRAL;

RATTUS; TOXOPLASMA GONDII;

EID: 84872182295     PISSN: 00223395     EISSN: 19372345     Source Type: Journal    
DOI: 10.1645/GE-2760.1     Document Type: Article

References (34)

1. CARTER, C. J. 2009. Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: Cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii. Schizophrenia Bulletin 35: 1163-1182.
2. CHANDRAMOHANADAS, R., P. H. DAVIS, D. P. BEITING, M. B. HARBUT, C. DARLING, G. VELMOUROUGANE, M. Y. LEE, P. A. GREER, D. S. ROOS, D. C. GRANBAUM ET AL. 2009. Apicomplexan parasites co-opt host calpain and facilitate their escape from infected cells. Science 324: 794-797.
3. CROOKS, P. A., X. O. BREAKEFIELD, C.H. SULENS, C. M. CASTIGLIONE, AND J. K. COWARD. 1978. Extensive conjugation of dopamine (3,4- dihydroxyphenethylamine) metabolites in cultured human skin fibroblasts and rat hepatoma cells. Biochemical Journal 176: 187-196. (Pubitemid 9060527)
4. FEKADU, A., T. SHIBRE, AND A. J. CLEARE. 2010. Toxoplasmosis as a cause for behaviour disorders-Overview of evidence and mechanisms. Folia Parasitologica (Praha) 57: 105-113.
5. FLEGR, J., AND I. HRDY. 1994. Influence of chronic toxoplasmosis on some human personality factors. Folia Parasitologica (Praha) 41: 122-126. (Pubitemid 2112745)
6. -, M. PREISS, J. KLOSE, J. HAVLÍCEK, M. VITÁKOVÁ, AND P. KODYM. 2003. Decreased level of psychobiological factor novelty seeking and lower intelligence in men latently infected with the protozoan parasite Toxoplasma gondii dopamine, a missing link between schizophrenia and toxoplasmosis? Biological Psychology 63: 253-268. (Pubitemid 36802307)
7. GASKELL, E. A., J. E. SMITH, J. W. PINNEY, D. R. WESTHEAD, AND G. A. MCCONKEY. 2009. A unique dual activity amino acid hydroxylase in Toxoplasma gondii. PLoS ONE 4: e4801.
8. GERIN, C. G., K. SMITH, S. HILL, AND J. C.MADUEKE. 2011. Motor activity affects dopaminergic and noradrenergic systems of the dorsal horn of the rat lumbar spinal cord. Synapse 65: 1282-1288.
9. GOODWIN, D. G., T. C. HRUBEC, B. G. KLEIN, J. S. STROBL, S. R. WERRE, Q. HAN, A.M. ZAJAC, AND D. S. LINDSAY. 2012. Congenital infection of mice with Toxoplasma gondii induces minimal change in behavior and no change in neurotransmitter concentrations. Journal of Parasitology 98: 706-712.
10. GROSHONG, R., D. A. GIBSON, AND R. J. BALDESSARINI. 1977. MAO activity in cultured human skin fibroblasts. Clinical Chimica Acta 80: 113-120. (Pubitemid 8187220)
11. HAY, J., P. P. AITKEN, AND D. I. GRAHAM. 1984. Toxoplasma infection and response to novelty in mice. Zeitschrift für Parasitenkunde 70: 575-588. (Pubitemid 14068040)
12. HENRIQUEZ, S. A., R. BRETT, J. ALEXANDER, J. PRATT, AND C. W. ROBERTS. 2009. Neuropsychiatric disease and Toxoplasma gondii infection. Neuroimmunomodulation 16: 122-133.
13. HERMES, G., J. W. AJIOKA, K. A. KELLY, E.MUI, F. ROBERTS, K. KASZA, T. MAYR, M. J.KIRISITS, R. WOLLMANN, D. J. FERGUSON ET AL. 2008. Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection. Journal of Neuroinflammation 5: 48.
14. HUTCHINSON, W. M., M. BRADLEY, W. M. CHEYNE, B. W. WELLS, AND J. HAY. 1980. Behavioural abnormalities in Toxoplasma-infected mice. Annals of Tropical Medicine and Parasitology 74: 337-345. (Pubitemid 10000364)
15. LOURIDO, S., J. SHUMAN, C. ZHANG, K. M. SHOKAT, R. HUI, AND L. D. SIBLEY. 2010. Calcium-dependent PK1 is an essential regulator of exocytosis in toxoplasma. Nature 465: 359-362.
16. MANAKOVA, S., K. A. PUTTONEN, A.RAASMAJA, AND P. T.MANAISTO. 2004. The roles of dopamine transporter and Bcl-2 protein in the protection of CV1-P cells from 6-hydroxydopamine-induced toxicity. Toxicology Letters 154: 117-123. (Pubitemid 39314595)
17. MURATA, M., N. KATAGIRI, K. ISHIDA, K. ABE, M. ISHIKAWA, I. UTSUNOMIYA, K. HOSHI, K. MIYAMOTO, AND K. TOGUCHI. 2009. Effect of b-phenylethylamine on extracellular concentrations of dopamine in the nucleus accumbens and prefrontal cortex. Brain Research 1269: 40-46.
18. NAGAMUNE, K., L. M. HICKS, B. FUX, F. BROSSIER, E.N. CHINI, AND L. D. SIBLEY. 2008. Abscissic acid controls calcium-dependent egress and development in Toxoplasma gondii. Nature 45: 207-210.
19. NOVOTNÁ, M., J. HANUSOVA, J. KLOSE, M. PREISS, J. HAVLICEK, K. ROUBALOVÁ, AND J. FLEGR. 2005. Probable neuroimmunological link between Toxoplasma and cytomegalovirus infections and personality changes in the human host. BMC Infectious Diseases 5: 54. http://www.biomedcentral.com/1471-2334/5/ 54.
20. PRANDOVSZKY, E., E. GASKELL, H. MARTIN, J. P. DUBEY, J. P. WEBSTER, AND G. A. MCCONKEY. 2011. The neurotropic parasite Toxoplasma gondii increases dopamine metabolism. PLoS ONE 6: e23866.
21. REGIER, D. A., W. E. NARROW, D. S. RAE, R. W. MANDERSCHEID, B. Z. LOCKE, AND F. K. GOODWIN. 1993. The de facto US mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. Archives of General Psychiatry 50: 85-94. (Pubitemid 23059313)
22. +2 signals of astrocytes are modulated by the NAD(+)/NADH redox state. Journal of Neurochemistry 120: 1014-1025.
23. RZIGALINSKI, B. A., K. A. WILLOUGHBY, S. HOFFMAN, J. R. FALCK, AND E. F. ELLIS. 1999. Calcium influx factor: Further evidence it is 5,6- epoxyeicosatrienoic acid. Journal of Biological Chemistry 274: 175-182. (Pubitemid 29035046)
24. SKALLOVÁ, A., M. NOVOTNÁ, P. KOLBEKOVÁ, Z. GASOVÁ, V. VESELY, M. SECHOVSKÁ, AND J. FLEGR. 2005. Decreased level of novelty seeking in blood donors infected with Toxoplasma. Neurological and Endocrinological Letters 26: 480-486. (Pubitemid 43013718)
25. SMYTHIES, J. 2000. Role of free radicals in the brain in health and disease in relation to synaptic plasticity. In Free radicals in brain pathophysiology, Chapter 1, G. Poli, E. Cadenoas, and L. Packer (eds.). Marcel Dekker, Inc., New York, New York, p. 1-16.
26. STEINER, J., B. BOGERTS, Z. SARNYAI, M. WALTER, T. GOS, H. G. BERNSTEIN, AND A. M. MYINT. 2012. Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood-brain barrier integrity. World Journal of Biological Psychiatry 13: 482-492.
27. STIBBS, H. H. 1985. Changes in brain concentrations of catecholamines and indoleamines in Toxoplasma gondii infected mice. Annals of Tropical Medicine and Parasitology 79: 153-157. (Pubitemid 16160369)
28. STROBL, J. S., M. CASSELL, S. M. MITCHELL, C. M. REILLY, AND D. S. LINDSAY. 2007. Scriptaid and suberoylanilidehydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. Journal of Parasitology 93: 694-700. (Pubitemid 47036095)
29. TANAHASHI, S., S. YAMAMURA, M. NAKAGAWA, E. MOTOMURA, AND M. OKADA. 2012. Clozapine, but not haloperidol, enhances glial D-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes. British Journal of Pharmacology 165: 1543-1555.
30. TANG, L., R. D. TODD, A. HELLER, AND K. L. O'MALLEY. 1994. Pharmacological and functional characterization of D2, D3, and D4 dopamine receptors in fibroblasts and dopaminergic cell lines. Journal of Pharmacology and Experimental Therapeutics 268: 495-502. (Pubitemid 24039127)
31. VAN ROSSUM, J. 1967. The significance of dopamine receptor blockade for the action of neuroleptic drugs. In Proceedings of the 5th Collegium International Neuro-Psychopharmacologicum, H. Brill, J. Cole, P. Deniker, H. Hippius, and P. Bradley (eds.). Excerpta Medica Foundation, Washington, D.C, p. 321-329.
32. ++ signaling in astrocytes through ROS generated by monoamine oxidase. Journal of Biological Chemistry 285: 25018-25023.
33. WEBSTER, J. P. 2007. The effect of Toxoplasma gondii on animal behavior: Playing cat and mouse. Schizophrenia Bulletin 33: 752-756. (Pubitemid 47343711)
34. YOLKEN, R. H., F. B. DICKERSON, AND E. F. TORREY. 2009. Toxoplasma and schizophrenia. Parasite Immunology 31: 706-715.