Reduction of infectious bursal disease virus replication by shRNAs targeting the VP1 and VP2 genes driven by chicken U6 promoter

Veterinary Microbiology

Volumn 162, Issue 1, 2013, Pages 44-52

  Ouyang, Wei ^a   Ma, Jin rong ^a   Wang, Yong qiang ^b   Qin, Li ting ^b   Jiang, Jie yuan ^a   Fan, Hong jie ^c   Wang, Xiao mei ^b   Wang, Yong shan ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c NANJING AGRICULTURAL UNIVERSITY   (China)

Author keywords

Chicken U6 promoter; Infectious bursal disease virus; RNA interference; Short hairpin RNA

Indexed keywords

MESSENGER RNA; PROTEIN VP1; PROTEIN VP2; SHORT HAIRPIN RNA;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; EMBRYO; EMBRYO DEVELOPMENT; FETUS MEMBRANE; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; INFECTIOUS BURSAL DISEASE; INFECTIOUS BURSAL DISEASE VIRUS; MORTALITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; RECOMBINANT PLASMID; SURVIVAL; TISSUE CULTURE; VIRUS GENE; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; BASE SEQUENCE; CHICK EMBRYO; CHICKENS; GENETIC THERAPY; GENETIC VECTORS; HUMANS; INFECTIOUS BURSAL DISEASE VIRUS; PLASMIDS; POULTRY DISEASES; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; SPECIFIC PATHOGEN-FREE ORGANISMS; TRANSFECTION; VIRAL STRUCTURAL PROTEINS; VIRUS REPLICATION;

GALLUS GALLUS; INFECTIOUS BURSAL DISEASE VIRUS;

EID: 84872173387     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2012.08.012     Document Type: Article

References (28)

1. Achazi K., Patel P., Paliwal R., Radonić A., Niedrig M., Donoso-Mantke O. RNA interference inhibits replication of tick-borne encephalitis virus in vitro. Antiviral Res. 2012, 93:94-100.
2. Bosher J.M., Labouesse M. RNA interference: genetic wand and genetic watchdog. Nat. Cell Biol. 2000, 2:E31-E36.
3. Cui Z.Z., Sun S.H., Shan Z.F., Jiang Y.W., Jin W.J. Pathogenicity of a very virulent strain GX8/99 of infectious bursal disease virus. Chin. J. Virol. 2002, 18:162-166.
4. Dai F., Yusuf F., Farjah G.H., Brand-Saberi B. RNAi-induced targeted silencing of developmental control genes during chicken embryogenesis. Dev. Biol. 2005, 285:80-90.
5. Darniot M., Schildgen V., Schildgen O., Sproat B., Kleines M., Ditt V., Pitoiset C., Pothier P., Manoha C. RNA interference in vitro and in vivo using DsiRNA targeting the nucleocapsid N mRNA of human metapneumovirus. Antiviral Res. 2012, 93:364-373.
6. Das A.T., Brummelkamp T.R., Westerhout E.M., Vink M., Madiredjo M., Bernards R., Berkhout B. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 2004, 78:2601-2605.
7. Das R.M., Van Hateren N.J., Howell G.R., Farrell E.R., Bangs F.K., Porteous V.C., Manning E.M., McGrew M.J., Ohyama K., Sacco M.A., Halley P.A., Sang H.M., Storey K.G., Placzek M., Tickle C., Nair V.K., Wilson S.A. A robust system for RNA interference in the chicken using a modified microRNA operon. Dev. Biol. 2006, 294:554-563.
8. Ergünay K. RNA interference: mechanism and applications. Mikrobiyol. Bul. 2004, 38:285-294.
9. Fernández-Arias A., Martínez S., Rodríguez J.F. The major antigenic protein of infectious bursal disease virus, VP2, is an apoptotic inducer. J. Virol. 1997, 71:8014-8018.
10. Ferreira H.L., Spilki F.R., de Almeida R.S., Santos M.M., Arns C.W. Inhibition of avian metapneumovirus (AMPV) replication by RNA interference targeting nucleoprotein gene (N) in cultured cells. Antiviral Res. 2007, 74:77-81.
11. Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
12. Gao Y., Liu W., Gao H., Qi X., Lin H., Wang X., Shen R. Effective inhibition of infectious bursal disease virus replication in vitro by DNA vector-based RNA interference. Antiviral Res. 2008, 79:87-94.
13. Gitlin L., Stone J.K., Andino R. Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches. J. Virol. 2005, 79:1027-1035.
14. Hinton T.M., Doran T.J. Inhibition of chicken anaemia virus replication using multiple short-hairpin RNAs. Antiviral Res. 2008, 80:143-149.
15. Kim S.M., Lee K.N., Lee S.J., Ko Y.J., Lee H.S., Kweon C.H., Kim H.S., Park J.H. Multiple shRNAs driven by U6 and CMV promoter enhances efficiency of antiviral effects against foot-and-mouth disease virus. Antiviral Res. 2010, 87:307-317.
16. Kneidinger D., Ibrisimovic M., Lion T., Klein R. Inhibition of adenovirus multiplication by short interfering RNAs directly or indirectly targeting the viral DNA replication machinery. Antiviral Res. 2012, 94:195-207.
17. Liu M., Vakharia V.N. VP1 protein of infectious bursal disease virus modulates the virulence in vivo. Virology 2004, 330:62-73.
18. Liu Y.P., Haasnoot J., ter Brake O., Berkhout B., Konstantinova P. Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res. 2008, 36:2811-2824.
19. Ma Y., Chan C.Y., He M.L. RNA interference and antiviral therapy. World J. Gastroenterol. 2007, 13:5169-5179.
20. Peters M.A., Jackson D.C., Crabb B.S., Browning G.F. Mutation of chicken anemia virus VP2 differentially affects serine/threonine and tyrosine protein phosphatase activities. J. Gen. Virol. 2005, 86:623-630.
21. Shi J., Wang M., Wang J., Wang S., Luo E. Comparison of inhibitory efficacy of short interfering RNAs targeting different genes on Measles virus replication. J. Basic Microbiol. 2012, 52:332-339.
22. Tacken M.G., Peeters B.P., Thomas A.A., Rottier P.J., Boot H.J. Infectious bursal disease virus capsid protein VP3 interacts both with VP1, the RNA-dependent RNA polymerase, and with viral double-stranded RNA. J. Virol. 2002, 76:11301-11311.
23. ter Brake O., Konstantinova P., Ceylan M., Berkhout B. Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol. Ther. 2006, 14:883-892.
24. Travella S., Keller B. Down-regulation of gene expression by RNA-induced gene silencing. Methods Mol. Biol. 2009, 478:185-199.
25. Wang Y., Sun H., Shen P., Zhang X., Xia X. Effective inhibition of infectious bursal disease virus replication by recombinant avian adeno-associated virus-delivered microRNAs. J. Gen. Virol. 2009, 90:1417-1422.
26. Wang Y.S., Ouyang W., Liu X.J., He K.W., Yu S.Q., Zhang H.B., Fan H.J., Lu C.P. Virus-like particles of hepatitis B virus core protein containing five mimotopes of infectious bursal disease virus (IBDV) protect chickens against IBDV. Vaccine 2012, 30:2125-2130.
27. Xiangji L., Feng X., Qingbao C., Weifeng T., Xiaoqing J., Baihe Z., Feng S., Hongyang W., Mengchao W. Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth. J. Viral Hepat. 2011, 18:653-660.
28. Zhou J., Huang F., Hua X., Cui L., Zhang W., Shen Y., Yan Y., Chen P., Ding D., Mou J., Chen Q., Lan D., Yang Z. Inhibition of porcine transmissible gastroenteritis virus (TGEV) replication in mini-pigs by shRNA. Virus Res. 2010, 149:51-55.