-
1
-
-
0031781603
-
Inflammatory bowel disease: Etiology and pathogenesis
-
Fiochi C: Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998;115:182-205.
-
(1998)
Gastroenterology
, vol.115
, pp. 182-205
-
-
Fiochi, C.1
-
2
-
-
0037043658
-
Inflammatory bowel disease
-
DOI 10.1056/NEJMra020831
-
Podolsky D: Inflammatory bowel disease. N Engl J Med 2002;347:417-429. (Pubitemid 34851835)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.6
, pp. 417-429
-
-
Podolsky, D.K.1
-
3
-
-
0035082973
-
Different subsets of enteric bacteria induce and perpetuate experimental colitis in rats and mice
-
DOI 10.1128/IAI.69.4.2277-2285.2001
-
Rath HC, Schultz M, Freitag R, Dieleman LA, Li F, Linde HJ, Schölmerich J, Sartor RB: Different subsets of enteric bacteria induce and perpetuate experimental colitis in rats and mice. Infect Immun 2001;69:2277-2285. (Pubitemid 32241818)
-
(2001)
Infection and Immunity
, vol.69
, Issue.4
, pp. 2277-2285
-
-
Rath, H.C.1
Schultz, M.2
Freitag, R.3
Dieleman, L.A.4
Li, F.5
Linde, H.-J.6
Scholmerich, J.7
Sartor, R.B.8
-
4
-
-
15544369658
-
Host-bacterial mutualism in the human intestine
-
DOI 10.1126/science.1104816
-
Backhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI: Host-bacterial mutualism in the human intestine. Science 2005;307:1915-1920. (Pubitemid 40404694)
-
(2005)
Science
, vol.307
, Issue.5717
, pp. 1915-1920
-
-
Backhed, F.1
Ley, R.E.2
Sonnenburg, J.L.3
Peterson, D.A.4
Gordon, J.I.5
-
5
-
-
68949210469
-
Influence of standard treatment on ileal and colonic antimicrobial defensin expression in active Crohn's disease
-
Kubler I, Koslowski MJ, Gersemann M, Fellermann K, Beisner J, Becker S, Rothfuss K, Herrlinger KR, Stange EF, Wehkamp J: Influence of standard treatment on ileal and colonic antimicrobial defensin expression in active Crohn's disease. Aliment Pharmacol Ther 2009;30:621-633.
-
(2009)
Aliment Pharmacol Ther
, vol.30
, pp. 621-633
-
-
Kubler, I.1
Koslowski, M.J.2
Gersemann, M.3
Fellermann, K.4
Beisner, J.5
Becker, S.6
Rothfuss, K.7
Herrlinger, K.R.8
Stange, E.F.9
Wehkamp, J.10
-
6
-
-
75149154705
-
FOXO-dependent regulation of innate immune homeostasis
-
Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, Carrera P, Inhester T, Schultze J, Hoch M: FOXO-dependent regulation of innate immune homeostasis. Nature 2010;463:369-373.
-
(2010)
Nature
, vol.463
, pp. 369-373
-
-
Becker, T.1
Loch, G.2
Beyer, M.3
Zinke, I.4
Aschenbrenner, A.C.5
Carrera, P.6
Inhester, T.7
Schultze, J.8
Hoch, M.9
-
8
-
-
0033870325
-
Mucins and inflammatory bowel disease
-
DOI 10.1136/pmj.76.898.473
-
Shirazi T, Longman RJ, Corfield AP, Probert CSJ: Mucins and inflammatory bowel disease. Postgrad Med J 2000;76:473-478. (Pubitemid 30639056)
-
(2000)
Postgraduate Medical Journal
, vol.76
, Issue.898
, pp. 473-478
-
-
Shirazi, T.1
Longman, R.J.2
Corfield, A.P.3
Probert, C.S.J.4
-
9
-
-
0027076579
-
Mucus: The front line of intestinal mucosal defense
-
DOI 10.1111/j.1749-6632.1992.tb39760.x
-
Lamont JT: Mucus: the front line of intestinal mucosal defense. Ann N Y Acad Sci 1992;664:190-201. (Pubitemid 23022849)
-
(1992)
Annals of the New York Academy of Sciences
, vol.664
, pp. 190-201
-
-
Lamont, J.T.1
-
10
-
-
54449083567
-
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
-
Johannson MEV, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC: The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci USA 2008;105:15064-15069.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15064-15069
-
-
Johannson, M.E.V.1
Phillipson, M.2
Petersson, J.3
Velcich, A.4
Holm, L.5
Hansson, G.C.6
-
11
-
-
0030737814
-
Histochemistry of the surface mucous gel layer of the human colon
-
Matsuo K, Ota H, Akamatsu T, Sugiyama A, Katsuyama T: Histochemistry of the surface mucous gel layer of the human colon. Gut 1997;40:782-790.
-
(1997)
Gut
, vol.40
, pp. 782-790
-
-
Matsuo, K.1
Ota, H.2
Akamatsu, T.3
Sugiyama, A.4
Katsuyama, T.5
-
12
-
-
0024420446
-
Intestinal surfactant-like material. A novel secretory product of the rat enterocyte
-
DeSchryver-Kecskemeti K, Eliakim R, Carroll S, Stenson WF, Moxley MA, Alpers DH: Intestinal surfactant-like material. A novel secretory product of the rat enterocyte. J Clin Invest 1989;84:1355-1361. (Pubitemid 19247612)
-
(1989)
Journal of Clinical Investigation
, vol.84
, Issue.4
, pp. 1355-1361
-
-
DeSchryver-Kecskemeti, K.1
Eliakim, R.2
Carroll, S.3
Stenson, W.F.4
Moxley, M.A.5
Alpers, D.H.6
-
14
-
-
33748447921
-
Unique molecular signatures of glycerophospholipid species in different rat tissues analyzed by tandem mass spectrometry
-
DOI 10.1016/j.bbalip.2006.05.010, PII S1388198106001570
-
Hicks AM, DeLong CJ, Thomas MJ, Samuel M, Cui Z: Unique molecular signatures of glycerophospholipid species in different rat tissues analyzed by tandem mass spectrometry. Biochim Biophys Acta 2006;1761:1022-1029. (Pubitemid 44354286)
-
(2006)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1761
, Issue.9
, pp. 1022-1029
-
-
Hicks, A.M.1
DeLong, C.J.2
Thomas, M.J.3
Samuel, M.4
Cui, Z.5
-
15
-
-
0036380937
-
Surface-active phospholipid: A Pandora's box of clinical applications. Part II. Barrier and lubricating properties
-
Hills BA: Surface-active phospholipid: a Pandora's box of clinical applications. Part II. Barrier and lubricating properties. Intern Med J 2002;32:242-251.
-
(2002)
Intern Med J
, vol.32
, pp. 242-251
-
-
Hills, B.A.1
-
16
-
-
0028915433
-
The hydrophobic barrier properties of gastrointestinal mucus
-
Review
-
Lichtenberger LM: The hydrophobic barrier properties of gastrointestinal mucus. Annu Rev Physiol 1995;57:565-583. Review.
-
(1995)
Annu Rev Physiol
, vol.57
, pp. 565-583
-
-
Lichtenberger, L.M.1
-
17
-
-
33847416255
-
Phospholipids as implant coatings
-
DOI 10.1007/s10856-006-0702-9, Special Issue: Selected Papers from the 20th European Conference on Biomaterials, Nantes, France
-
Willumeit R, Schuster A, Iliev P, Linser S, Feyerabend F: Phospholipids as implant coatings. J Mater Sci Mater Med 2007;18:367-380. (Pubitemid 46332861)
-
(2007)
Journal of Materials Science: Materials in Medicine
, vol.18
, Issue.2
, pp. 367-380
-
-
Willumeit, R.1
Schuster, A.2
Iliev, P.3
Linser, S.4
Feyerabend, F.5
-
18
-
-
0027377354
-
Phospholipid impregnation of abdominal rubber drains: Resistance to bacterial adherence but no effect on drain-induced bacterial translocation
-
Guo W, Andersson R, Odselius R, Ljungh A, Wadström T, Bengmark S: Phospholipid impregnation of abdominal rubber drains: resistance to bacterial adherence but no effect on drain-induced bacterial translocation. Res Exp Med 1993;193:285-296. (Pubitemid 23319583)
-
(1993)
Research in Experimental Medicine
, vol.193
, Issue.5
, pp. 285-296
-
-
Guo, W.1
Andersson, R.2
Odselius, R.3
Ljungh, A.4
Wadstrom, T.5
Bengmark, S.6
-
19
-
-
2442703827
-
Evidence of luminal phosphatidylcholine secretion in rat ileum
-
DOI 10.1016/j.bbalip.2004.01.009, PII S1388198104000265
-
Ehehalt R, Jochims C, Lehmann WD, Erben G, Staffer S, Reininger C, Stremmel W: Evidence of luminal phosphatidylcholine secretion in rat ileum. Biochim Biophys Acta 2004;1682:63-71. (Pubitemid 38670536)
-
(2004)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1682
, Issue.1-3
, pp. 63-71
-
-
Ehehalt, R.1
Jochims, C.2
Lehmann, W.-D.3
Erben, G.4
Staffer, S.5
Reininger, C.6
Stremmel, W.7
-
20
-
-
0028887607
-
Synthesis and parallel secretion of rat intestinal alkaline phosphatase and a surfactant-like particle protein
-
Alpers DH, Zhang Y, Ahnen DJ: Synthesis and parallel secretion of rat intestinal alkaline phosphatase and a surfactant-like particle protein. Am J Physiol 1995;268:E1205-E1214.
-
(1995)
Am J Physiol
, vol.268
-
-
Alpers, D.H.1
Zhang, Y.2
Ahnen, D.J.3
-
21
-
-
0028896376
-
Appearance of surfactant-like particles in apical medium of Caco-2 cells may occur via tight junctions
-
Engle MJ, Grove ML, Becich MJ, Mahmood A, Alpers DH: Appearance of surfactant-like particles in apical medium of Caco-2 cells may occur via tight junctions. Am J Physiol 1995;268:C1401-C1413.
-
(1995)
Am J Physiol
, vol.268
-
-
Engle, M.J.1
Grove, M.L.2
Becich, M.J.3
Mahmood, A.4
Alpers, D.H.5
-
22
-
-
4143054569
-
Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis patients. A quantitative approach by nanoelectrospray-tandem mass spectrometry
-
DOI 10.1080/00365520410006233
-
Ehehalt R, Wagenblast J, Erben G, Lehmann WD, Hinz U, Merle U, Stremmel W: Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis patients. A quantitative approach by nano-Electrospray-tandem mass spectrometry. Scand J Gastroenterol 2004;39:737-742. (Pubitemid 39093247)
-
(2004)
Scandinavian Journal of Gastroenterology
, vol.39
, Issue.8
, pp. 737-742
-
-
Ehehalt, R.1
Wagenblast, J.2
Erben, G.3
Lehmann, W.-D.4
Hinz, U.5
Merle, U.6
Stremmel, W.7
-
23
-
-
70350329474
-
Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: A clue to pathogenesis
-
Braun A, Treede I, Gotthardt D, Tietje A, Zahn A, Ruhwald R, Schoenfeld U, Welsch T, Kienle P, Erben G, Lehmann WD, Fuellekrug J, Stremmel W, Ehehalt R: Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: a clue to pathogenesis. Inflamm Bowel Dis 2009;15:1705-1720.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1705-1720
-
-
Braun, A.1
Treede, I.2
Gotthardt, D.3
Tietje, A.4
Zahn, A.5
Ruhwald, R.6
Schoenfeld, U.7
Welsch, T.8
Kienle, P.9
Erben, G.10
Lehmann, W.D.11
Fuellekrug, J.12
Stremmel, W.13
Ehehalt, R.14
-
24
-
-
80051588898
-
Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect
-
Braun A, Schoenfeld U, Welsch T, Kadmon M, Funke B, Gotthardt D, Zahn A, Autschbach F, Kienle P, Zharnikov M, Grunze M, Stremmel W, Ehehalt R: Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect. Int J Colorectal Dis 2011;26:898-998.
-
(2011)
Int J Colorectal Dis
, vol.26
, pp. 898-998
-
-
Braun, A.1
Schoenfeld, U.2
Welsch, T.3
Kadmon, M.4
Funke, B.5
Gotthardt, D.6
Zahn, A.7
Autschbach, F.8
Kienle, P.9
Zharnikov, M.10
Grunze, M.11
Stremmel, W.12
Ehehalt, R.13
-
25
-
-
70349312643
-
The kindling protein family: New members to the club of focal adhesion proteins
-
Meves A, Stremmel C, Gottschalk K, Fässler R: The kindling protein family: new members to the club of focal adhesion proteins. Trends Cell Biol 2009;19:504-512.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 504-512
-
-
Meves, A.1
Stremmel, C.2
Gottschalk, K.3
Fässler, R.4
-
26
-
-
58149154658
-
Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction
-
Ussar S, Moser M, Widmaier M, Rognoni E, Harrer C, Genzel-Boroviczeny O, Fässler R: Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction. PLoS Genet 2008;4:e1000289.
-
(2008)
PLoS Genet
, vol.4
-
-
Ussar, S.1
Moser, M.2
Widmaier, M.3
Rognoni, E.4
Harrer, C.5
Genzel-Boroviczeny, O.6
Fässler, R.7
-
27
-
-
43449096855
-
Retarded release phosphatidylcholine: A new therapeutic option for ulcerative colitis
-
A. Dignass, D. Rachmilewitz, E. F. Stange, J. V. Weinstock eds:, Heidelberg, Springer
-
Karner M, Ehehalt R, Stremmel W: Retarded release phosphatidylcholine: A new therapeutic option for ulcerative colitis; in A. Dignass, D. Rachmilewitz, E. F. Stange, J. V. Weinstock (eds): Immunoregulation in Inflammatory Bowel Diseases - Current Understanding and Innovation. Heidelberg, Springer, 2007, pp 161-170.
-
(2007)
Immunoregulation in Inflammatory Bowel Diseases - Current Understanding and Innovation
, pp. 161-170
-
-
Karner, M.1
Ehehalt, R.2
Stremmel, W.3
-
28
-
-
21044446805
-
Reinforcing the mucus: A new therapeutic approach for ulcerative colitis?
-
DOI 10.1136/gut.2004.058453
-
Gibson PR, Muir JG: Reinforcing the mucus: a new therapeutic approach for ulcerative colitis? Gut 2005;54:900-903. (Pubitemid 40873897)
-
(2005)
Gut
, vol.54
, Issue.7
, pp. 900-903
-
-
Gibson, P.R.1
Muir, J.G.2
-
29
-
-
38449107095
-
Phosphatidylcholine in steroid refractory chronic ulcerative colitis - Is it all in the mucus?
-
Nazareth M, Mahadevan U: Phosphatidylcholine in steroid refractory chronic ulcerative colitis - is it all in the mucus? Ann Intern Med 2007;147:603-610.
-
(2007)
Ann Intern Med
, vol.147
, pp. 603-610
-
-
Nazareth, M.1
Mahadevan, U.2
-
30
-
-
0042471938
-
Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria
-
DOI 10.1038/ncb1036
-
Anes E, Kühnel MP, Bos E, Moniz-Pereira J, Habermann A, Griffiths G: Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria. Nat Cell Biol 2003;5:793-802. (Pubitemid 37087167)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.9
, pp. 793-802
-
-
Anes, E.1
Kuhnel, M.P.2
Bos, E.3
Moniz-Pereira, J.4
Habermann, A.5
Griffiths, G.6
-
31
-
-
68249135240
-
TNF-alpha-induced up-regulation of proinflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells
-
Treede I, Braun A, Jeliaskova P, Giese T, Füllekrug J, Griffiths G, Stremmel W, Ehehalt R: TNF-alpha-induced up-regulation of proinflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells. BMC Gastroenterol 2009;9:53.
-
(2009)
BMC Gastroenterol
, vol.9
, pp. 53
-
-
Treede, I.1
Braun, A.2
Jeliaskova, P.3
Giese, T.4
Füllekrug, J.5
Griffiths, G.6
Stremmel, W.7
Ehehalt, R.8
-
32
-
-
59849086846
-
Role of lipids in killing mycobacteria by macrophages: Evidence for NFkappaB-dependent and -independent killing induced by different lipids
-
Gutierrez MG, Gonzalez AP, Anes E, Griffiths G: Role of lipids in killing mycobacteria by macrophages: evidence for NFkappaB-dependent and -independent killing induced by different lipids. Cell Microbiol 2009;11:406-420.
-
(2009)
Cell Microbiol
, vol.11
, pp. 406-420
-
-
Gutierrez, M.G.1
Gonzalez, A.P.2
Anes, E.3
Griffiths, G.4
-
33
-
-
0034193240
-
The p65/RelA subunit of NF-κB interacts with actin-containing structures
-
DOI 10.1006/excr.2000.4830
-
Are AF, Galkin VE, Pospelova TV, Pinaev GP: The p65/RelA subunit of NF-kappaB interacts with actin-containing structures. Exp Cell Res 2000;256:533-544. (Pubitemid 30244211)
-
(2000)
Experimental Cell Research
, vol.256
, Issue.2
, pp. 533-544
-
-
Are, A.F.1
Galkin, V.E.2
Pospelova, T.V.3
Pinaev, G.P.4
-
34
-
-
21044457089
-
Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis
-
DOI 10.1136/gut.2004.052316
-
Stremmel W, Merle U, Zahn A, Autschbach F, Hinz U, Ehehalt R: Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Gut 2005;54:966-971. (Pubitemid 40873911)
-
(2005)
Gut
, vol.54
, Issue.7
, pp. 966-971
-
-
Stremmel, W.1
Merle, U.2
Zahn, A.3
Autschbach, F.4
Hinz, U.5
Ehehalt, R.6
-
35
-
-
77951730355
-
Delayed release phosphatidylcholine in chronic-active ulcerative colitis: A randomized, doubleblinded, dose finding study
-
Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M: Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, doubleblinded, dose finding study. J Clin Gastroenterol 2010;44:e101-e107.
-
(2010)
J Clin Gastroenterol
, vol.44
-
-
Stremmel, W.1
Braun, A.2
Hanemann, A.3
Ehehalt, R.4
Autschbach, F.5
Karner, M.6
-
36
-
-
38449107095
-
Efficacy of retarded release phosphatidylcholine for treatment of chronic, steroid refractory ulcerative colitis
-
Stremmel W, Ehehalt R, Autschbach F, Karner M: Efficacy of retarded release phosphatidylcholine for treatment of chronic, steroid refractory ulcerative colitis. Ann Intern Med 2007;147:603-610.
-
(2007)
Ann Intern Med
, vol.147
, pp. 603-610
-
-
Stremmel, W.1
Ehehalt, R.2
Autschbach, F.3
Karner, M.4
-
37
-
-
77952886843
-
PPARgamma agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells
-
Ogasawara N, Kojima T, Go M, Ohkuni T, Koizumi JI, Kamekura R, Masaki T, Murata M, Tanaka S, Fuchimoto J, Himi T, Sawada N: PPARgamma agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells. Pharmacol Res 2010;61:489-498.
-
(2010)
Pharmacol Res
, vol.61
, pp. 489-498
-
-
Ogasawara, N.1
Kojima, T.2
Go, M.3
Ohkuni, T.4
Koizumi, J.I.5
Kamekura, R.6
Masaki, T.7
Murata, M.8
Tanaka, S.9
Fuchimoto, J.10
Himi, T.11
Sawada, N.12
-
38
-
-
79952037111
-
Structured illumination microscopy of autofluorescent aggregations in human tissue
-
Best G, Amberger R, Baddeley D, Ach T, Dithmar S, Heintzmann R, Cremer C: Structured illumination microscopy of autofluorescent aggregations in human tissue. Micron 2011;42:330-335.
-
(2011)
Micron
, vol.42
, pp. 330-335
-
-
Best, G.1
Amberger, R.2
Baddeley, D.3
Ach, T.4
Dithmar, S.5
Heintzmann, R.6
Cremer, C.7
-
39
-
-
0029186255
-
Confocal analysis of hepatocellular longchain fatty acid uptake
-
Elsing C, Winn-Börner U, Stremmel W: Confocal analysis of hepatocellular longchain fatty acid uptake. Am J Physiol 1995;269:G842-G851.
-
(1995)
Am J Physiol
, vol.269
-
-
Elsing, C.1
Winn-Börner, U.2
Stremmel, W.3
-
40
-
-
33846004766
-
Proteomics fingerprinting of phagosome maturation and evidence for the role of a Gα during uptake
-
DOI 10.1074/mcp.M600113-MCP200
-
Gotthardt D, Blancheteau V, Bosserhoff A, Ruppert T, Delorenzi M, Soldati T: Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake. Mol Cell Proteomics 2006;5:2228-2243. (Pubitemid 46040630)
-
(2006)
Molecular and Cellular Proteomics
, vol.5
, Issue.12
, pp. 2228-2243
-
-
Gotthardt, D.1
Blancheteau, V.2
Bosserhoff, A.3
Ruppert, T.4
Delorenzi, M.5
Soldati, T.6
-
41
-
-
84855690770
-
S100A9 is a biliary protein marker of disease activity in primary sclerosing cholangitis
-
Reinhard L, Rupp C, Riedel HD, Ruppert T, Giese T, Flechtenmacher C, Weiss KH, Kloeters-Plachky P, Stremmel W, Schirmacher P, Sauer P, Gotthardt DN: S100A9 is a biliary protein marker of disease activity in primary sclerosing cholangitis. PLoS One 2012;7:e29821.
-
(2012)
PLoS One
, vol.7
-
-
Reinhard, L.1
Rupp, C.2
Riedel, H.D.3
Ruppert, T.4
Giese, T.5
Flechtenmacher, C.6
Weiss, K.H.7
Kloeters-Plachky, P.8
Stremmel, W.9
Schirmacher, P.10
Sauer, P.11
Gotthardt, D.N.12
|