A similar but distinctive pattern of impaired cortical excitability in first-episode schizophrenia and ADHD

Neuropsychobiology

Volumn 67, Issue 2, 2013, Pages 74-83

  Hasan, Alkomiet ^a,b,d   Schneider, Marc ^c,d   Schneider Axmann, Thomas ^a   Ruge, Diane ^e   Retz, Wolfgang ^c   Rösler, Michael ^c   Falkai, Peter ^b   Wobrock, Thomas ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

^d VINCENT VAN GOGH INSTITUTE FOR PSYCHIATRY   (Netherlands)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Attention deficit hyperactivity disorder; Cortical excitability; Dopamine; First episode schizophrenia; Transcranial magnetic stimulation

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CHLORPROMAZINE; NEUROLEPTIC AGENT;

ADULT; AGE; ARTICLE; ATTENTION DEFICIT DISORDER; COMPARATIVE STUDY; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; EVOKED MUSCLE RESPONSE; FACILITATION; FEMALE; HUMAN; LEFT HEMISPHERE; MAJOR CLINICAL STUDY; MALE; MOTOR CORTEX; NEGATIVE SYNDROME; NERVOUS SYSTEM PARAMETERS; NEUROMUSCULAR FUNCTION; OUTCOME ASSESSMENT; POSITIVE SYNDROME; PRIORITY JOURNAL; RESTING MOTOR THRESHOLD; SCHIZOPHRENIA; TRANSCRANIAL MAGNETIC STIMULATION; BRAIN DEPTH STIMULATION; DISEASE SEVERITY ASSESSMENT; ELECTROMYOGRAPHY; GABAERGIC TRANSMISSION; POSITIVE AND NEGATIVE SYNDROME SCALE; PSYCHOSIS; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS;

ADULT; ANALYSIS OF VARIANCE; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CEREBRAL CORTEX; ELECTROMYOGRAPHY; EVOKED POTENTIALS, MOTOR; FEMALE; FUNCTIONAL LATERALITY; HUMANS; MALE; NEURAL INHIBITION; REACTION TIME; SCHIZOPHRENIA; TRANSCRANIAL MAGNETIC STIMULATION; YOUNG ADULT;

EID: 84871891325     PISSN: 0302282X     EISSN: 14230224     Source Type: Journal    
DOI: 10.1159/000343912     Document Type: Article

References (57)

1. Ross RG, Olincy A, Harris JG, Sullivan B, Radant A: Smooth pursuit eye movements in schizophrenia and attentional dysfunction: adults with schizophrenia, ADHD, and a normal comparison group. Biol Psychiatry 2000; 48: 197-203.
2. Marsh PJ, Williams LM: ADHD and schizophrenia phenomenology: visual scanpaths to emotional faces as a potential psychophysiological marker? Neurosci Biobehav Rev 2006; 30: 651-665.
3. Pani L: Clinical implications of dopamine research in schizophrenia. Curr Med Res Opin 2002; 18(suppl 3):s3-s7.
4. Solanto MV: Dopamine dysfunction in AD/ HD: integrating clinical and basic neuroscience research. Behav Brain Res 2002; 130: 65- 71.
5. Ohno M: The dopaminergic system in attention deficit/hyperactivity disorder. Congenit Anom (Kyoto) 2003; 43: 114-122.
6. Durston S: A review of the biological bases of ADHD: what have we learned from imaging studies? Ment Retard Dev Disabil Res Rev 2003; 9: 184-195.
7. Carriere P, Bonhomme D, Lemperiere T: Amisulpride has a superior benefit/risk profile to haloperidol in schizophrenia: results of a multicentre, double-blind study (the amisulpride study group). Eur Psychiatry 2000; 15: 321-329.
8. Jucaite A, Fernell E, Halldin C, Forssberg H, Farde L: Reduced midbrain dopamine transporter binding in male adolescents with attention- deficit/hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity. Biol Psychiatry 2005; 57: 229-238.
9. Pouget P, Wattiez N, Rivaud-Pechoux S, Gaymard B: A fragile balance: perturbation of GABA mediated circuit in prefrontal cortex generates high intraindividual performance variability. PLoS One 2009; 4:e5208.
10. Hashimoto T, Bazmi HH, Mirnics K, Wu Q, Sampson AR, Lewis DA: Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry 2008; 165: 479-489.
11. Wobrock T, Schneider M, Kadovic D, Schneider-Axmann T, Ecker UK, Retz W, Rosler M, Falkai P: Reduced cortical inhibition in first-episode schizophrenia. Schizophr Res 2008; 105: 252-261.
12. Richter MM, Ehlis AC, Jacob CP, Fallgatter AJ: Cortical excitability in adult patients with attention-deficit/hyperactivity disorder (ADHD). Neurosci Lett 2007; 419: 137- 141.
13. Kujirai T, Caramia MD, Rothwell JC, Day BL, Thompson PD, Ferbert A, Wroe S, Asselman P, Marsden CD: Corticocortical inhibition in human motor cortex. J Physiol 1993; 471: 501-519.
14. Ziemann U: TMS and drugs. Clin Neurophysiol 2004; 115: 1717-1729.
15. Werhahn KJ, Kunesch E, Noachtar S, Benecke R, Classen J: Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans. J Physiol 1999; 517(Pt 2):591-597.
16. Siebner HR, Dressnandt J, Auer C, Conrad B: Continuous intrathecal baclofen infusions induced a marked increase of the transcranially evoked silent period in a patient with generalized dystonia. Muscle Nerve 1998; 21: 1209-1212.
17. Pascual-Leone A, Manoach DS, Birnbaum R, Goff DC: Motor cortical excitability in schizophrenia. Biol Psychiatry 2002; 52: 24- 31.
18. Eichhammer P, Wiegand R, Kharraz A, Langguth B, Binder H, Hajak G: Cortical excitability in neuroleptic-naive first-episode schizophrenic patients. Schizophr Res 2004; 67: 253-259.
19. Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S: Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation. Arch Gen Psychiatry 2002; 59: 347-354.
20. Fitzgerald PB, Brown TL, Daskalakis ZJ, Kulkarni J: A transcranial magnetic stimulation study of inhibitory deficits in the motor cortex in patients with schizophrenia. Psychiatry Res 2002; 114: 11-22.
21. Wobrock T, Schneider-Axmann T, Retz W, Rosler M, Kadovic D, Falkai P, Schneider M: Motor circuit abnormalities in first-episode schizophrenia assessed with transcranial magnetic stimulation. Pharmacopsychiatry 2009; 42: 194-201.
22. Moll GH, Heinrich H, Trott G, Wirth S, Rothenberger A: Deficient intracortical inhibition in drug-naive children with attention- deficit hyperactivity disorder is enhanced by methylphenidate. Neurosci Lett 2000; 284: 121-125.
23. Buchmann J, Gierow W, Weber S, Hoeppner J, Klauer T, Benecke R, Haessler F, Wolters A: Restoration of disturbed intracortical motor inhibition and facilitation in attention deficit hyperactivity disorder children by methylphenidate. Biol Psychiatry 2007; 62: 963- 969.
24. Gilbert DL, Bansal AS, Sethuraman G, Sallee FR, Zhang J, Lipps T, Wassermann EM: Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndrome. Mov Disord 2004; 19: 416-425.
25. Schneider M, Retz W, Freitag C, Irsch J, Graf P, Retz-Junginger P, Rosler M: Impaired cortical inhibition in adult ADHD patients: a study with transcranial magnetic stimulation. J Neural Transm Suppl 2007: 303-309.
26. Hoeppner J, Neumeyer M, Wandschneider R, Herpertz SC, Gierow W, Haessler F, Buchmann J: Intracortical motor inhibition and facilitation in adults with attention deficit/ hyperactivity disorder. J Neural Transm 2008; 115: 1701-1707.
27. Hoeppner J, Wandschneider R, Neumeyer M, Gierow W, Haessler F, Herpertz SC, Buchmann J: Impaired transcallosally mediated motor inhibition in adults with attentiondeficit/ hyperactivity disorder is modulated by methylphenidate. J Neural Transm 2008; 115: 777-785.
28. Annett M: A classification of hand preference by association analysis. Br J Psychol 1970; 61: 303-321.
29. Wittchen HU, Wunderlich U, Gruschwitz S, Zaudig M: Strukturiertes klinisches Interview für DSM-IV; in Spitzer RL, Williams JB, Gibbon M, First MB (eds): Achse I: Psychische Störungen. A German, Advanced Adaptation of the Original SCID Version. Göttingen, Hogrefe, 1997.
30. National Institute of Mental Health: CGI: Clinical Global Impressions; in Guy W, Bonato RR (eds): Manual for the ECDEU Assessment Battery. Chevy Chase, National Institute of Mental Health, 1976
31. Endicott J, Spitzer RL, Fleiss JL, Cohen J: The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 1976; 33: 766-771.
32. Kay SR, Fiszbein A, Opler LA: The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13: 261- 276.
33. Woods SW: Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry 2003; 64: 663-667.
34. Rösler M, Retz W, Retz-Junginger P, Thome J, Supprian T, Nissen T, Stieglitz RD, Blocher D, Hengesch G, Trott GE: Tools for the diagnosis of attention-deficit/hyperactivity disorder in adults. Self-rating behaviour questionnaire and diagnostic checklist. Nervenarzt 2004; 75: 888-895.
35. Wender PH, Wolf LE, Wasserstein J: Adults with ADHD. An overview. Ann NY Acad Sci 2001; 931: 1-16.
36. Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S: Effect of antipsychotics on cortical inhibition using transcranial magnetic stimulation. Psychopharmacology (Berl) 2003; 170: 255-262.
37. Liu SK, Fitzgerald PB, Daigle M, Chen R, Daskalakis ZJ: The relationship between cortical inhibition, antipsychotic treatment, and the symptoms of schizophrenia. Biol Psychiatry 2009; 65: 503-509.
38. Hasan A, Nitsche MA, Rein B, Schneider- Axmann T, Guse B, Gruber O, Falkai P, Wobrock T: Dysfunctional long-term potentiation- like plasticity in schizophrenia revealed by transcranial direct current stimulation. Behav Brain Res 2011; 224: 15-22.
39. Bajbouj M, Gallinat J, Niehaus L, Lang UE, Roricht S, Meyer BU: Abnormalities of inhibitory neuronal mechanisms in the motor cortex of patients with schizophrenia. Pharmacopsychiatry 2004; 37: 74-80.
40. Hasan A, Nitsche MA, Herrmann M, Schneider-Axmann T, Marshall L, Gruber O, Falkai P, Wobrock T: Impaired long-term depression in schizophrenia: a cathodal tDCS pilot study. Brain Stimul 2012; 5: 475- 483.
41. McDonnell MN, Orekhov Y, Ziemann U: The role of GABA(b) receptors in intracortical inhibition in the human motor cortex. Exp Brain Res 2006; 173: 86-93.
42. Ni Z, Gunraj C, Chen R: Short interval intracortical inhibition and facilitation during the silent period in human. J Physiol 2007; 583: 971-982.
43. Hale TS, Smalley SL, Walshaw PD, Hanada G, Macion J, McCracken JT, McGough JJ, Loo SK: Atypical EEG beta asymmetry in adults with ADHD. Neuropsychologia 2010; 48: 3532-3539.
44. White T, Nelson M, Lim KO: Diffusion tensor imaging in psychiatric disorders. Top Magn Reson Imaging 2008; 19: 97-109.
45. Shapleske J, Rossell SL, Woodruff PW, David AS: The planum temporale: a systematic, quantitative review of its structural, functional and clinical significance. Brain Res Brain Res Rev 1999; 29: 26-49.
46. Schmitt A, Hasan A, Gruber O, Falkai P: Schizophrenia as a disorder of disconnectivity. Eur Arch Psychiatry Clin Neurosci 2011; 261(Suppl 2):S150-S154.
47. Fitzgerald PB, Brown TL, Daskalakis ZJ: The application of transcranial magnetic stimulation in psychiatry and neurosciences research. Acta Psychiatr Scand 2002; 105: 324- 340.
48. Suppa A, Ortu E, Zafar N, Deriu F, Paulus W, Berardelli A, Rothwell JC: Theta burst stimulation induces after-effects on contralateral primary motor cortex excitability in humans. J Physiol 2008; 586: 4489-4500.
49. Wassermann EM, Wedegaertner FR, Ziemann U, George MS, Chen R: Crossed reduction of human motor cortex excitability by 1-Hz transcranial magnetic stimulation. Neurosci Lett 1998; 250: 141-144.
50. Heide G, Witte OW, Ziemann U: Physiology of modulation of motor cortex excitability by low-frequency suprathreshold repetitive transcranial magnetic stimulation. Exp Brain Res 2006; 171: 26-34.
51. Cantello R, Tarletti R, Civardi C: Transcranial magnetic stimulation and Parkinson's disease. Brain Res Brain Res Rev 2002; 38: 309-327.
52. Beauregard M, Ferron A: Dopamine modulates the inhibition induced by GABA in rat cerebral cortex: an iontophoretic study. Eur J Pharmacol 1991; 205: 225-231.
53. Schneider M, Retz W, Rösler M: Effects of long-acting methylphenidate in adults with attention deficit hyperactivity disorder: a study with paired-pulse transcranial magnetic stimulation. Neuropsychobiology 2011; 64: 195-201.
54. Moll GH, Heinrich H, Trott GE, Wirth S, Bock N, Rothenberger A: Children with comorbid attention-deficit-hyperactivity disorder and tic disorder: evidence for additive inhibitory deficits within the motor system. Ann Neurol 2001; 49: 393-396.
55. Nitsche MA, Monte-Silva K, Kuo MF, Paulus W: Dopaminergic impact on cortical excitability in humans. Rev Neurosci 2010; 21: 289-298.
56. Bajbouj M, Lisanby SH, Lang UE, Danker- Hopfe H, Heuser I, Neu P: Evidence for impaired cortical inhibition in patients with unipolar major depression. Biol Psychiatry 2006; 59: 395-400.
57. Greenberg BD, Ziemann U, Cora-Locatelli G, Harmon A, Murphy DL, Keel JC, Wassermann EM: Altered cortical excitability in obsessive-compulsive disorder. Neurology 2000; 54: 142-147.