Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension

Respiratory Research

Volumn 14, Issue 1, 2013, Pages

  Pfarr, Nicole ^a,b   Fischer, Christine ^a   Ehlken, Nicola ^b   Becker Grünig, Tabea ^b   López González, Vanesa ^c   Gorenflo, Matthias ^a   Hager, Alfred ^d   Hinderhofer, Katrin ^a   Miera, Oliver ^e   Nagel, Christian ^b   Schranz, Dietmar ^f   Grünig, Ekkehard ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^f JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Bone morphogenetic protein receptor 2; Children; Congenital heart disease; Genetics; Pulmonary hypertension

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR LIKE KINASE 1; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; ENDOGLIN; MESSENGER RNA; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD9 PROTEIN; UNCLASSIFIED DRUG; ACTIVIN RECEPTOR 2; ACVRL1 PROTEIN, HUMAN; BMPR2 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; LEUKOCYTE ANTIGEN;

ARTICLE; CHILDHOOD DISEASE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONGENITAL HEART DISEASE; CONGENITAL HEART DISEASE ASSOCIATED PULMONARY ARTERY HYPERTENSION; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENE MUTATION; GENETIC ANALYSIS; HEMODYNAMICS; HERITABLE PULMONARY ARTERIAL HYPERTENSION; HUMAN; MALE; NONSENSE MUTATION; PEDIGREE; PROSPECTIVE STUDY; PULMONARY HYPERTENSION; ADOLESCENT; CHI SQUARE DISTRIBUTION; CHILD; COMPARATIVE STUDY; CONGENITAL HEART MALFORMATION; GENETIC PREDISPOSITION; GENETICS; HEREDITY; INFANT; MUTATION; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHENOTYPE; PRESCHOOL CHILD;

ACTIVIN RECEPTORS, TYPE II; ADOLESCENT; ANTIGENS, CD; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEART DEFECTS, CONGENITAL; HEMODYNAMICS; HEREDITY; HUMANS; HYPERTENSION, PULMONARY; INFANT; MALE; MUTATION; PEDIGREE; PHENOTYPE; PROSPECTIVE STUDIES; RECEPTORS, CELL SURFACE;

MLCS; MLOWN;

EID: 84872021292     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-14-3     Document Type: Article

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