-
1
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley M.A., et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 2001, 411(6836):480-484.
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 480-484
-
-
Cowley, M.A.1
-
2
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz M.W., et al. Identification of targets of leptin action in rat hypothalamus. The Journal of Clinical Investigation 1996, 98(5):1101-1106.
-
(1996)
The Journal of Clinical Investigation
, vol.98
, Issue.5
, pp. 1101-1106
-
-
Schwartz, M.W.1
-
3
-
-
0030775971
-
Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus
-
Schwartz M.W., et al. Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes 1997, 46(12):2119-2123.
-
(1997)
Diabetes
, vol.46
, Issue.12
, pp. 2119-2123
-
-
Schwartz, M.W.1
-
4
-
-
0032436307
-
Leptin activates hypothalamic CART neurons projecting to the spinal cord
-
Elias C.F., et al. Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron 1998, 21(6):1375-1385.
-
(1998)
Neuron
, vol.21
, Issue.6
, pp. 1375-1385
-
-
Elias, C.F.1
-
5
-
-
0029098589
-
The role of neuropeptide Y in the antiobesity action of the obese gene product
-
Stephens T.W., et al. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 1995, 377(6549):530-532.
-
(1995)
Nature
, vol.377
, Issue.6549
, pp. 530-532
-
-
Stephens, T.W.1
-
6
-
-
33748541108
-
Leptin regulation of the mesoaccumbens dopamine pathway
-
Fulton S., et al. Leptin regulation of the mesoaccumbens dopamine pathway. Neuron 2006, 51(6):811-822.
-
(2006)
Neuron
, vol.51
, Issue.6
, pp. 811-822
-
-
Fulton, S.1
-
7
-
-
33748540764
-
Leptin receptor signaling in midbrain dopamine neurons regulates feeding
-
Hommel J.D., et al. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron 2006, 51(6):801-810.
-
(2006)
Neuron
, vol.51
, Issue.6
, pp. 801-810
-
-
Hommel, J.D.1
-
8
-
-
0028845877
-
Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M., et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Medicine 1995, 1(11):1155-1161.
-
(1995)
Nature Medicine
, vol.1
, Issue.11
, pp. 1155-1161
-
-
Maffei, M.1
-
9
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y., et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372(6505):425-432.
-
(1994)
Nature
, vol.372
, Issue.6505
, pp. 425-432
-
-
Zhang, Y.1
-
10
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas J.L., et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science (New York, NY) 1995, 269(5223):543-546.
-
(1995)
Science (New York, NY)
, vol.269
, Issue.5223
, pp. 543-546
-
-
Halaas, J.L.1
-
11
-
-
0037458468
-
Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
-
Figlewicz D.P., et al. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Research 2003, 964(1):107-115.
-
(2003)
Brain Research
, vol.964
, Issue.1
, pp. 107-115
-
-
Figlewicz, D.P.1
-
12
-
-
34548675339
-
Leptin regulates striatal regions and human eating behavior
-
Farooqi I.S., et al. Leptin regulates striatal regions and human eating behavior. Science (New York, NY) 2007, 317(5843):1355.
-
(2007)
Science (New York, NY)
, vol.317
, Issue.5843
, pp. 1355
-
-
Farooqi, I.S.1
-
13
-
-
6844250767
-
Dopamine receptors: from structure to function
-
Missale C., et al. Dopamine receptors: from structure to function. Physiological Reviews 1998, 78(1):189-225.
-
(1998)
Physiological Reviews
, vol.78
, Issue.1
, pp. 189-225
-
-
Missale, C.1
-
14
-
-
0030838736
-
Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice
-
Kelly M.A., et al. Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron 1997, 19(1):103-113.
-
(1997)
Neuron
, vol.19
, Issue.1
, pp. 103-113
-
-
Kelly, M.A.1
-
15
-
-
78649903233
-
New insights into the endocrine and metabolic roles of dopamine D2 receptors gained from the Drd2 mouse
-
Garcia-Tornadu I., et al. New insights into the endocrine and metabolic roles of dopamine D2 receptors gained from the Drd2 mouse. Neuroendocrinology 2010, 92(4):207-214.
-
(2010)
Neuroendocrinology
, vol.92
, Issue.4
, pp. 207-214
-
-
Garcia-Tornadu, I.1
-
16
-
-
18844378345
-
Blockade of melanocortin transmission inhibits cocaine reward
-
Hsu R., et al. Blockade of melanocortin transmission inhibits cocaine reward. The European Journal of Neuroscience 2005, 21(8):2233-2242.
-
(2005)
The European Journal of Neuroscience
, vol.21
, Issue.8
, pp. 2233-2242
-
-
Hsu, R.1
-
18
-
-
40849083517
-
Food reward in the absence of taste receptor signaling
-
de Araujo I.E., et al. Food reward in the absence of taste receptor signaling. Neuron 2008, 57(6):930-941.
-
(2008)
Neuron
, vol.57
, Issue.6
, pp. 930-941
-
-
de Araujo, I.E.1
-
19
-
-
33748560432
-
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite
-
Abizaid A., et al. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. The Journal of Clinical Investigation 2006, 116(12):3229-3239.
-
(2006)
The Journal of Clinical Investigation
, vol.116
, Issue.12
, pp. 3229-3239
-
-
Abizaid, A.1
-
20
-
-
33748423509
-
Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis
-
Pardini A.W., et al. Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis. Brain Research 2006, 1112(1):169-178.
-
(2006)
Brain Research
, vol.1112
, Issue.1
, pp. 169-178
-
-
Pardini, A.W.1
-
21
-
-
66149141484
-
Leptin targets in the mouse brain
-
Scott M.M., et al. Leptin targets in the mouse brain. The Journal of Comparative Neurology 2009, 514(5):518-532.
-
(2009)
The Journal of Comparative Neurology
, vol.514
, Issue.5
, pp. 518-532
-
-
Scott, M.M.1
-
22
-
-
0030762351
-
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
-
Guan X.M., et al. Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Research Molecular Brain Research 1997, 48(1):23-29.
-
(1997)
Brain Research Molecular Brain Research
, vol.48
, Issue.1
, pp. 23-29
-
-
Guan, X.M.1
-
23
-
-
42649116436
-
Ghrelin modulates brain activity in areas that control appetitive behavior
-
Malik S., et al. Ghrelin modulates brain activity in areas that control appetitive behavior. Cell Metabolism 2008, 7(5):400-409.
-
(2008)
Cell Metabolism
, vol.7
, Issue.5
, pp. 400-409
-
-
Malik, S.1
-
24
-
-
36749097922
-
Leptin replacement alters brain response to food cues in genetically leptin-deficient adults
-
Baicy K., et al. Leptin replacement alters brain response to food cues in genetically leptin-deficient adults. Proceedings of the National Academy of Sciences of the United States of America 2007, 104(46):18276-18279.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.46
, pp. 18276-18279
-
-
Baicy, K.1
-
25
-
-
79952572475
-
Leptin regulates energy balance and motivation through action at distinct neural circuits
-
Davis J.F., et al. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biological Psychiatry 2011, 69(7):668-674.
-
(2011)
Biological Psychiatry
, vol.69
, Issue.7
, pp. 668-674
-
-
Davis, J.F.1
-
26
-
-
0037057802
-
The need to feed: homeostatic and hedonic control of eating
-
Saper C.B., Chou T.C., Elmquist J.K. The need to feed: homeostatic and hedonic control of eating. Neuron 2002, 36(2):199-211.
-
(2002)
Neuron
, vol.36
, Issue.2
, pp. 199-211
-
-
Saper, C.B.1
Chou, T.C.2
Elmquist, J.K.3
-
27
-
-
17844401704
-
Anatomy and regulation of the central melanocortin system
-
Cone R.D. Anatomy and regulation of the central melanocortin system. Nature Neuroscience 2005, 8(5):571-578.
-
(2005)
Nature Neuroscience
, vol.8
, Issue.5
, pp. 571-578
-
-
Cone, R.D.1
-
28
-
-
0032900284
-
Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides
-
Marsh D.J., et al. Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nature Genetics 1999, 21(1):119-122.
-
(1999)
Nature Genetics
, vol.21
, Issue.1
, pp. 119-122
-
-
Marsh, D.J.1
-
29
-
-
41549111593
-
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion
-
van de Wall E., et al. Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology 2008, 149(4):1773-1785.
-
(2008)
Endocrinology
, vol.149
, Issue.4
, pp. 1773-1785
-
-
van de Wall, E.1
-
30
-
-
84863267488
-
Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice
-
Berglund E.D., et al. Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice. The Journal of Clinical Investigation 2012, 122(3):1000-1009.
-
(2012)
The Journal of Clinical Investigation
, vol.122
, Issue.3
, pp. 1000-1009
-
-
Berglund, E.D.1
-
31
-
-
0242499401
-
Reduced dopaminergic tone in hypothalamic neural circuits: expression of a thrifty genotype underlying the metabolic syndrome?
-
Pijl H. Reduced dopaminergic tone in hypothalamic neural circuits: expression of a thrifty genotype underlying the metabolic syndrome?. European Journal of Pharmacology 2003, 480(1-3):125-131.
-
(2003)
European Journal of Pharmacology
, vol.480
, Issue.1-3
, pp. 125-131
-
-
Pijl, H.1
-
32
-
-
77953865230
-
Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice
-
Pfaffly J., et al. Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice. Synapse (New York, NY) 2010, 64(7):503-510.
-
(2010)
Synapse (New York, NY)
, vol.64
, Issue.7
, pp. 503-510
-
-
Pfaffly, J.1
-
33
-
-
77950574396
-
Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors
-
Kim K.S., et al. Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. The Journal of Biological Chemistry 2010, 285(12):8905-8917.
-
(2010)
The Journal of Biological Chemistry
, vol.285
, Issue.12
, pp. 8905-8917
-
-
Kim, K.S.1
-
34
-
-
77449101244
-
A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
-
Butler A.A., Kozak L.P. A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes 2010, 59(2):323-329.
-
(2010)
Diabetes
, vol.59
, Issue.2
, pp. 323-329
-
-
Butler, A.A.1
Kozak, L.P.2
-
35
-
-
0025921566
-
Effects of dopamine D1 and dopamine D2 antagonists on the free feeding and drinking patterns of rats
-
Clifton P.G., Rusk I.N., Cooper S.J. Effects of dopamine D1 and dopamine D2 antagonists on the free feeding and drinking patterns of rats. Behavioral Neuroscience 1991, 105(2):272-281.
-
(1991)
Behavioral Neuroscience
, vol.105
, Issue.2
, pp. 272-281
-
-
Clifton, P.G.1
Rusk, I.N.2
Cooper, S.J.3
-
36
-
-
0028043808
-
Parametric studies of selective D1 or D2 antagonists: effects on appetitive and feeding behaviour
-
Rusk I.N., Cooper S.J. Parametric studies of selective D1 or D2 antagonists: effects on appetitive and feeding behaviour. Behavioural Pharmacology 1994, 5(6):615-622.
-
(1994)
Behavioural Pharmacology
, vol.5
, Issue.6
, pp. 615-622
-
-
Rusk, I.N.1
Cooper, S.J.2
-
37
-
-
2542475178
-
Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein
-
Chen H.Y., et al. Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology 2004, 145(6):2607-2612.
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2607-2612
-
-
Chen, H.Y.1
-
38
-
-
33846975815
-
Metabolic considerations in the use of antipsychotic medications: a review of recent evidence
-
Newcomer J.W. Metabolic considerations in the use of antipsychotic medications: a review of recent evidence. The Journal of Clinical Psychiatry 2007, 68(Suppl 1):20-27.
-
(2007)
The Journal of Clinical Psychiatry
, vol.68
, Issue.SUPPL 1
, pp. 20-27
-
-
Newcomer, J.W.1
-
39
-
-
4344622156
-
Pharmacogenetics of antipsychotic-induced weight gain
-
Correll C.U., Malhotra A.K. Pharmacogenetics of antipsychotic-induced weight gain. Psychopharmacology (Berl) 2004, 174(4):477-489.
-
(2004)
Psychopharmacology (Berl)
, vol.174
, Issue.4
, pp. 477-489
-
-
Correll, C.U.1
Malhotra, A.K.2
-
41
-
-
33751169810
-
Activation of dopamine D2 receptors simultaneously ameliorates various metabolic features of obese women
-
Kok P., et al. Activation of dopamine D2 receptors simultaneously ameliorates various metabolic features of obese women. American Journal of Physiology, Endocrinology and metabolism 2006, 291(5):E1038-E1043.
-
(2006)
American Journal of Physiology, Endocrinology and metabolism
, vol.291
, Issue.5
-
-
Kok, P.1
-
42
-
-
33747744740
-
Activation of dopamine D2 receptors lowers circadian leptin concentrations in obese women
-
Kok P., et al. Activation of dopamine D2 receptors lowers circadian leptin concentrations in obese women. The Journal of Clinical Endocrinology and Metabolism 2006, 91(8):3236-3240.
-
(2006)
The Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.8
, pp. 3236-3240
-
-
Kok, P.1
-
43
-
-
0030807442
-
Bilateral hypothalamic dopamine infusion in male Zucker rat suppresses feeding due to reduced meal size
-
Yang Z.J., et al. Bilateral hypothalamic dopamine infusion in male Zucker rat suppresses feeding due to reduced meal size. Pharmacology, Biochemistry and Behavior 1997, 58(3):631-635.
-
(1997)
Pharmacology, Biochemistry and Behavior
, vol.58
, Issue.3
, pp. 631-635
-
-
Yang, Z.J.1
-
44
-
-
67849092898
-
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding
-
Leinninger G.M., et al. Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metabolism 2009, 10(2):89-98.
-
(2009)
Cell Metabolism
, vol.10
, Issue.2
, pp. 89-98
-
-
Leinninger, G.M.1
-
45
-
-
77957754156
-
Neuropharmacology of learned flavor preferences
-
Touzani K., Bodnar R.J., Sclafani A. Neuropharmacology of learned flavor preferences. Pharmacology, Biochemistry, and Behavior 2010, 97(1):55-62.
-
(2010)
Pharmacology, Biochemistry, and Behavior
, vol.97
, Issue.1
, pp. 55-62
-
-
Touzani, K.1
Bodnar, R.J.2
Sclafani, A.3
-
46
-
-
62749183678
-
Sugar and fat bingeing have notable differences in addictive-like behavior
-
Avena N.M., Rada P., Hoebel B.G. Sugar and fat bingeing have notable differences in addictive-like behavior. The Journal of Nutrition 2009, 139(3):623-628.
-
(2009)
The Journal of Nutrition
, vol.139
, Issue.3
, pp. 623-628
-
-
Avena, N.M.1
Rada, P.2
Hoebel, B.G.3
-
47
-
-
0032423613
-
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
-
Berridge K.C., Robinson T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?. Brain Research Brain Research Reviews 1998, 28(3):309-369.
-
(1998)
Brain Research Brain Research Reviews
, vol.28
, Issue.3
, pp. 309-369
-
-
Berridge, K.C.1
Robinson, T.E.2
-
48
-
-
58149503649
-
Insulin, leptin, and food reward: update 2008
-
Figlewicz D.P., Benoit S.C. Insulin, leptin, and food reward: update 2008. American Journal of Physiology Regulatory, Integrative and Comparative Physiology 2009, 296(1):R9-R19.
-
(2009)
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
, vol.296
, Issue.1
-
-
Figlewicz, D.P.1
Benoit, S.C.2
-
49
-
-
36348992560
-
Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo muPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography
-
Thanos P.K., et al. Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo muPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography. Synapse (New York, NY) 2008, 62(1):50-61.
-
(2008)
Synapse (New York, NY)
, vol.62
, Issue.1
, pp. 50-61
-
-
Thanos, P.K.1
-
50
-
-
0035798931
-
Brain dopamine and obesity
-
Wang G.J., et al. Brain dopamine and obesity. Lancet 2001, 357(9253):354-357.
-
(2001)
Lancet
, vol.357
, Issue.9253
, pp. 354-357
-
-
Wang, G.J.1
-
51
-
-
54249084372
-
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors
-
Volkow N.D., et al. Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors. Neuroimage 2008, 42(4):1537-1543.
-
(2008)
Neuroimage
, vol.42
, Issue.4
, pp. 1537-1543
-
-
Volkow, N.D.1
-
52
-
-
77957274035
-
Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons
-
Briggs D.I., et al. Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons. Endocrinology 2010, 151(10):4745-4755.
-
(2010)
Endocrinology
, vol.151
, Issue.10
, pp. 4745-4755
-
-
Briggs, D.I.1
-
53
-
-
33847319765
-
Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons
-
Enriori P.J., et al. Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. Cell Metabolism 2007, 5(3):181-194.
-
(2007)
Cell Metabolism
, vol.5
, Issue.3
, pp. 181-194
-
-
Enriori, P.J.1
-
54
-
-
80052156758
-
Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance
-
Enriori P.J., et al. Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2011, 31(34):12189-12197.
-
(2011)
The Journal of Neuroscience: The Official Journal of the Society for Neuroscience
, vol.31
, Issue.34
, pp. 12189-12197
-
-
Enriori, P.J.1
-
55
-
-
34547828083
-
Interactions between the cognitive and metabolic brain in the control of food intake
-
Berthoud H.R. Interactions between the cognitive and metabolic brain in the control of food intake. Physiology and Behavior 2007, 91(5):486-498.
-
(2007)
Physiology and Behavior
, vol.91
, Issue.5
, pp. 486-498
-
-
Berthoud, H.R.1
|