VEGF levels and the angiogenic potential of the microenvironment can affect surgical strategy for colorectal liver metastasis

Cell Adhesion and Migration

Volumn 6, Issue 6, 2012, Pages 569-573

  Eveno, Clarisse ^a   Pocard, Marc ^a  

^a Hôpital Lariboisière   (France)

Author keywords

Angiogenesis; Colorectal liver metastases; Microenvironment; Pre metastatic niche; Surgical resection; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; VASCULOTROPIN;

ANGIOGENESIS; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; COLORECTAL CANCER; COLORECTAL LIVER METASTASIS; GENE EXPRESSION; HUMAN; LAPAROTOMY; LIVER METASTASIS; REVIEW; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84872078311     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.23247     Document Type: Review

References (29)

1. http://publications.cancerresearchuk.org/
2. Rougier P, Milan C, Lazorthes F, Fourtanier G, Partensky C, Baumel H, et al. Prospective study of prognostic factors in patients with unresected hepatic metastases from colorectal cancer. Fondation Française de Cancérologie Digestive. Br J Surg 1995; 82:1397- 400; PMID:7489177; http://dx.doi.org/10.1002/ bjs.1800821034.
3. Lim C, Farges O. Portal vein occlusion before major hepatectomy in patients with colorectal liver metastases: rationale, indications, technical aspects, complications and outcome. J Visc Surg 2012; 149:e86-96; PMID:22504072; http://dx.doi.org/10.1016/j.jviscsurg. 2012.03.003.
4. Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P, et al.; EORTC Gastro- Intestinal Tract Cancer Group; Cancer Research UK; Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALMCAO); Australasian Gastro-Intestinal Trials Group (AGITG); Fédération Francophone de Cancérologie Digestive (FFCD). Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 2008; 371:1007-16; PMID:18358928; http:// dx.doi.org/10.1016/S0140-6736(08)60455-9.
5. Nathan H, Bridges JF, Cosgrove DP, Diaz LA Jr., Laheru DA, Herman JM, et al. Treating patients with colon cancer liver metastasis: a nationwide analysis of therapeutic decision making. Ann Surg Oncol 2012; 19:3668-76; PMID:22875647; http://dx.doi. org/10.1245/s10434-012-2564-3.
6. Power DG, Kemeny NE. Role of adjuvant therapy after resection of colorectal cancer liver metastases. J Clin Oncol 2010; 28:2300-9; PMID:20368552; http:// dx.doi.org/10.1200/JCO.2009.26.9340.
7. Nordlinger B, Guiguet M, Vaillant JC, Balladur P, Boudjema K, Bachellier P, et al.; Association Française de Chirurgie. Surgical resection of colorectal carcinoma metastases to the liver. A prognostic scoring system to improve case selection, based on 1568 patients. Cancer 1996; 77:1254-62; PMID:8608500; http://dx.doi.org/10.1002/ (SICI)1097-0142(19960401)77:7<1254:: AIDCNCR5> 3.0.CO;2-I.
8. Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 1999; 230:309-18, discussion 318-21; PMID:10493478; http://dx.doi. org/10.1097/00000658-199909000-00004. 10. 11. 12. 13. 14. 15. 16. 17.
9. Larsen AK, Ouaret D, El Ouadrani K, Petitprez A. Targeting EGFR and VEGF(R) pathway cross-talk in tumor survival and angiogenesis. Pharmacol Ther 2011; 131:80-90; PMID:21439312; http://dx.doi. org/10.1016/j.pharmthera.2011.03. 012.
10. Karoui M, Roudot-Thoraval F, Mesli F, Mitry E, Aparicio T, Des Guetz G, et al. Primary colectomy in patients with stage IV colon cancer and unresectable distant metastases improves overall survival: results of a multicentric study. Dis Colon Rectum 2011; 54:930- 8; PMID:21730780; http://dx.doi.org/10.1097/ DCR.0b013e31821cced0.
11. Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005; 438:820-7; PMID:16341007; http://dx.doi.org/10.1038/ nature04186.
12. van der Wal GE, Gouw AS, Kamps JA, Moorlag HE, Bulthuis ML, Molema G, et al. Angiogenesis in synchronous and metachronous colorectal liver metastases: the liver as a permissive soil. Ann Surg 2012; 255:86- 94; PMID:22156924; http://dx.doi.org/10.1097/ SLA.0b013e318238346a.
13. Stillwell AP, Buettner PG, Ho YH. Meta-analysis of survival of patients with stage IV colorectal cancer managed with surgical resection versus chemotherapy alone. World J Surg 2010; 34:797-807; PMID:20054541; http://dx.doi.org/10.1007/s00268-009-0366-y.
14. Stone RL, Nick AM, McNeish IA, Balkwill F, Han HD, Bottsford-Miller J, et al. Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med 2012; 366:610- 8; PMID:22335738; http://dx.doi.org/10.1056/ NEJMoa1110352.
15. Gao D, Nolan DJ, Mellick AS, Bambino K, McDonnell K, Mittal V. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science 2008; 319:195-8; PMID:18187653; http://dx.doi. org/10.1126/science.1150224.
16. Lyden D, Young AZ, Zagzag D, Yan W, Gerald W, O'Reilly R, et al. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature 1999; 401:670-7; PMID:10537105; http://dx.doi.org/10.1038/ 44334.
17. Ruzinova MB, Schoer RA, Gerald W, Egan JE, Pandolfi PP, Rafii S, et al. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell 2003; 4:277-89; PMID:14585355; http:// dx.doi.org/10.1016/S1535-6108(03)00240-X.
18. Langenberg MH, Nijkamp MW, Roodhart JM, Snoeren N, Tang T, Shaked Y, et al. Liver surgery induces an immediate mobilization of progenitor cells in liver cancer patients: A potential role for G-CSF. Cancer Biol Ther 2010; 9:743-8; PMID:20215863; http://dx.doi.org/10.4161/cbt.9.9.11551.
19. Li CX, Shao Y, Ng KT, Liu XB, Ling CC, Ma YY, et al. FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells. PLoS One 2012; 7:e32380; PMID:22384233; http://dx.doi.org/10. 1371/journal.pone.0032380.
20. Aussilhou B, Dokmak S, Faivre S, Paradis V, Vilgrain V, Belghiti J. Preoperative liver hypertrophy induced by portal flow occlusion before major hepatic resection for colorectal metastases can be impaired by bevacizumab. Ann Surg Oncol 2009; 16:1553-9; PMID:19363584; http://dx.doi.org/10.1245/s10434-009- 0447-z.
21. Zorzi D, Chun YS, Madoff DC, Abdalla EK, Vauthey JN. Chemotherapy with bevacizumab does not affect liver regeneration after portal vein embolization in the treatment of colorectal liver metastases. Ann Surg Oncol 2008; 15:2765-72; PMID:18636296; http:// dx.doi.org/10.1245/s10434-008-0035-7.
22. Yoon SS, Kim SH, Gonen M, Heffernan NM, Detwiller KY, Jarnagin WR, et al. Profile of plasma angiogenic factors before and after hepatectomy for colorectal cancer liver metastases. Ann Surg Oncol 2006; 13:353-62; PMID:16474912; http://dx.doi. org/10.1245/ASO.2006.03.060.
23. Li Q, Wang D, Li J, Chen P. Clinicopathological and prognostic significance of HER-2/neu and VEGF expression in colon carcinomas. BMC Cancer 2011; 11:277; PMID:21708009; http://dx.doi. org/10.1186/1471-2407-11-277.
24. Yasuda H, Tanaka K, Saigusa S, Toiyama Y, Koike Y, Okugawa Y, et al. Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer. Oncol Rep 2009; 22:709-17; PMID:19724847.
25. Vermeulen PB, Colpaert C, Salgado R, Royers R, Hellemans H, Van Den Heuvel E, et al. Liver metastases from colorectal adenocarcinomas grow in three patterns with different angiogenesis and desmoplasia. J Pathol 2001; 195:336-42; PMID:11673831; http:// dx.doi.org/10.1002/path.966.
26. Van den Eynden GG, Bird NC, Majeed AW, Van Laere S, Dirix LY, Vermeulen PB. The histological growth pattern of colorectal cancer liver metastases has prognostic value. Clin Exp Metastasis 2012; 29:541-9; PMID:22476470; http://dx.doi.org/10.1007/s10585- 012-9469-1.
27. Rajaganeshan R, Prasad R, Guillou PJ, Chalmers CR, Scott N, Sarkar R, et al. The influence of invasive growth pattern and microvessel density on prognosis in colorectal cancer and colorectal liver metastases. Br J Cancer 2007; 96:1112-7; PMID:17353920; http:// dx.doi.org/10.1038/sj.bjc.6603677.
28. Min BS, Kim NK, Jeong HC, Chung HC. High levels of serum VEGF and TIMP-1 are correlated with colon cancer liver metastasis and intrahepatic recurrence after liver resection. Oncol Lett 2012; 4:123-30; PMID:22807974.
29. Scappaticci FA, Fehrenbacher L, Cartwright T, Hainsworth JD, Heim W, Berlin J, et al. Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab. J Surg Oncol 2005; 91:173-80; PMID:16118771; http://dx.doi. org/10.1002/jso.20301.