Antiproliferative and apoptotic effects of norethisterone on endometriotic stromal cells in vitro

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 166, Issue 1, 2013, Pages 76-80

  Minami, Toshiyuki ^a   Kosugi, Keiji ^a   Suganuma, Izumi ^b   Yamanaka, Kaoruko ^b   Kusuki, Izumi ^b   Oyama, Tatsuya ^a   Kitawaki, Jo ^b  

^a NIPPON SHINYAKU CO LTD   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Apoptosis; Endometriotic stromal cells; Norethisterone; Progesterone; Proliferation

Indexed keywords

CASPASE 3; CASPASE 7; LACTATE DEHYDROGENASE; NORETHISTERONE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENDOMETRIOTIC STROMAL CELL; ENDOMETRIUM TUMOR; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; PRIORITY JOURNAL; STROMA CELL;

EID: 84872114596     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2012.08.023     Document Type: Article

References (25)

1. L.C. Giudice, and L.C. Kao Endometriosis Lancet 364 2004 1789 1799
2. S.E. Bulun, and Endometriosis New England Journal of Medicine 360 2009 268 279
3. P. Vercellini, E. Somigliana, P. Vigano, A. Abbiati, G. Barbara, and L. Fedele Chronic pelvic pain in women: etiology, pathogenesis and diagnostic approach Gynecological Endocrinology 25 2009 149 158
4. D.L. Olive, and E.A. Pritts Treatment of endometriosis New England Journal of Medicine 345 2001 266 275
5. P. Crosignani, D. Olive, A. Bergqvist, and A. Luciano Advances in the management of endometriosis: an update for clinicians Human Reproduction Update 12 2006 179 189
6. J. Kitawaki, H. Ishihara, M. Kiyomizu, and H. Honjo Maintenance therapy involving a tapering dose of danazol or mid/low doses of oral contraceptive after gonadotropin-releasing hormone agonist treatment for endometriosis- associated pelvic pain Fertility and Sterility 89 2008 1831 1835
7. J. Kitawaki, I. Kusuki, K. Yamanaka, and I. Suganuma Maintenance therapy with dienogest following gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain European Journal of Obstetrics, Gynecology, and Reproductive Biology 157 2011 212 216
8. H.J. Park, Y.A. Koo, B.K. Yoon, and D. Choi Postoperative long-term maintenance therapy with oral contraceptives after gonadotropin-releasing hormone analog treatment in women with ovarian endometrioma Journal of Minimally Invasive Gynecology 16 2009 34 39
9. D. Levy, S. Christin-Maitre, and I. Leroy The endometrial approach in contraception Annals of the New York Academy of Sciences 828 1997 59 83
10. G.F. Meresman, L. Auge, R.I. Baranao, E. Lombardi, M. Tesone, and C. Sueldo Oral contraceptives suppress cell proliferation and enhance apoptosis of eutopic endometrial tissue from patients with endometriosis Fertility and Sterility 77 2002 1141 1147
11. H.F. Taitel, and M.E. Kafrissen Norethindrone-a review of therapeutic applications International Journal of Fertility and Menopausal Studies 40 1995 207 223
12. C.L. Casey, and C.A. Murray HT update: spotlight on estradiol/ norethindrone acetate combination therapy Clinical and Interventional Aging 3 2008 9 16
13. T. Harada, M. Momoeda, Y. Taketani, H. Hoshiai, and N. Terakawa Low-dose oral contraceptive pill for dysmenorrhea associated with endometriosis: a placebo-controlled, double-blind, randomized trial Fertility and Sterility 90 2008 1583 1588
14. B. Dursun, Z. He, H. Somerset, D.J. Oh, S. Faubel, and C.L. Edelstein Caspases and calpain are independent mediators of cisplatin-induced endothelial cell necrosis American Journal of Physiology. Renal Physiology 291 2006 F578 F587
15. E.S. Surrey, and J. Halme Direct effects of medroxyprogesterone acetate, danazol, and leuprolide acetate on endometrial stromal cell proliferation in vitro Fertility and Sterility 58 1992 273 278
16. H. Okada, T. Nakajima, T. Yoshimura, K. Yasuda, and H. Kanzaki The inhibitory effect of dienogest, a synthetic steroid, on the growth of human endometrial stromal cells in vitro Molecular Human Reproduction 7 2001 341 347
17. L. Fu, Y. Osuga, and C. Morimoto Dienogest inhibits BrdU uptake with G0/G1 arrest in cultured endometriotic stromal cells Fertility and Sterility 89 2008 1344 1347
18. T. Harada, M. Momoeda, and Y. Taketani Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis-a randomized, double-blind, multicenter, controlled trial Fertility and Sterility 91 2009 675 681
19. S. Saperstein, R.A. Edgren, and G.J. Lee Bioequivalence of two oral contraceptive drugs containing norethindrone and ethinyl estradiol Contraception 40 1989 581 590
20. L. Tseng, and H.H. Zhu Regulation of progesterone receptor messenger ribonucleic acid by progestin in human endometrial stromal cells Biology of Reproduction 57 1997 1360 1366
21. J. Prange-Kiel, G.M. Rune, M. Zwirner, D. Wallwiener, and L. Kiesel Regulation of estrogen receptor α and progesterone receptor (isoform A and B) expression in cultured human endometrial cells Experimental and Clinical Endocrinology and Diabetes 109 2001 231 237
22. A. Agic, S. Djalali, K. Diedrich, and D. Hornung Apoptosis in endometriosis Gynecologic and Obstetric Investigation 68 2009 217 223
23. M. Nishida, K. Nasu, T. Ueda, J. Fukuda, N. Takai, and I. Miyakawa Endometriotic cells are resistant to interferon-γ-induced cell growth inhibition and apoptosis: a possible mechanism involved in the pathogenesis of endometriosis Molecular Human Reproduction 11 2005 29 34
24. M. Izawa, T. Harada, I. Deura, F. Taniguchi, T. Iwabe, and N. Terakawa Drug-induced apoptosis was markedly attenuated in endometriotic stromal cells Human Reproduction 21 2006 600 604
25. D. Africander, N. Verhoog, and J.P. Hapgood Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception Steroids 76 2011 636 652