Caspofungin kills Candida albicans by causing both cellular apoptosis and necrosis

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 1, 2013, Pages 326-332

  Hao, Binghua ^a   Cheng, Shaoji ^a   Clancy, Cornelius J ^a   Nguyen, M Hong ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CASPOFUNGIN; DIHYDRORHODAMINE 123; DNA NUCLEOTIDYLEXOTRANSFERASE; FUNGAL ENZYME; HYDROETHIDINE; METACASPASE 1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; APOPTOSIS; ARTICLE; CANDIDA ALBICANS; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DAMAGE; ELECTRON MICROSCOPY; ENZYME ACTIVATION; MINIMUM INHIBITORY CONCENTRATION; NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL;

ANNEXIN A5; ANTIFUNGAL AGENTS; APOPTOSIS; CANDIDA ALBICANS; CELL MEMBRANE; COLONY COUNT, MICROBIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ECHINOCANDINS; ETHIDIUM; IN SITU NICK-END LABELING; INDOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; METHYLENE BLUE; MICROBIAL VIABILITY; MICROSCOPY, ELECTRON; MITOCHONDRIA; NECROSIS; PHOSPHATIDYLSERINES; PROPIDIUM; REACTIVE OXYGEN SPECIES; RHODAMINES;

EID: 84872029205     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01366-12     Document Type: Article

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