Primate cathelicidin orthologues display different structures and membrane interactions

Biochemical Journal

Volumn 417, Issue 3, 2009, Pages 727-735

  Morgera, Francesca ^a,b   Vaccari, Lisa ^b   Antcheva, Nikolinka ^a   Scaini, Denis ^b   Pacor, Sabrina ^a   Tossi, Alessandro ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b SINCROTRONE TRIESTE   (Italy)

Author keywords

Antimicrobial peptide; Attenuated total reflection (ATR) spectroscopy; Membrane interaction; Peptide structuring; Primate cathelicidin

Indexed keywords

AFM; ANTI-BACTERIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; ATR FTIR; ATTENUATED TOTAL REFLECTION (ATR) SPECTROSCOPY; ATTENUATED TOTAL REFLECTIONS; BACTERIAL CELLS; BI-LAYER; BIOLOGICAL ACTIVITIES; BULK SOLUTIONS; CATHELICIDIN; CELL ACTIVITY; DIFFERENT STRUCTURE; FREEFORMS; FTIR; HELICAL CONFORMATION; MODEL MEMBRANES; MODULATING FUNCTIONS; ORTHOLOGUES; PERMEABILIZATION; POSITIVE SELECTION; PRIMATE CATHELICIDIN; STRUCTURAL CHARACTERISTICS; STRUCTURAL VARIATIONS; WALL LAYERS;

AMINES; BIOLOGICAL MEMBRANES; CYTOLOGY; DRUG INTERACTIONS; DYES; ELECTROMAGNETIC WAVE REFLECTION; FETAL MONITORING; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GENE ENCODING; LIPID BILAYERS; MAMMALS; MEMBRANES; POLYPEPTIDES;

CELL MEMBRANES;

CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CATHELICIDIN RL 37; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE BINDING PROTEIN; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN;

ANALYTIC METHOD; ANTIBACTERIAL ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; ATTENUATED TOTAL REFLECTION; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BIOLOGICAL ACTIVITY; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; GROWTH INHIBITION; HOST CELL; HUMAN; IMMUNOMODULATION; INFRARED SPECTROSCOPY; LIPID BILAYER; MEMBRANE BINDING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ORANG UTAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; RHESUS MONKEY; SPECIES COMPARISON; ANIMAL; CELL MEMBRANE; CHEMISTRY; GENETICS; METABOLISM; PHYSIOLOGY; PRIMATE; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); PONGO PYGMAEUS; PRIMATES;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; HUMANS; LIPID BILAYERS; PRIMATES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 59849118467     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081726     Document Type: Article

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