Streptococcus pneumoniae capsular serotype invasiveness correlates with the degree of factor H binding and opsonization with C3b/iC3b

Infection and Immunity

Volumn 81, Issue 1, 2013, Pages 354-363

  Hyams, Catherine ^a   Trzcinski, Krzysztof ^b   Camberlein, Emilie ^a   Weinberger , Daniel M ^c   Chimalapati, Suneeta ^a   Noursadeghi, Mahdad ^d   Lipsitch, Marc ^e   Brown, Jeremy S ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3B; COMPLEMENT FACTOR H;

ANTIGEN BINDING; ARTICLE; BACTERIAL CAPSULE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; CORRELATIONAL STUDY; FLOW CYTOMETRY; HUMAN; MOLECULAR MECHANICS; NEUTROPHIL; NONHUMAN; OPSONIZATION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SEROTYPE; STREPTOCOCCUS PNEUMONIAE;

ADULT; ANTIBODIES, BACTERIAL; BACTERIAL CAPSULES; BACTERIAL PROTEINS; CHILD; COMPLEMENT C3; COMPLEMENT C3B; COMPLEMENT FACTOR H; HUMANS; MUTATION; NEUTROPHILS; PNEUMOCOCCAL INFECTIONS; PROTEIN BINDING; SEROTYPING; STREPTOCOCCUS PNEUMONIAE;

EID: 84871915061     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00862-12     Document Type: Article

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