Omentin-1, a new adipokine, promotes apoptosis through regulating Sirt1-dependent p53 deacetylation in hepatocellular carcinoma cells

European Journal of Pharmacology

Volumn 698, Issue 1-3, 2013, Pages 137-144

  Zhang, Yuan Yuan ^a   Zhou, Li Ming ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Acetylation; Adipokine; HCC cells; Omentin 1; p53; Sirt1

Indexed keywords

ADIPOCYTOKINE; CASPASE 3; HISTONE DEACETYLASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OMENTIN 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; RECOMBINANT OMENTIN 1; SIRT1 DEACETYLASE; SIRTUIN 1; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL STRAIN HUH 7; CELL VIABILITY; CONTROLLED STUDY; DEACETYLATION; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYLATION; ADIPOKINES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOKINES; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GPI-LINKED PROTEINS; HEP G2 CELLS; HUMANS; INTRACELLULAR SPACE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LECTINS; LIVER NEOPLASMS; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; SIRTUIN 1; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84871923072     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.11.016     Document Type: Article

References (46)

1. I. Barone, S. Catalano, L. Gelsomino, S. Marsico, C. Giordano, S. Panza, D. Bonofiglio, G. Bossi, K.R. Covington, S.A. Fuqua, and S. Ando Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells Cancer Res. 72 2012 1416 1427
2. T.Q. Bi, and X.M. Che Nampt/PBEF/visfatin and cancer Cancer Biol. Ther. 10 2010 119 125
3. F. Bianchini, R. Kaaks, and H. Vainio Overweight, obesity, and cancer risk Lancet Oncol. 3 2002 565 574 (Pubitemid 34993644)
4. E.E. Calle, C. Rodriguez, K. Walker-Thurmond, and M.J. Thun Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults N. Engl. J. Med. 348 2003 1625 1638 (Pubitemid 36459468)
5. G.N. Chaldakov, I.S. Stankulov, M. Hristova, and P.I. Ghenev Adipobiology of disease: adipokines and adipokine-targeted pharmacology Curr. Pharm. Des. 9 2003 1023 1031 (Pubitemid 36443203)
6. C.M. de Souza Batista, R.Z. Yang, M.J. Lee, N.M. Glynn, D.Z. Yu, J. Pray, K. Ndubuizu, S. Patil, A. Schwartz, M. Kligman, S.K. Fried, D.W. Gong, A.R. Shuldiner, T.I. Pollin, and J.C. McLenithan Omentin plasma levels and gene expression are decreased in obesity Diabetes 56 2007 1655 1661 (Pubitemid 46842600)
7. G. Fava, G. Alpini, C. Rychlicki, S. Saccomanno, S. DeMorrow, L. Trozzi, C. Candelaresi, J. Venter, A. Di Sario, M. Marzioni, I. Bearzi, S. Glaser, D. Alvaro, L. Marucci, H. Francis, G. Svegliati-Baroni, and A. Benedetti Leptin enhances cholangiocarcinoma cell growth Cancer Res 68 2008 6752 6761
8. D.R. Green, and G. Kroemer Cytoplasmic functions of the tumour suppressor p53 Nature 458 2009 1127 1130
9. O. Gualillo, J.R. Gonzalez-Juanatey, and F. Lago The emerging role of adipokines as mediators of cardiovascular function: physiologic and clinical perspectives Trends Cardiovasc Med. 17 2007 275 283 (Pubitemid 350087698)
10. B.S. Habeeb, J. Kitayama, and H. Nagawa Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells Cancer Sci. 102 2011 999 1006
11. G. Han, L. Wang, R. Zhao, Z. Yue, X. Zhou, X. Hu, Y. Cao, D. Dai, and J. Liu Leptin promotes human glioblastoma growth through activating signal transducers and activators of transcription 3 signaling Brain Res. Bull. 87 2012 274 279
12. M. Ishikawa, J. Kitayama, S. Kazama, T. Hiramatsu, K. Hatano, and H. Nagawa Plasma adiponectin and gastric cancer Clin. Cancer Res. 11 2005 466 472 (Pubitemid 40116868)
13. L.J. Juan, W.J. Shia, M.H. Chen, W.M. Yang, E. Seto, Y.S. Lin, and C.W. Wu Histone deacetylases specifically down-regulate p53-dependent gene activation J. Biol. Chem. 275 2000 20436 20443 (Pubitemid 30457621)
14. T.J. Key, N.E. Allen, E.A. Spencer, and R.C. Travis The effect of diet on risk of cancer Lancet 360 2002 861 868 (Pubitemid 35257961)
15. T. Komiya, Y. Tanigawa, and S. Hirohashi Cloning of the novel gene intelectin, which is expressed in intestinal paneth cells in mice Biochem. Biophys. Res. Commun. 251 1998 759 762 (Pubitemid 28512784)
16. J.P. Kruse, and W. Gu Modes of p53 regulation Cell 137 2009 609 622
17. S.C. Larsson, and A. Wolk Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies Br. J. Cancer 97 2007 1005 1008 (Pubitemid 47519294)
18. E.C. Lazcano-Ponce, J.F. Miquel, N. Munoz, R. Herrero, C. Ferrecio, II Wistuba, P. Alonso de Ruiz, G. Aristi Urista, and F. Nervi Epidemiology and molecular pathology of gallbladder cancer CA Cancer J. Clin. 51 2001 349 364 (Pubitemid 34232782)
19. Z.Y. Li, P. Wang, and C.Y. Miao Adipokines in inflammation, insulin resistance and cardiovascular disease Clin. Exp. Pharmacol. Physiol. 38 2011 888 896
20. R. Liu, X. Wang, and P. Bu Omentin-1 is associated with carotid atherosclerosis in patients with metabolic syndrome Diabetes Res. Clin. Pract. 93 2011 21 25
21. J. Luo, A.Y. Nikolaev, S. Imai, D. Chen, F. Su, A. Shiloh, L. Guarente, and W. Gu Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 107 2001 137 148 (Pubitemid 33035941)
22. J. Luo, F. Su, D. Chen, A. Shiloh, and W. Gu Deacetylation of p53 modulates its effect on cell growth and apoptosis Nature 408 2000 377 381
23. A.P. Mogal, R. van der Meer, P.S. Crooke, and S.A. Abdulkadir Haploinsufficient prostate tumor suppression by Nkx3.1: a role for chromatin accessibility in dosage-sensitive gene regulation J. Biol. Chem. 282 2007 25790 25800 (Pubitemid 47372777)
24. J.M. Moreno-Navarrete, F. Ortega, A. Castro, M. Sabater, W. Ricart, and J.M. Fernandez-Real Circulating omentin as a novel biomarker of endothelial dysfunction Obesity (Silver Spring) 19 2011 1552 1559
25. S. Otake, H. Takeda, Y. Suzuki, T. Fukui, S. Watanabe, K. Ishihama, T. Saito, H. Togashi, T. Nakamura, Y. Matsuzawa, and S. Kawata Association of visceral fat accumulation and plasma adiponectin with colorectal adenoma: evidence for participation of insulin resistance Clin. Cancer Res. 11 2005 3642 3646 (Pubitemid 40685579)
26. H.Y. Pan, L. Guo, and Q. Li Changes of serum omentin-1 levels in normal subjects and in patients with impaired glucose regulation and with newly diagnosed and untreated type 2 diabetes Diabetes Res. Clin. Pract. 88 2010 29 33
27. S.T. Patel, T. Mistry, J.E. Brown, J.E. Digby, R. Adya, K.M. Desai, and H.S. Randeva A novel role for the adipokine visfatin/pre-B cell colony-enhancing factor 1 in prostate carcinogenesis Peptides 31 2010 51 57
28. N.K. Saxena, P.P. Fu, A. Nagalingam, J. Wang, J. Handy, C. Cohen, M. Tighiouart, D. Sharma, and F.A. Anania Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma Gastroenterology 139 2010 1762 1773 1773 e1761-1765
29. A. Schaffler, M. Neumeier, H. Herfarth, A. Furst, J. Scholmerich, and C. Buchler Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue Biochim. Biophys. Acta 1732 2005 96 102 (Pubitemid 43267310)
30. E. Schmitt, A.T. Sane, A. Steyaert, G. Cimoli, and R. Bertrand The Bcl-xL and Bax-alpha control points: modulation of apoptosis induced by cancer chemotherapy and relation to TPCK-sensitive protease and caspase activation Biochem. Cell. Biol. 75 1997 301 314 (Pubitemid 127733181)
31. F.J. Shang, J.P. Wang, X.T. Liu, Q.S. Zheng, Y.S. Xue, B. Wang, and L.Y. Zhao Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome Biomarkers 16 2011 657 662
32. D. Sharma, J. Wang, P.P. Fu, S. Sharma, A. Nagalingam, J. Mells, J. Handy, A.J. Page, C. Cohen, F.A. Anania, and N.K. Saxena Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis Hepatology 52 2010 1713 1722
33. R. Shibata, R. Takahashi, Y. Kataoka, K. Ohashi, N. Ikeda, S. Kihara, T. Murohara, and N. Ouchi Association of a fat-derived plasma protein omentin with carotid artery intima-media thickness in apparently healthy men Hypertens. Res. 34 2012 1309 1312
34. R.V. Sionov, and Y. Haupt The cellular response to p53: the decision between life and death Oncogene 18 1999 6145 6157
35. S.C. Sorli, S. Le Gonidec, B. Knibiehler, and Y. Audigier Apelin is a potent activator of tumour neoangiogenesis Oncogene 26 2007 7692 7699 (Pubitemid 350224216)
36. B.K. Tan, R. Adya, S. Farhatullah, K.C. Lewandowski, P. O'Hare, H. Lehnert, and H.S. Randeva Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose Diabetes 57 2008 801 808
37. B.K. Tan, R. Adya, and H.S. Randeva Omentin: a novel link between inflammation, diabesity, and cardiovascular disease Trends Cardiovasc. Med. 20 2010 143 148
38. H. Vaziri, S.K. Dessain, E. Ng Eaton, S.I. Imai, R.A. Frye, T.K. Pandita, L. Guarente, and R.A. Weinberg hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase Cell 107 2001 149 159 (Pubitemid 33035942)
39. P. Wang, Y.F. Guan, H. Du, Q.W. Zhai, D.F. Su, and C.Y. Miao Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia Autophagy 8 2012 77 87
40. P. Wang, W.W. Tian, J. Song, Y.F. Guan, and C.Y. Miao Deficiency of NG2(+) cells contributes to the susceptibility of stroke-prone spontaneously hypertensive rats CNS Neurosci. Ther. 17 2011 327 332
41. P. Wang, T.Y. Xu, Y.F. Guan, D.F. Su, G.R. Fan, and C.Y. Miao Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide Cardiovasc. Res. 81 2009 370 380
42. P. Wang, T.Y. Xu, Y.F. Guan, W.W. Tian, B. Viollet, Y.C. Rui, Q.W. Zhai, D.F. Su, and C.Y. Miao Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway Ann. Neurol. 69 2011 360 374
43. P. Wang, F.J. Yang, H. Du, Y.F. Guan, T.Y. Xu, X.W. Xu, D.F. Su, and C.Y. Miao Involvement of leptin receptor (LepRb)-STAT3 signaling pathway in brain FTO downregulation during energy restriction Mol. Med. 17 2011 523 532
44. P. Wang, R.Y. Zhang, J. Song, Y.F. Guan, T.Y. Xu, H. Du, B. Viollet, and C.Y. Miao Loss of AMP-activated protein kinase-alpha2 impairs the insulin-sensitizing effect of calorie restriction in skeletal muscle Diabetes 61 2012 1051 1061
45. P. Yan, D. Liu, M. Long, Y. Ren, J. Pang, and R. Li Changes of serum omentin levels and relationship between omentin and adiponectin concentrations in type 2 diabetes mellitus Exp. Clin. Endocrinol. Diabetes 119 2011 257 263
46. R.Z. Yang, M.J. Lee, H. Hu, J. Pray, H.B. Wu, B.C. Hansen, A.R. Shuldiner, S.K. Fried, J.C. McLenithan, and D.W. Gong Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action Am. J. Physiol. Endocrinol. Metab. 290 2006 E1253 1261