Variable cardiac 18FDG patterns seen in oncologic positron emission tomography computed tomography importance for differentiating normal physiology from cardiac and paracardiac disease

Journal of Thoracic Imaging

Volumn 27, Issue 4, 2012, Pages 263-268

  Maurer, Alan H ^a   Burshteyn, Mark ^a   Adler, Lee P ^a   Gaughan, John P ^a   Steiner, Robert M ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fluorine 18 fluorodeoxyglucose; Myocardial metabolism; Positron emission tomography

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADULT; ARTICLE; CANCER PATIENT; CARDIAC IMAGING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; FEMALE; HEART; HEART CONTRACTION; HEART DISEASE; HEART VENTRICLE SEPTUM; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; SCINTISCANNING; THORAX TUMOR;

ADULT; FEMALE; FLUORODEOXYGLUCOSE F18; HEART; HEART DISEASES; HUMANS; MALE; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; THORACIC NEOPLASMS; YOUNG ADULT;

EID: 84871916355     PISSN: 08835993     EISSN: 15360237     Source Type: Journal    
DOI: 10.1097/RTI.0b013e3182176675     Document Type: Article

References (23)

1. Choi Y, Brunken R, Hawkins R, et al. Factors affecting myocardial 2-[F-18]fluoro-2-deoxy-D-glucose uptake in positron emission tomography studies of normal humans. Eur J Nucl Med. 1992;20:308-318.
2. Ding H, Sjoai Y, Wang J, et al. The influences of blood glucose and duration of fasting on myocardial glucose uptake of [18F]fluoro-2-depxu-D- glucose. Nucl Med Commun. 2002;23:961-965.
3. Inglese E, Leva L, Matheoud R, et al. Spatial and temporal heterogeneity of regional myocardial uptake in patients without heart disease under fasting conditions on repeated whole-body 18F-FDG PET/CT. J Nucl Med. 2007;48:1662-1669.
4. Kaneta T, Hakamatsuka T, Takanami K, et al. Evaluation of the relationship between physiological FDG uptake in the heart and age, blood glucose level, fasting period, and hospitalization. Ann Nucl Med. 2006;3:203-208.
5. Khandani AH, Isasi CR, Blaufox D. Intra-individual variability of cardiac uptake on serial whole-body 18F-FDG PET. Nucl Med Comm. 2005;26:787-791.
6. Williams G, Kolodny G. Suppression of myocardial 18F-FDG uptake by preparing patients with a high-fat, low-carbohydrate diet. AJR. 2008;190:151-156.
7. Zophel K, Kotzerke J. High intraindividual variability of global myocardial 18F-FDG uptake over time [comment]. J Nucl Med. 2008;49:1570; author reply 1570-1571.
8. Gropler R, Siegel A, Moerlein S, et al. Nonuniformity in myocardial accumulation of fluorine-18-deoxyglucose in normal fasted humans. J Nucl Med. 1990;31:1749-1756.
9. Jingu K, Kaneta T, Nemoto K, et al. The utility of 18F-fluorodeoxyglucose positron emission tomography for early diagnosis of radiation-induced myocardial damage. Int J Radiation Oncol Biol. Phys. 2006;66:845-851.
10. Holly T, Abbott B, Al-Mallah M, et al. ASNC imaging guidelines for nuclear cardiology procedures: single photonemission computed tomography. J Nucl Cardiol. 2010;17:941-973.
11. Neely J, Morgan H. Relationship between carbohydrate metabolism and energy balance of heart muscle. Ann Rev Physiol. 1974;36:36.
12. Pilar H, Gropler R. Imaging of myocardial metabolism. J Nucl Cardiol. 2005;12:345-358.
13. Abel E. Glucose transport in the heart. Front Biosci. 2004;9:201-215.
14. De Groot M, Meeuwis A, Kok P, et al. Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in hear and gut. Eur J Nucl Med Mol Imaging. 2005;32:98-101.
15. Berry J, Baker J, Pieper K, et al. The effect of metabolic milieu on cardiac PET imaging using fluorine-18-deoxyglucose and nitrogen-13 ammonia in normal volunteers. J Nucl Med. 1991;32:1518-1152.
16. Paolisso G, Gambardella A, Galzerano D, et al. Total-body and myocardial substrate oxidation in congestive heart failure. Metabolism. 1994;43:174-179.
17. Taylor M, Wallhaus T, Degrado T, et al. An evaluation of myocardial fatty acid and glucose uptake using PET with (18F) fluoro-6-thia-heptadecanoic acid and (18F) FDG in patients with congestive heart failure. J Nucl Med. 2001;42:55-62.
18. Fukuchi K, Ohta H, Matsumura K, et al. Benign variations and incidental abnormalities of myocardial FDG uptake in the fasting state as encountered during routine oncology positron emission tomography studies. Br J Radiol. 2007;80:3-11.
19. Fujii H, Ide M, Yasuda S, et al. Increased FDG uptake in the wall of the right atrium in people who participated in a cancer screening program with whole-body PET. Ann Nucl Med. 1999;13:55-59.
20. Visser FC. Imaging of cardiac metabolism using radiolabelled glucose, fatty acids and acetate. Coron Artery Dis. 2001;12(suppl 1):S12-S18.
21. Williams G, Kolodny GM. Retrospective study of coronary uptake of 18F-fluorodeoxyglucose in association with calcification and coronary artery disease: a preliminary study. Nuc Medi Comm. 2009;30:287-291.
22. Vilain D, Bochet J, Le Stanc E, et al. Unsuspected hibernating myocardium detected by routine oncology 18F-FDG PET/CT. Eur J Nucl Med Mol Imaging. 2010;37:409.
23. Feygin J, Hu Q, Swingen C, et al. Relationships between regional myocardial wall stress and bioenergetics in hearts with left ventricular hypertrophy. Am J Physiol Heart Circ Physiol. 2008;294:H2313-H2321.