Cloning, expression, and functional characterization of secondary amino acid transporters of Lactococcus lactis

Journal of Bacteriology

Volumn 195, Issue 2, 2013, Pages 340-350

  Trip, Hein ^a,b   Mulder, Niels L ^a,c   Lolkema, Juke S ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b TNO   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ACIDIC AMINO ACID; ACIDIC AMINO ACID TRANSPORTER; AGMATINE; ALANINE; AMINO ACID; AMINO ACID TRANSPORTER; ARGININE; AROMATIC AMINO ACID; AROMATIC AMINO ACID TRANSPORTER; ASPARTIC ACID; BRANCHED CHAIN AMINO ACID; CYSTEINE; GLUTAMIC ACID; GLYCINE; HISTIDINE; HISTIDINE TRANSPORTER; LYSINE; LYSINE TRANSPORTER; ORNITHINE; PHENYLALANINE; PUTRESCINE; SERINE; THREONINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; AMINO ACID TRANSPORT; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BINDING AFFINITY; CLONING; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME SPECIFICITY; LACTOBACILLUS DELBRUECKII; LACTOCOCCUS LACTIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; CLONING, MOLECULAR; CULTURE MEDIA; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; LACTOCOCCUS LACTIS; SUBSTRATE SPECIFICITY;

LACTOCOCCUS LACTIS; LACTOCOCCUS LACTIS SUBSP. CREMORIS;

EID: 84872130897     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.01948-12     Document Type: Article

References (51)

1. Delorme C, Godon JJ, Ehrlich SD, Renault P. 1993. Gene inactivation in Lactococcus lactis: histidine biosynthesis. J. Bacteriol. 175:4391-4399.
2. Godon JJ, Delorme C, Bardowski J, Chopin MC, Ehrlich SD, Renault P. 1993. Gene inactivation in Lactococcus lactis: branched-chain amino acid biosynthesis. J. Bacteriol. 175:4383-4390.
3. Kunji ER, Hagting A, De Vries CJ, Juillard V, Haandrikman AJ, Poolman B, Konings WN. 1995. Transport of beta-casein-derived peptides by the oligopeptide transport system is a crucial step in the proteolytic pathway of Lactococcus lactis. J. Biol. Chem. 270:1569-1574.
4. Poolman B, Kunji ER, Hagting A, Juillard V, Konings WN. 1995. The proteolytic pathway of Lactococcus lactis. Soc. Appl. Bacteriol. Symp. Ser. 24:65S-75S.
5. Savijoki K, Ingmer H, Varmanen P. 2006. Proteolytic systems of lactic acid bacteria. Appl. Microbiol. Biotechnol. 71:394-406.
6. Jensen PR, Hammer K. 1993. Minimal requirements for exponential growth of Lactococcus lactis. Appl. Environ. Microbiol. 59:4363-4366.
7. Konings WN. 2002. The cell membrane and the struggle for life of lactic acid bacteria. Antonie Van Leeuwenhoek 82:3-27.
8. Driessen AJ, Molenaar D, Konings WN. 1989. Kinetic mechanism and specificity of the arginine-ornithine antiporter of Lactococcus lactis. J. Biol. Chem. 264:10361-10370.
9. Ladero V, Rattray FP, Mayo B, Martin MC, Fernandez M, Alvarez MA. 2011. Sequencing and transcriptional analysis of the biosynthesis gene cluster of putrescine-producing Lactococcus lactis. Appl. Environ. Microbiol. 77:6409-6418.
10. Molenaar D, Bosscher JS, ten Brink B, Driessen AJ, Konings WN. 1993. Generation of a proton motive force by histidine decarboxylation and electrogenic histidine/histamine antiport in Lactobacillus buchneri. J. Bacteriol. 175:2864-2870.
11. Driessen AJ, de Jong S, Konings WN. 1987. Transport of branched-chain amino acids in membrane vesicles of Streptococcus cremoris. J. Bacteriol. 169:5193-5200.
12. Driessen AJ, Hellingwerf KJ, Konings WN. 1987. Mechanism of energy coupling to entry and exit of neutral and branched chain amino acids in membrane vesicles of Streptococcus cremoris. J. Biol. Chem. 262:12438-12443.
13. Driessen AJ, Kodde J, de Jong S, Konings WN. 1987. Neutral amino acid transport by membrane vesicles of Streptococcus cremoris is subject to regulation by internal pH. J. Bacteriol. 169:2748-2754.
14. Driessen AJ, van Leeuwen C, Konings WN. 1989. Transport of basic amino acids by membrane vesicles of Lactococcus lactis. J. Bacteriol. 171: 1453-1458.
15. Driessen AJ. 1987. Amino acid transport in lactic streptococci. Ph.D. thesis. University of Groningen, Groningen, The Netherlands.
16. Poolman B, Konings WN. 1988. Relation of growth of Streptococcus lactis and Streptococcus cremoris to amino acid transport. J. Bacteriol. 170:700-707
17. Poolman B, Smid EJ, Konings WN. 1987. Kinetic properties of a phosphate- bond-driven glutamate-glutamine transport system in Streptococcus lactis and Streptococcus cremoris. J. Bacteriol. 169:2755-2761.
18. Molenaar D, Hagting A, Alkema H, Driessen AJ, Konings WN. 1993. Characteristics and osmoregulatory roles of uptake systems for proline and glycine betaine in Lactococcus lactis. J. Bacteriol. 175:5438-5444.
19. Den Hengst CD, Groeneveld M, Kuipers OP, Kok J. 2006. Identification and functional characterization of the Lactococcus lactis CodY-regulated branched-chain amino acid permease BcaP (CtrA). J. Bacteriol. 188: 3280-3289.
20. Schuurman-Wolters GK, Poolman B. 2005. Substrate specificity and ionic regulation of GlnPQ from Lactococcus lactis. An ATP-binding cassette transporter with four extracytoplasmic substrate-binding domains. J. Biol. Chem. 280:23785-23790.
21. Saier MH, Jr. 2000. Families of transmembrane transporters selective for amino acids and their derivatives. Microbiology 146:1775-1795.
22. Kuipers OP, de Ruyter PG, Kleerebezem M, de Vos WM. 1998. Quorum sensing-controlled gene expression in lactic acid bacteria. J. Biotechnol. 64:15-21.
23. Pinto JP, Zeyniyev A, Karsens H, Trip H, Lolkema JS, Kuipers OP, Kok J. 2011. pSEUDO, a genetic integration standard for Lactococcus lactis. Appl. Environ. Microbiol. 77:6687-6690.
24. De Ruyter PG, Kuipers OP, de Vos WM. 1996. Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin. Appl. Environ. Microbiol. 62:3662-3667.
25. Solem C, Defoor E, Jensen PR, Martinussen J. 2008. Plasmid pCS1966, a new selection/counterselection tool for lactic acid bacterium strain construction based on the oroP gene, encoding an orotate transporter from Lactococcus lactis. Appl. Environ. Microbiol. 74:4772-4775.
26. Pudlik AM, Lolkema JS. 2012. Rerouting citrate metabolism in Lactococcus lactis to citrate-driven transamination. Appl. Environ. Microbiol. 78: 6665-6673.
27. Jensen NB, Christensen B, Nielsen J, Villadsen J. 2002. The simultaneous biosynthesis and uptake of amino acids by Lactococcus lactis studied by (13)C-labeling experiments. Biotechnol. Bioeng. 78:11-16.
28. Lolkema JS, Slotboom DJ. 1998. Estimation of structural similarity of membrane proteins by hydropathy profile alignment. Mol. Membr. Biol. 15:33-42.
29. +-leucine transporters. Mol. Membr. Biol. 25:567-570.
30. Budin-Verneuil A, Maguin E, Auffray Y, Ehrlich DS, Pichereau V. 2006. Genetic structure and transcriptional analysis of the arginine deiminase (ADI) cluster in Lactococcus lactis MG1363. Can. J. Microbiol. 52:617-622.
31. Sanders JW, Leenhouts K, Burghoorn J, Brands JR, Venema G, Kok J. 1998. A chloride-inducible acid resistance mechanism in Lactococcus lactis and its regulation. Mol. Microbiol. 27:299-310.
32. Stucky K, Hagting A, Klein JR, Matern H, Henrich B, Konings WN, Plapp R. 1995. Cloning and characterization of brnQ, a gene encoding a low-affinity, branched-chain amino acid carrier in Lactobacillus delbruckii subsp. lactis DSM7290. Mol. Gen. Genet. 249:682-690.
33. Romano A, Trip H, Lonvaud-Funel A, Lolkema JS, Lucas PM. 2012. Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteria. Appl. Environ. Microbiol. 78:1953-1961.
34. Nakamura J, Hirano S, Ito H, Wachi M. 2007. Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production. Appl. Environ. Microbiol. 73:4491-4498.
35. Guimont C. 2002. Change of free amino acids in M17 medium after growth of Streptococcus thermophilus and identification of a glutamine transport ATP-binding protein. Int. Dairy J. 12:729-736.
36. Fang G, Konings WN, Poolman B. 2000. Kinetics and substrate speci- ficity of membrane-reconstituted peptide transporter DtpT of Lactococcus lactis. J. Bacteriol. 182:2530-2535.
37. Driessen AJ. 1989. Secondary transport of amino acids by membrane vesicles derived from lactic acid bacteria. Antonie Van Leeuwenhoek 56: 139-160.
38. Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS. 2003. Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch? Nucleic Acids Res. 31:6748-6757.
39. Vitreschak AG, Lyubetskaya EV, Shirshin MA, Gelfand MS, Lyubetsky VA. 2004. Attenuation regulation of amino acid biosynthetic operons in proteobacteria: comparative genomics analysis. FEMS Microbiol. Lett. 234:357-370.
40. Poolman B, Driessen AJ, Konings WN. 1987. Regulation of solute transport in streptococci by external and internal pH values. Microbiol. Rev. 51:498-508.
41. Whipp MJ, Halsall DM, Pittard AJ. 1980. Isolation and characterization of an Escherichia coli K-12 mutant defective in tyrosine- and phenylalanine- specific transport systems. J. Bacteriol. 143:1-7.
42. Hugenholtz J, Dijkstra M, Veldkamp H. 1987. Amino acid limited growth of starter cultures in milk. FEMS Microbiol. Ecol. 45:191-198.
43. Cretenet M, Laroute V, Ulve V, Jeanson S, Nouaille S, Even S, Piot M, Girbal L, Le LY, Loubiere P, Lortal S, Cocaign-Bousquet M. 2011. Dynamic analysis of the Lactococcus lactis transcriptome in cheeses made from milk concentrated by ultrafiltration reveals multiple strategies of adaptation to stresses. Appl. Environ. Microbiol. 77:247-257.
44. Juillard V, Le BD, Kunji ER, Konings WN, Gripon JC, Richard J. 1995. Oligopeptides are the main source of nitrogen for Lactococcus lactis during growth in milk. Appl. Environ. Microbiol. 61:3024-3030.
45. Niven GW, Knight DJ, Mulholland F. 1998. Changes in the concentrations of free amino acids in milk during growth of Lactococcus lactis indicate biphasic nitrogen metabolism. J. Dairy Res. 65:101-107.
46. Anderson JJ, Oxender DL. 1978. Genetic separation of high- and lowaffinity transport systems for branched-chain amino acids in Escherichia coli K-12. J. Bacteriol. 136:168-174.
47. Hashimoto K, Nakamura K, Kuroda T, Yabe I, Nakamatsu T, Kawasaki H. 2010. The protein encoded by NCgl1221 in Corynebacterium glutamicum functions as a mechanosensitive channel. Biosci. Biotechnol. Biochem. 74:2546-2549.
48. Nottebrock D, Meyer U, Krämer R, Morbach S. 2003. Molecular and biochemical characterization of mechanosensitive channels in Corynebacterium glutamicum. FEMS Microbiol. Lett. 218:305-309.
49. Vrljic M, Sahm H, Eggeling L. 1996. A new type of transporter with a new type of cellular function: L-lysine export from Corynebacterium glutamicum. Mol. Microbiol. 22:815-826.
50. Kennerknecht N, Sahm H, Yen MR, Patek M, Saier MH, Jr, Eggeling L. 2002. Export of L-isoleucine from Corynebacterium glutamicum: a twogene- encoded member of a new translocator family. J. Bacteriol. 184: 3947-3956.
51. Trotschel C, Deutenberg D, Bathe B, Burkovski A, Krämer R. 2005. Characterization of methionine export in Corynebacterium glutamicum. J. Bacteriol. 187:3786-3794.