Retinal fundus imaging in mouse models of retinal diseases

Methods in Molecular Biology

Volumn 935, Issue , 2013, Pages 41-67

  Alex, Anne F ^a   Heiduschka, Peter ^a   Eter, Nicole ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Choroidal neovascularization; Confocal scanning laser ophthalmoscopy; Fluorescein angiography; Indocyanine green angiography; Optical coherence tomography; Retinal imaging; Retinal neovascularization

Indexed keywords

ANIMAL; ARTICLE; DISEASE MODEL; EQUIPMENT DESIGN; EYE FUNDUS; FLUORESCENCE ANGIOGRAPHY; INSTRUMENTATION; METHODOLOGY; MOUSE; OPHTHALMOSCOPE; OPHTHALMOSCOPY; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; RETINA; RETINA BLOOD VESSEL; RETINA DISEASE; RETINA NEOVASCULARIZATION;

ANIMALS; DISEASE MODELS, ANIMAL; EQUIPMENT DESIGN; FLUORESCEIN ANGIOGRAPHY; FUNDUS OCULI; MICE; OPHTHALMOSCOPES; OPHTHALMOSCOPY; RETINA; RETINAL DISEASES; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; TOMOGRAPHY, OPTICAL COHERENCE;

ANIMALIA; MUS;

EID: 84871951394     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-080-9-3     Document Type: Article

References (46)

1. van Leeuwen R et al (2003) Epidemiology of age-related maculopathy: A review Eur J Epidemiol 18:845-854 (Pubitemid 37169020)
2. Grossniklaus HE et al (2010) Animal models of choroidal and retinal neovascularization. Prog Retin Eye Res 29:500-519
3. Barber AJ (2003) A new view of diabetic retinopathy: A neurodegenerative disease of the eye. Prog Neuropsychopharmacol Biol Psychiatry 27:283-290 (Pubitemid 36351495)
4. Joussen AM et al (2003) Molecular mechanisms of vasculogenesis and angiogenesis. What regulates vascular growth? Ophthalmologe 100: 284-291 (Pubitemid 36718082)
5. Sharp PF, Manivannan A (1997) The scanning laser ophthalmoscope. Phys Med Biol 42: 951-966 (Pubitemid 27263510)
6. Paques M et al (2007) Panretinal, high-resolution color photography of the mouse fundus. Invest Ophthalmol Vis Sci 48:2769-2774 (Pubitemid 351261232)
7. Bermudez MA et al (2011) Time course of cold cataract development in anesthetized mice. Curr Eye Res 36:278-284
8. Terman A (2006) Catabolic insuf fi ciency and aging. Ann N Y Acad Sci 1067:27-36
9. Brunk UT, Terman A (2002) Lipofuscin: Mechanisms of age-related accumulation and in fl uence on cell function. Free Radic Biol Med 33:611-619 (Pubitemid 35245833)
10. Seehafer SS, Pearce DA (2006) You say lipofuscin, we say ceroid: De fi ning auto fl uorescent storage material. Neurobiol Aging 27: 576-588 (Pubitemid 43290526)
11. Eldred GE et al (1982) Lipofuscin: Resolution of discrepant fl uorescence data. Science 216: 757-759 (Pubitemid 12041780)
12. Marmorstein AD et al (2002) Spectral pro fi ling of auto fl uorescence associated with lipofuscin, Bruch's Membrane, and sub-RPE deposits in normal and AMD eyes. Invest Ophthalmol Vis Sci 43:2435-2441 (Pubitemid 34700679)
13. Eldred GE, Lasky MR (1993) Retinal age pigments generated by self-assembling lysosomotropic detergents. Nature 361:724-726 (Pubitemid 23070479)
14. Sparrow JR et al (1999) A2E, a lipofuscin fl uorophore, in human retinal pigmented epithelial cells in culture. Invest Ophthalmol Vis Sci 40:2988-2995 (Pubitemid 29521615)
15. Schmitz-Valckenberg S et al (2008) Fundus auto fl uorescence imaging: Review and perspectives. Retina 28:385-409 (Pubitemid 351354940)
16. Bridges CD (1977) Rhodopsin regeneration in rod outer segments: Utilization of 11-cis retinal and retinol. Exp Eye Res 24:571-580 (Pubitemid 8135755)
17. Jaffe GJ, Caprioli J (2004) Optical coherence tomography to detect and manage retinal disease and glaucoma. Am J Ophthalmol 137:156-169 (Pubitemid 38045202)
18. Hawes NL et al (1999) Mouse fundus photography and angiography: A catalogue of normal and mutant phenotypes. Mol Vis 5:22
19. Chang B et al (2002) Retinal degeneration mutants in the mouse. Vision Res 42:517-525 (Pubitemid 34169709)
20. Eter N et al (2008) In vivo visualization of dendritic cells, macrophages, and microglial cells responding to laser-induced damage in the fundus of the eye. Invest Ophthalmol Vis Sci 49:3649-3658
21. Tobe T et al (1998) Evolution of neovascularization in mice with overexpression of vascular endothelial growth factor in photoreceptors. Invest Ophthalmol Vis Sci 39:180-188 (Pubitemid 28040477)
22. Smith LE et al (1994) Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci 35:101-111 (Pubitemid 24046832)
23. Spilsbury K et al (2000) Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization. Am J Pathol 157:135-144 (Pubitemid 30641731)
24. Schmack I et al (2009) Modulation of choroidal neovascularization by subretinal injection of retinal pigment epithelium and polystyrene microbeads. Mol Vis 15:146-161
25. Shen D et al (2006) Exacerbation of retinal degeneration and choroidal neovascularization induced by subretinal injection of matrigel in CCL2/MCP-1-de fi cient mice. Ophthalmic Res 38:71-73 (Pubitemid 43325897)
26. Giove TJ et al (2009) Increased neuronal nitric oxide synthase activity in retinal neurons in early diabetic retinopathy. Mol Vis 15:2249-2258
27. Zhu SS et al (2011) Wld (S) protects against peripheral neuropathy and retinopathy in an experimental model of diabetes in mice. Diabetologia 54(9):2440-2450
28. Kern TS et al (2010) Validation of structural and functional lesions of diabetic retinopathy in mice. Mol Vis 16:2121-2131
29. Larina IV et al (2009) A membrane associated mCherry fl uorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development. Anat Rec (Hoboken) 292:333-341
30. Poche RA et al (2009) The Flk1-myr::mCherry mouse as a useful reporter to characterize multiple aspects of ocular blood vessel development and disease. Dev Dyn 238:2318-2326
31. Jung S et al (2000) Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fl uorescent protein reporter gene insertion. Mol Cell Biol 20:4106-4114 (Pubitemid 30314508)
32. Kuziel WA et al (1997) Severe reduction in leukocyte adhesion and monocyte extravasation in mice de fi cient in CC chemokine receptor 2. Proc Natl Acad Sci USA 94:12053-12058 (Pubitemid 27467841)
33. Ambati J et al (2003) An animal model of agerelated macular degeneration in senescent Ccl-2-or Ccr-2-de fi cient mice. Nat Med 9:1390-1397 (Pubitemid 37466188)
34. Tuo J et al (2007) Murine ccl2/cx3cr1 de fi ciency results in retinal lesions mimicking human age-related macular degeneration. Invest Ophthalmol Vis Sci 48:3827-3836 (Pubitemid 351261124)
35. Takeda A et al (2009) CCR3 is a target for agerelated macular degeneration diagnosis and therapy. Nature 460:225-230
36. Malek G et al (2005) Apolipoprotein E alleledependent pathogenesis: A model for agerelated retinal degeneration. Proc Natl Acad Sci USA 102:11900-11905 (Pubitemid 41170822)
37. Okamoto N et al (1997) Transgenic mice with increased expression of vascular endothelial growth factor in the retina: A new model of intraretinal and subretinal neovascularization. Am J Pathol 151:281-291
38. Heckenlively JR et al (2003) Mouse model of subretinal neovascularization with choroidal anastomosis. Retina 23:518-522 (Pubitemid 37071966)
39. Won J et al (2011) Mouse model resources for vision research. J Ophthalmol 2011:391384
40. Huber G et al (2009) Spectral domain optical coherence tomography in mouse models of retinal degeneration. Invest Ophthalmol Vis Sci 50:5888-5895
41. Kohler K et al (1997) Animal models for retinitis pigmentosa research. Klin Monbl Augenheilkd 211:84-93 (Pubitemid 27398089)
42. Van Hooser JP et al (2000) Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness. Proc Natl Acad Sci USA 97:8623-8628 (Pubitemid 30639723)
43. Seeliger MW et al (2005) In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy. Vision Res 45:3512-3519 (Pubitemid 41737379)
44. de la Cera EG et al (2006) Optical aberrations in the mouse eye. Vision Res 46:2546-2553
45. Marneros AG et al (2007) Endogenous endostatin inhibits choroidal neovascularization. FASEB J 21:3809-3818 (Pubitemid 350232338)
46. Sheets KG et al (2010) Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse. Mol Vis 16:320-329