Pivotal role of rho-associated kinase 2 in generating the intrinsic circadian rhythm of vascular contractility

Circulation

Volumn 127, Issue 1, 2013, Pages 104-114

  Saito, Toshiro ^a,b   Hirano, Mayumi ^a   Ide, Tomomi ^b   Ichiki, Toshihiro ^a   Koibuchi, Noriyuki ^c   Sunagawa, Kenji ^b   Hirano, Katsuya ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Division of Molecular Cardiology   (Japan)

^c GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

circadian rhythm; muscle, smooth; myosins; vasoconstriction

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CALCIUM; DEXAMETHASONE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MYOSIN LIGHT CHAIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RHO ASSOCIATED KINASE 2; RHO KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DRUG PULSE THERAPY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE SILENCING; HEART MUSCLE CONTRACTILITY; MOUSE; MYOFILAMENT; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA; CELLS, CULTURED; CIRCADIAN RHYTHM; CORONARY VESSELS; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MUSCLE, SMOOTH, VASCULAR; MYOCARDIAL CONTRACTION; MYOSIN LIGHT CHAINS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1; PHOSPHORYLATION; RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; SWINE; VASOCONSTRICTION;

EID: 84872065049     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.135608     Document Type: Article

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