메뉴 건너뛰기




Volumn 64, Issue 9, 2010, Pages 402-407

The mechanism underlying the differentiation of human umbilical cord-derived mesenchymal stem cells into myocardial cells induced by 5-azacytidine

Author keywords

5 azacytidine; Dll4 Notch signal pathway; GATA4; Human umbilical cord derived mesenchymal stem cells; Myocardial cells; Nkx2.5

Indexed keywords

AZACITIDINE; CELL DIFFERENTIATION; CELLS, CULTURED; FETAL BLOOD; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION; HOMEODOMAIN PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESENCHYMAL STROMAL CELLS; MYOCYTES, CARDIAC; RECEPTOR, NOTCH1; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TROPONIN I;

EID: 84872070122     PISSN: 00195359     EISSN: 19983654     Source Type: Journal    
DOI: 10.4103/0019-5359.101176     Document Type: Article
Times cited : (18)

References (14)
  • 1
    • 78649643642 scopus 로고    scopus 로고
    • MSCs: Biological characteristics, clinical applications and their outstanding concerns
    • Si YL, Zhao YL, Hao HJ, Fu XB, Han WD. MSCs: Biological characteristics, clinical applications and their outstanding concerns. Ageing Res Rev 2011;10:93-103.
    • (2011) Ageing Res Rev , vol.10 , pp. 93-103
    • Si, Y.L.1    Zhao, Y.L.2    Hao, H.J.3    Fu, X.B.4    Han, W.D.5
  • 2
    • 0034856553 scopus 로고    scopus 로고
    • Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering
    • DOI 10.1046/j.1525-1594.2001.025003187.x
    • Fukuda K. Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. Artif Organs 2001;25:187-93. (Pubitemid 32852966)
    • (2001) Artificial Organs , vol.25 , Issue.3 , pp. 187-193
    • Fukuda, K.1
  • 3
    • 0036491302 scopus 로고    scopus 로고
    • Molecular characterization of regenerated cardiomyocytes derived from adult mesenchymal stem cells
    • Fukuda K. Molecular characterization of regenerated cardiomyocytes derived from adult mesenchymal stem cells. Congenit Anom (Kyoto) 2002;42:1-9. (Pubitemid 34589283)
    • (2002) Congenital Anomalies , vol.42 , Issue.1 , pp. 1-9
    • Fukuda, K.1
  • 4
    • 3042856796 scopus 로고    scopus 로고
    • Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro
    • Xu W, Zhang X, Qian H, Zhu W, Sun X, Hu J, et al. Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro. Exp Biol Med (Maywood) 2004;229:623-31. (Pubitemid 38878907)
    • (2004) Experimental Biology and Medicine , vol.229 , Issue.7 , pp. 623-631
    • Xu, W.1    Zhang, X.2    Qian, H.3    Zhu, W.4    Sun, X.5    Hu, J.6    Zhou, H.7    Chen, Y.8
  • 6
    • 39049189467 scopus 로고    scopus 로고
    • Experimental study of differentiation of mouse bone marrow stromal stem cells into progenitor cardiomyocyte in vitro [In Chinese]
    • Zhang Y, Cai ZJ, Chen RK. Experimental study of differentiation of mouse bone marrow stromal stem cells into progenitor cardiomyocyte in vitro [In Chinese]. Di Yi Jun Yi Da Xue Xue Bao 2005;25:190-4.
    • (2005) Di Yi Jun Yi da Xue Xue Bao , vol.25 , pp. 190-194
    • Zhang, Y.1    Cai, Z.J.2    Chen, R.K.3
  • 7
    • 73649104072 scopus 로고    scopus 로고
    • Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells
    • Cho J, Rameshwar P, Sadoshima J. Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells. J Biol Chem 2009;284:36647-58.
    • (2009) J Biol Chem , vol.284 , pp. 36647-36658
    • Cho, J.1    Rameshwar, P.2    Sadoshima, J.3
  • 8
    • 57049134556 scopus 로고    scopus 로고
    • The Expression of GATA-4 and Nkx2. 5 Gene in the Transformation of Rattus Mesenchymal Stem Cells into Cardiomyocytes [In Chinese]
    • Wu CX, Zhang EY, Yang SY, Ma JY, An Q, Shi YK. The expression of GATA-4 and Nkx2. 5 gene in the transformation of Rattus mesenchymal stem cells into Cardiomyocytes [In Chinese]. Sichuan Da Xue Xue Bao Yi Xue Ban 2008;39:882-5.
    • (2008) Sichuan da Xue Xue Bao Yi Xue Ban , vol.39 , pp. 882-885
    • Wu, C.X.1    Zhang, E.Y.2    Yang, S.Y.3    Ma, J.Y.4    An, Q.5    Shi, Y.K.6
  • 9
    • 80053475507 scopus 로고    scopus 로고
    • Cardiomyocyte-like differentiation of human bone marrow mesenchymal stem cellsafter exposure of 5-azacytidine in vitro
    • Cao F, Niu LL, Meng L, Zhao LX, Zheng M, Yue W, et al. Cardiomyocyte-like differentiation of human bone marrow mesenchymal stem cellsafter exposure of 5-azacytidine in vitro. J Geriatr Cardiol 2004;1:101-7.
    • (2004) J Geriatr Cardiol , vol.1 , pp. 101-107
    • Cao, F.1    Niu, L.L.2    Meng, L.3    Zhao, L.X.4    Zheng, M.5    Yue, W.6
  • 10
    • 1642452660 scopus 로고    scopus 로고
    • Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells
    • DOI 10.1016/j.micinf.2003.10.009
    • Nishitsuji H, Ikeda T, Miyoshi H, Ohashi T, Kannagi M, Masuda T. Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect 2004;6:76-85. (Pubitemid 38114824)
    • (2004) Microbes and Infection , vol.6 , Issue.1 , pp. 76-85
    • Nishitsuji, H.1    Ikeda, T.2    Miyoshi, H.3    Ohashi, T.4    Kannagi, M.5    Masuda, T.6
  • 11
    • 67651121719 scopus 로고    scopus 로고
    • Cardiac differentiation is driven by NKX2.5 and GATA4 nuclear translocation in tissue-specific mesenchymal stem cells
    • Armiñán A, Gandía C, Bartual M, García- Verdugo JM, Lledó E, Mirabet V, et al. Cardiac differentiation is driven by NKX2.5 and GATA4 nuclear translocation in tissue-specific mesenchymal stem cells. Stem Cells Dev 2009;18:907-18.
    • (2009) Stem Cells Dev , vol.18 , pp. 907-918
    • Armiñán, A.1    Gandía, C.2    Bartual, M.3    García- Verdugo, J.M.4    Lledó, E.5    Mirabet, V.6
  • 12
    • 33846699726 scopus 로고    scopus 로고
    • Single-cell-derived mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying cells
    • DOI 10.1016/j.yexcr.2006.11.012, PII S0014482706004769
    • Yamada Y, Sakurada K, Takeda Y, Gojo S, Umezawa A. Single-cell-derived mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying cells. Exp Cell Res 2007;313:698-706. (Pubitemid 46198815)
    • (2007) Experimental Cell Research , vol.313 , Issue.4 , pp. 698-706
    • Yamada, Y.1    Sakurada, K.2    Takeda, Y.3    Gojo, S.4    Umezawa, A.5
  • 13
    • 78649759739 scopus 로고    scopus 로고
    • Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival
    • Li H, Zuo S, He Z, Yang Y, Pasha Z, Wang Y, et al. Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival. Am J Physiol Heart Circ Physiol 2010;299:H1772-81.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Li, H.1    Zuo, S.2    He, Z.3    Yang, Y.4    Pasha, Z.5    Wang, Y.6
  • 14
    • 67349271753 scopus 로고    scopus 로고
    • Notch signaling in cardiac development and disease
    • de la Pompa JL. Notch signaling in cardiac development and disease. Pediatr Cardiol 2009;30:643-50.
    • (2009) Pediatr Cardiol , vol.30 , pp. 643-650
    • De La Pompa, J.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.