Distinct roles of ser-764 and lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 393-400

  Castro Núñez, Lydia ^a   Bloem, Esther ^a   Boon Spijker, Mariëtte G ^a   Van Der Zwaan, Carmen ^a   Van Den Biggelaar, Maartje ^a   Mertens, Koen ^b   Meijer, Alexander B ^a,b  

^a SANQUIN RESEARCH   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; AMINO GROUP; BINDING MECHANISMS; CHEMICALLY MODIFIED; COAGULATION FACTOR; COMPLEX ASSEMBLY; COMPLEX FORMATIONS; FOOTPRINTING; IN-VIVO; LIGHT CHAIN; LYSINE RESIDUES; N-TERMINALS; NANO-LC-MS; SURFACE PLASMONS; VON WILLEBRAND FACTOR;

BINDING SITES; CHEMICAL MODIFICATION; COAGULATION; GLYCOPROTEINS; PEPTIDES;

AMINO ACIDS;

BLOOD CLOTTING FACTOR 8; LYSINE; SERINE; THROMBIN; VON WILLEBRAND FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL MODIFICATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR VIII; HUMANS; KINETICS; LYSINE; MASS SPECTROMETRY; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SURFACE PLASMON RESONANCE; VON WILLEBRAND FACTOR;

EID: 84872088575     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.400572     Document Type: Article

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