Drivers influencing the governance of inter-firm relationships in the biopharmaceutical industry: an empirical survey in the Italian context

Technology Analysis and Strategic Management

Volumn 25, Issue 1, 2013, Pages 107-126

  Billitteri, Carolina ^a   Lo Nigro, Giovanna ^a   Perrone, Giovanni ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

biopharmaceutical industry; governance form; inter firm relationship; survey

Indexed keywords

BIOTECHNOLOGY; MANAGEMENT; PHARMACEUTICAL INDUSTRY; PRODUCT DEVELOPMENT; TECHNOLOGICAL DEVELOPMENT;

ITALY;

EID: 84872027403     PISSN: 09537325     EISSN: 14653990     Source Type: Journal    
DOI: 10.1080/09537325.2012.751010     Document Type: Review

References (59)

1. Bradfield, R. and El-Sayed, H. 2009. Four scenarios for the future of the pharmaceutical industry. Technology Analysis & Strategic Management, 21: 195-212. (doi:10.1080/09537320802625280)
2. Cardinal, L. B. 2001. Technological innovation in the pharmaceutical industry: The use of organizational control in managing research and development. Organization Science, 12(1): 19-36. (doi:10.1287/orsc.12.1.19.10119)
3. Chen, H. and Chen, T. J. 2003. Governance structures in strategic alliances: Transaction cost versus resource-based perspective. Journal of World Business, 38: 1-14. (doi:10.1016/S1090-9516(02)00105-0)
4. Chiesa, V. and Toletti, G. 2004. Network of collaborations for innovation: The case of biotechnology. Technology Analysis & Strategic Management, 16: 73-96. (doi:10.1080/0953732032000175517)
5. Cohen, W. and Levinthal, D. 1990. Absorptive capacity: A new perspective on learning and innovation. Administrative Science Quarterly, 35: 128-52. (doi:10.2307/2393553)
6. Contractor, F. J. and Ra, W. 2002. How knowledge attributes influence alliance governance choices: A theory development note. Journal of International Management, 8: 11-27. (doi:10.1016/S1075-4253(01)00052-7)
7. Danzon, P. M., Epstein, A. and Nicholson, S. 2007. Mergers and acquisitions in the pharmaceutical and biotech industries. Managerial and Decision Economics, 28: 307-28. (doi:10.1002/mde.1343)
8. Das, T. K. and Teng, B. S. 2000. A resource-based theory of strategic alliances. Journal of Management, 26: 31-61.
9. David, R. J. and Han, S. 2004. A systematic assessment of the empirical support for transaction cost economics. Strategic Management Journal, 25: 39-58. (doi:10.1002/smj.359)
10. Deeds, D. L., DeCarolis, D. and Coombs, J. 1999. Dynamic capabilities and new product development in high technology ventures: An empirical analysis of new biotechnology firms. Journal of Business Venturing, 15: 211-29. (doi:10.1016/S0883-9026(98)00013-5)
11. Delerue, H. 2004. Relational risk perception and alliance management in French biotechnology SMEs. European Business Review, 17: 532-46. (doi:10.1108/09555340510630563)
12. DiMasi, J. A. 2001. Risk in new drug development: Approval success rates for investigational drugs. Clinical Pharmacology and Therapeutics, 69: 297-307. (doi:10.1067/mcp.2001.115446)
13. DiMasi, J. A., Hansen, R. W. and Grabowski, H. G. 2003. The price of innovation: New estimates of drug development cost. Journal of Health Economics, 22: 151-85. (doi:10.1016/S0167-6296(02)00126-1)
14. Eisenhardt, K. M. and Martin, J. A. 2000. Dynamic capabilities: what are they?. Strategic Management Journal, 21: 1105-21. (doi:10.1002/1097-0266(200010/11)21:10/11<1105::AID-SMJ133>3.0.CO;2-E)
15. Folta, T. 1998. Governance and uncertainty: The trade-off between administrative control and commitment. Strategic Management Journal, 19: 1007-28. (doi:10.1002/(SICI)1097-0266(1998110)19:11<1007::AID-SMJ999>3.0.CO;2-8)
16. Foss, N. J. and Roemer, E. 2010. Real options, resources and transaction costs: Advancing the strategic theory of the firm. International Journal of Strategic Change Management, 2: 73-92. (doi:10.1504/IJSCM.2010.032523)
17. Goozner, M. 2004. The $800 million pill: The truth behind the cost of new drugs, Berkeley, CA: University of California Press.
18. Gulati, R. 1995. Does familiarity breed trust? The implications of repeated choice for contractual ties in alliances. Academy of Management Journal, 38: 85-112. (doi:10.2307/256729)
19. Gulati, R., Nohria, N. and Zaheer, A. 2000. Strategic networks. Strategic Management Journal, 21: 203-15. (doi:10.1002/(SICI)1097-0266(200003)21:3<203::AID-SMJ102>3.0.CO;2-K)
20. Gulati, R. and Singh, H. 1998. The architecture of cooperation: Managing coordination uncertainty and interdependence in strategic alliances. Administrative Science Quarterly, 43: 781-814. (doi:10.2307/2393616)
21. Hart, O. D. and More, J. 1990. Property rights and the nature of the firm. The Journal of Political Economy, 98: 1119-58. (doi:10.1086/261729)
22. Higgins, M. J. and Rodriguez, D. 2006. The outsourcing of R&D through acquisitions in the pharmaceutical industry. Journal of Financial Economics, 80: 351-83. (doi:10.1016/j.jfineco.2005.04.004)
23. Janney, J. J. and Dess, G. G. 2004. Can real-options analysis improve decision-making? Promises and pitfalls. Academy of Management Executive, 18(4): 60-75. (doi:10.5465/AME.2004.15268687)
24. Klein, B. and Murphy, K. 1997. Vertical integration as a self-enforcing contractual arrangement. American Economic Review, 87: 415-20.
25. Kogut, B. 1991. Joint ventures and the option to expand and acquire. Management Science, 37: 19-33. (doi:10.1287/mnsc.37.1.19)
26. Kogut, B. and Zander, U. 1992. Knowledge of the firm, combinative capabilities, and the replication of technology. Organization Science, 3: 383-97. (doi:10.1287/orsc.3.3.383)
27. Lambe, C. J. and Spekman, R. E. 1997. Alliances, external technology acquisition, and discontinuous technology change. Journal of Product Innovation Management, 14: 102-16. (doi:10.1016/S0737-6782(96)00077-X)
28. Leiblein, M. J. 2003. The choice of organizational governance form and performance: Predictions from transaction cost, resource-based, and real option theories. Journal of Management, 29: 937-61.
29. Leiblein, M. J. and Miller, D. J. 2003. An empirical examination of transaction and firm-level influences on the vertical boundaries of the firm. Strategic Management Journal, 24: 839-59. (doi:10.1002/smj.340)
30. Leiblein, M. J., Reuer, J. J. and Dalsace, F. 2002. Do make or buy decisions matter? The influence of governance on technological performance. Strategic Management Journal, 23: 817-33. (doi:10.1002/smj.259)
31. Lo Nigro, G. and Abbate, L. 2010. Risk assessment and profit sharing in business networks. International Journal of Production Economics, 131(1): 234-41. (doi:10.1016/j.ijpe.2009.08.014)
32. Madhok, A. and Osegowitsch, T. 2000. The international biotechnology industry: A dynamic capabilities perspective. Journal of International Business Studies, 31: 325-35. (doi:10.1057/palgrave.jibs.8490909)
33. Mahoney, J. T. 1992. The choice of organizational form: Vertical financial ownership versus other methods of vertical integration. Strategic Management Journal, 13: 559-84. (doi:10.1002/smj.4250130802)
34. Myers, S. 1977. Determinants of capital borrowing. Journal of Financial Economics, 5: 147-75. (doi:10.1016/0304-405X(77)90015-0)
35. McCutchen, W. W. and Swamidass, P. M. 2004. Motivations for strategic alliances in the pharmaceutical/biotech industry: Some new findings. Journal of High Technology Management Research, 15: 197-214. (doi:10.1016/j.hitech.2004.03.003)
36. O'Dwyer, M. and O'Flynn, E. 2005. MNC-SME strategic alliances-A model framing knowledge value as the primary predictor of governance modal choice. Journal of International Management, 11: 397-416. (doi:10.1016/j.intman.2005.06.006)
37. Oxley, J. E. 1997. Appropriability hazards and governance in strategic alliances: A transaction cost approach. The Journal of Law, Economics, Organization, 13: 387-409. (doi:10.1093/oxfordjournals.jleo.a023389)
38. Parkhe, A. 1993. Strategic alliance structuring: A game theoretic and transaction cost examination of interfirm cooperation. The Academy of Management Journal, 36: 794-829. (doi:10.2307/256759)
39. Patelli, A. G. 2009. Decision making on governance of strategic technology alliances. Management Decision, 47: 246-70. (doi:10.1108/00251740910938902)
40. Pisano, G. P. 1990. The R&D boundaries of the firm: An empirical analysis. Special issue. Administrative Science Quarterly, 35(1): 153-76. (doi:10.2307/2393554)
41. Pisano, G. P. 2000. "In search of dynamic capabilities: The origins of R&D competence in biopharmaceuticals". In The Nature and dynamics of organizational capabilities, Edited by: Dosi, G., Nelson, R. R. and Winter, S. G. 129-54. Oxford: Oxford University Press.
42. Pisano, G. P. 2006. Science business, Cambridge, MA: Harvard Business School Press.
43. Ring, P. S. and Van de Ven, A. H. 1994. Developmental processes of cooperative inter-organizational relationships. Academy of Management Review, 19: 90-118.
44. Rosiello, A. 2007. At the interfaces of governance and competence perspectives: Discussing organizational choices in the Scottish biotechnology cluster. Technology Analysis & Strategic Management, 19: 45-68. (doi:10.1080/09537320601065308)
45. Rothaermel, F. T. 2001a. Incubent's advantage through exploiting complementary assets via interfirm cooperation. Strategic Management Journal, 22: 687-99. (doi:10.1002/smj.180)
46. Rothaermel, F. T. 2001b. Complementary assets, strategic alliances, and the incumbent's advantage: An empirical study of industry and firm effects in the biopharmaceutical industry. Research Policy, 30: 1235-51. (doi:10.1016/S0048-7333(00)00142-6)
47. Sabatier, V., Mangematin, V. and Rousselle, T. 2010. Orchestrating networks in the biopharmaceutical industry: Small hub firms can do it. Production Planning and Control, 21: 218-28. (doi:10.1080/09537280903441971)
48. Santoro, M. D. and McGill, J. P. 2005. The effect of uncertainty and asset co-specialization on governance in biotechnology alliances. Strategic Management Journal, 26: 1261-69. (doi:10.1002/smj.506)
49. Steensma, H. K. and Fairbank, J. F. 1999. Internalizing external technology: A model of governance mode choice and an empirical assessment. The Journal of High Technology Management Research, 10: 1-35. (doi:10.1016/S1047-8310(99)80001-7)
50. Stuart, T. E., Hoang, H. and Hybels, R. C. 1999. Interorganizational endorsements and the performance of entrepreneurial ventures. Administrative Science Quarterly, 44: 315-49. (doi:10.2307/2666998)
51. Sutcliffe, K. M. and Zaheer, A. 1998. Uncertainty in the transaction environment: An empirical test. Strategic Management Journal, 19: 1-23. (doi:10.1002/(SICI)1097-0266(199801)19:1<1::AID-SMJ938>3.0.CO;2-5)
52. Tripsas, M. 1997. Unravelling the process of creative destruction: Complementary assets and incumbent survival in the typesetter industry. Strategic Management Journal, 18: 119-42. (doi:10.1002/(SICI)1097-0266(199707)18:1+<119::AID-SMJ921>3.3.CO;2-S)
53. Tushman, M. L. and Anderson, P. C. 1986. Technological discontinuities and organizational environments. Administrative Science Quarterly, 31: 439-65. (doi:10.2307/2392832)
54. Van de Vrande, V., Vanhaverbeke, W. and Duysters, G. 2009. External technology sourcing: The effect of uncertainty of governance mode choice. Journal of Business Venturing, 24: 62-80. (doi:10.1016/j.jbusvent.2007.10.001)
55. Vanhaverbeke, W., Duysters, G. and Noorderhaven, N. 2002. External technology sourcing through alliances or acquisitions: An analysis of the application-specific integrated circuits industry. Organization Science, 13: 714-33. (doi:10.1287/orsc.13.6.714.496)
56. Williamson, O. E. 1979. Transaction cost economics: The governance of contractual relations. Journal of Law and Economics, 22: 233-61. (doi:10.1086/466942)
57. Williamson, O. E. 1985. The economic institutions of capitalism, New York: Free Press.
58. Williamson, O. E. 1991. Comparative economic organization: The analysis of discrete structural alternatives. Administrative Science Quarterly, 36: 269-96. (doi:10.2307/2393356)
59. Zollo, M., Reuer, J. and Singh, H. 2002. Interorganizational routines and performance in strategic alliances. Organizational Science, 13: 701-13. (doi:10.1287/orsc.13.6.701.503)