Comparison of efficacy and safety of topiramate with gabapentin in migraine prophylaxis: Randomized open label control trial

Journal of the Pakistan Medical Association

Volumn 63, Issue 1, 2013, Pages 3-7

  Zain, Syeda ^a   Khan, Moosa ^b   Alam, Rafique ^c   Zafar, Irfan ^d   Ahmed, Shakil ^b  

^a Saleem Centre North Karachi   (Pakistan)

^b JINNAH POSTGRADUATE MEDICAL CENTRE   (Pakistan)

^c UNIVERSITY OF KARACHI   (Pakistan)

^d HAMDARD UNIVERSITY   (Pakistan)

Author keywords

Gabapentin; Migraine; Prophylaxis; Topiramate

Indexed keywords

GABAPENTIN; TOPIRAMATE;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIGRAINE; OPEN STUDY; PARESTHESIA; RANDOMIZED CONTROLLED TRIAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SIDE EFFECT; SOMNOLENCE; VISUAL ANALOG SCALE; WEIGHT GAIN; WEIGHT REDUCTION;

ADULT; AMINES; ANALGESICS; COHORT STUDIES; CYCLOHEXANECARBOXYLIC ACIDS; FEMALE; FRUCTOSE; GAMMA-AMINOBUTYRIC ACID; HUMANS; MALE; MIDDLE AGED; MIGRAINE DISORDERS; NEUROPROTECTIVE AGENTS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84872027770     PISSN: 00309982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Goadsby PJ, Lipton RB, Ferrari MD. Migraine Current Understanding and treatment. N Eng J Med 2002; 346: 257-70.
2. VukovicV, StrinekaM, Lovrenci?-Huzjan A, DemarinV. Migraine pathophysiology of pain. Med Sci 2009; 33: 33-41.
3. International headache society. The international classification of headache disorder. Cephalalgia 2004; 24(S-1): 8-160.
4. Buse DC, Rupnow MFT, Lipton RB. Assessing and managing all aspects of migraine: migraine attacks, migraine related functional impairment, common comorbidities, and quality of life. Rev 2009; 84: 422-35.
5. Loder E. Triptan therapy in migraine. N Engl J Med 2010; 363: 63-70.
6. Vukovic V, Lovrenci-Huzjan A, Bosnar-Puretic M, Demarin V. The efficacy of gabapentin in migraine prophylaxis an observational open label study. Acta clin Croat 2009; 48: 145-51.
7. Diener HC, Tfelt-Hansen P, Dahlof C, Lainez MJ, Sandrini G, Wang SJ, et al. Topiramate in migraine prophylaxis Results from a placebo controlled trial with propranolol as an active control. J Neurol 2004; 251: 943-50.
8. Kirchmann M. Migraine with aura New understanding from clinical epidemiologic studies. Curr Opin Neurol 2006; 19: 286-93.
9. Lipton RB, Dodick DW, Silberstein SD, Saper JR, Aurora SK, Pearlman SH, Fischell RE, et al. Single-pulse transcranial magnetic stimulation for acute treatment of migraine with aura a randomized double blind parallel-group Sham-controlled trial. Lancet Neurol 2010; 9: 373-80.
10. Pascual J. Recent advances in the pharmacological management of migraine. F1000 Med Rep 2009; 1: 39.
11. Freitag FG, Forde G, Neto W, Wang DZ, Schmitt J, Wu SC, et al. Analysis of pooled data from two pivotal controlled trials on the efficacy of topiramate in the prevention of migraine. J Am Osteopath Assoc 2007; 107: 251-8.
12. Shank RP, Gardocki JF, Streeter AJ, Maryanoff BE, et al. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics and mechanism of action. Epilepsia 2000; 41: S3-9.
13. Akerman S, Goadsby PJ. Topiramate inhibits trigeminovascular activation an intravital microscopy study. Br J Pharmacol 2005; 146: 7-14.
14. Rose MA, Kam PCA. Gabapentin: pharmacology and its use in pain management. Anaesthesia 2002; 57:451-62.
15. Bland JM, Butland BK, Peacock JL, Poloniecki J, Reid F. Statistics Guide for Research Grant Applicants (Online) (Cited 2009). Available from URL: http://wwwusers. york.ac.uk/~mb55/guide/size.htm#compmean.
16. Bussone G, Diener HC, Pfeil J, Schwaler S. Topiramate 100mg/day in migraine prevention: a pooled analysis of double blind randomized controlled trial. Int J Clin Pract 2005; 59: 961-8.
17. Brandes JL, Saper JR, Diamond M, Couch JR, Lewis DW, Schmitt J, et al. MIGR-002 Study Group. Topiramate for migraine prevention: a randomized controlled trial. JAMA 2004; 291: 965-73.
18. Brandes JL, Kudrow DB, Rothrock JF, Rupnow MF, Fairclough DL, Greenberg SJ. Assessing the ability of topiramate to improve the daily activities of patients with migraine. Mayo Clin Proc 2006; 81: 1311-9.
19. Diener HC, Bussone G, Van Oene JC, Lahaye M, Schwalen S, Goodsby PJ; TOPMAT-MIG 201 Study Group. Topiramate reduces headache days in chronic migraine: a randomized, double-blind, placebo-controlled study. Cephalalgia 2007; 27: 814-23.
20. Krymchantowski A, Traves C. Weight variations in patients receiving topiramate, Migraine prophylaxis in a tertiary care setting. Med Gen Med 2004; 6: 48.
21. Johnson BA, Daoud NA. Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patients. Curr Pharm Des 2010; 16: 2103-12.
22. Gupta P, Singh S, Goyal V, Shukla G, Behari M. Low-dose topiramate versus lamotrigine in migraine prophylaxis (the Lotolamp study). Headache 2007; 47:402-12.
23. Di Trapani G, Mei D, Marra C, Mazza S, Capuano A. Gabapentin in the prophylaxis of migraine: a double-blind randomized placebocontrolled study. Clin Ter 2000; 151: 145-8.
24. Diagnosis & management of headache in adults. Scotish inter collegiate guidelines network. November 2008; 107: pp 1-81.
25. Spira PJ, Beran RG. Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebo-controlled study. Neurology 2003; 61: 1753-59.
26. Shaygannejad V, Janghorbani M, Ghorbani A, Ashtary F, Zakizade N, Nasr V. Comparison of the effect of topiramate and sodium valporate in migraine prevention: a randomized blinded crossover study. Headache 2006; 46: 642-8.