The superhealing MRL background improves muscular dystrophy

Skeletal Muscle

Volumn 2, Issue 1, 2012, Pages

  Heydemann, Ahlke ^a,c   Swaggart, Kayleigh A ^b   Kim, Gene H ^a   Holley Cuthrell, Jenan ^a   Hadhazy, Michele ^a   McNally, Elizabeth M ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Cardiomyopathy; Fibrosis; MRL; Muscular dystrophy

Indexed keywords

MUS;

EID: 84871864711     PISSN: None     EISSN: 20445040     Source Type: Journal    
DOI: 10.1186/2044-5040-2-26     Document Type: Article

References (41)

1. Clark LD, Clark RK, Heber-Katz E. A new murine model for mammalian wound repair and regeneration. Clin Immunol Immunopathol 1998, 88:35-45. 10.1006/clin.1998.4519, 9683548.
2. McBrearty BA, Clark LD, Zhang XM, Blankenhorn EP, Heber-Katz E. Genetic analysis of a mammalian wound-healing trait. Proc Natl Acad Sci U S A 1998, 95:11792-11797. 10.1073/pnas.95.20.11792, 21719, 9751744.
3. Gourevitch DL, Clark L, Bedelbaeva K, Leferovich J, Heber-Katz E. Dynamic changes after murine digit amputation: the MRL mouse digit shows waves of tissue remodeling, growth, and apoptosis. Wound Repair Regen 2009, 17:447-455. 10.1111/j.1524-475X.2009.00492.x, 19660054.
4. Ueno M, Lyons BL, Burzenski LM, Gott B, Shaffer DJ, Roopenian DC, Shultz LD. Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature. Invest Ophthalmol Vis Sci 2005, 46:4097-4106. 10.1167/iovs.05-0548, 16249486.
5. Leferovich JM, Bedelbaeva K, Samulewicz S, Zhang XM, Zwas D, Lankford EB, Heber-Katz E. Heart regeneration in adult MRL mice. Proc Natl Acad Sci U S A 2001, 98:9830-9835. 10.1073/pnas.181329398, 55538, 11493713.
6. Naseem RH, Meeson AP, Michael Dimaio J, White MD, Kallhoff J, Humphries C, Goetsch SC, De Windt LJ, Williams MA, Garry MG, Garry DJ. Reparative myocardial mechanisms in adult C57BL/6 and MRL mice following injury. Physiol Genomics 2007, 30:44-52. 10.1152/physiolgenomics.00070.2006, 17327495.
7. Abdullah I, Lepore JJ, Epstein JA, Parmacek MS, Gruber PJ. MRL mice fail to heal the heart in response to ischemia-reperfusion injury. Wound Repair Regen 2005, 13:205-208. 10.1111/j.1067-1927.2005.130212.x, 15828946.
8. Cimini M, Fazel S, Fujii H, Zhou S, Tang G, Weisel RD, Li RK. The MRL mouse heart does not recover ventricular function after a myocardial infarction. Cardiovasc Pathol 2008, 17:32-39. 10.1016/j.carpath.2007.06.006, 18160058.
9. Grisel P, Meinhardt A, Lehr HA, Kappenberger L, Barrandon Y, Vassalli G. The MRL mouse repairs both cryogenic and ischemic myocardial infarcts with scar. Cardiovasc Pathol 2008, 17:14-22. 10.1016/j.carpath.2007.01.007, 18160056.
10. Robey TE, Murry CE. Absence of regeneration in the MRL/MpJ mouse heart following infarction or cryoinjury. Cardiovasc Pathol 2008, 17:6-13. 10.1016/j.carpath.2007.01.005, 2766607, 18160055.
11. Oh YS, Thomson LE, Fishbein MC, Berman DS, Sharifi B, Chen PS. Scar formation after ischemic myocardial injury in MRL mice. Cardiovasc Pathol 2004, 13:203-206. 10.1016/j.carpath.2004.03.610, 15210135.
12. Harty M, Neff AW, King MW, Mescher AL. Regeneration or scarring: an immunologic perspective. Dev Dyn 2003, 226:268-279. 10.1002/dvdy.10239, 12557205.
13. Gourevitch D, Clark L, Chen P, Seitz A, Samulewicz SJ, Heber-Katz E. Matrix metalloproteinase activity correlates with blastema formation in the regenerating MRL mouse ear hole model. Dev Dyn 2003, 226:377-387. 10.1002/dvdy.10243, 12557216.
14. Heber-Katz E, Leferovich J, Bedelbaeva K, Gourevitch D, Clark L. The scarless heart and the MRL mouse. Philos Trans R Soc Lond B Biol Sci 2004, 359:785-793. 10.1098/rstb.2004.1468, 1693365, 15293806.
15. Bedelbaeva K, Gourevitch D, Clark L, Chen P, Leferovich JM, Heber-Katz E. The MRL mouse heart healing response shows donor dominance in allogeneic fetal liver chimeric mice. Cloning Stem Cells 2004, 6:352-363. 10.1089/clo.2004.6.352, 15671663.
16. Heydemann A. The super super-healing MRL mouse strain. Front Biol 2012, in press.
17. Spencer MJ, Montecino-Rodriguez E, Dorshkind K, Tidball JG. Helper (CD4(+)) and cytotoxic (CD8(+)) T cells promote the pathology of dystrophin-deficient muscle. Clin Immunol 2001, 98:235-243. 10.1006/clim.2000.4966, 11161980.
18. Hack AA, Ly CT, Jiang F, Clendenin CJ, Sigrist KS, Wollmann RL, McNally EM. Gamma-sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin. J Cell Biol 1998, 142:1279-1287. 10.1083/jcb.142.5.1279, 2149352, 9732288.
19. Heydemann A, Huber JM, Demonbreun A, Hadhazy M, McNally EM. Genetic background influences muscular dystrophy. Neuromuscul Disord 2005, 15:601-609. 10.1016/j.nmd.2005.05.004, 16084087.
20. Straub V, Rafael JA, Chamberlain JS, Campbell KP. Animal models for muscular dystrophy show different patterns of sarcolemmal disruption. J Cell Biol 1997, 139:375-385. 10.1083/jcb.139.2.375, 2139791, 9334342.
21. Heydemann A, Ceco E, Lim JE, Hadhazy M, Ryder P, Moran JL, Beier DR, Palmer AA, McNally EM. Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest 2009, 119:3703-3712. 10.1172/JCI39845, 2786802, 19884661.
22. Matsuda R, Nishikawa A, Tanaka H. Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: evidence of apoptosis in dystrophin-deficient muscle. J Biochem (Tokyo) 1995, 118:959-964.
23. Thurston G, Suri C, Smith K, McClain J, Sato TN, Yancopoulos GD, McDonald DM. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 1999, 286:2511-2514. 10.1126/science.286.5449.2511, 10617467.
24. Flesch M, Schiffer F, Zolk O, Pinto Y, Rosenkranz S, Hirth-Dietrich C, Arnold G, Paul M, Bohm M. Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy. Hypertension 1997, 30:383-391. 10.1161/01.HYP.30.3.383, 9314421.
25. Collins KA, Korcarz CE, Shroff SG, Bednarz JE, Fentzke RC, Lin H, Leiden JM, Lang RM. Accuracy of echocardiographic estimates of left ventricular mass in mice. Am J Physiol Heart Circ Physiol 2001, 280:H1954-H1962.
26. Wheeler MT, Korcarz CE, Collins KA, Lapidos KA, Hack AA, Lyons MR, Zarnegar S, Earley JU, Lang RM, McNally EM. Secondary coronary artery vasospasm promotes cardiomyopathy progression. Am J Pathol 2004, 164:1063-1071. 10.1016/S0002-9440(10)63193-8, 1614719, 14982859.
27. Moran JL, Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Bjork BC, Li C, Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ, Kucherlapati R, Beier DR. Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. Genome Res 2006, 16:436-440. 10.1101/gr.4563306, 1415208, 16461637.
28. Collaborative Cross Consortium The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics 2012, 190:389-401. 3276630, 22345608, Collaborative Cross Consortium.
29. Cheng R, Abney M, Palmer AA, Skol AD. QTLRel: an R package for genome-wide association studies in which relatedness is a concern. BMC Genet 2011, 12:66. 3160955, 21794153.
30. Cheng R, Lim JE, Samocha KE, Sokoloff G, Abney M, Skol AD, Palmer AA. Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations. Genetics 2010, 185:1033-1044. 10.1534/genetics.110.116863, 2907190, 20439773.
31. McNally EM, Passos-Bueno MR, Bonnemann CG, Vainzof M, de Sa Moreira E, Lidov HG, Othmane KB, Denton PH, Vance JM, Zatz M, Kunkel LM. Mild and severe muscular dystrophy caused by a single gamma-sarcoglycan mutation. Am J Hum Genet 1996, 59:1040-1047. 1914841, 8900232.
32. Stedman HH, Sweeney HL, Shrager JB, Maguire HC, Panettieri RA, Petrof B, Narusawa M, Leferovich JM, Sladky JT, Kelly AM. The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature 1991, 352:536-539. 10.1038/352536a0, 1865908.
33. Swaggart KA, Heydemann A, Palmer AA, McNally EM. Distinct genetic regions modify specific muscle groups in muscular dystrophy. Physiol Genomics 2011, 43:24-31. 10.1152/physiolgenomics.00172.2010, 3026347, 20959497.
34. Bedelbaeva K, Snyder A, Gourevitch D, Clark L, Zhang XM, Leferovich J, Cheverud JM, Lieberman P, Heber-Katz E. Lack of p21 expression links cell cycle control and appendage regeneration in mice. Proc Natl Acad Sci U S A 2010, 107:5845-5850. 10.1073/pnas.1000830107, 2851923, 20231440.
35. Bernasconi P, Torchiana E, Confalonieri P, Brugnoni R, Barresi R, Mora M, Cornelio F, Morandi L, Mantegazza R. Expression of transforming growth factor-beta 1 in dystrophic patient muscles correlates with fibrosis. Pathogenetic role of a fibrogenic cytokine. J Clin Invest 1995, 96:1137-1144. 10.1172/JCI118101, 185304, 7635950.
36. Cohn RD, Van Erp C, Habashi JP, Soleimani AA, Klein EC, Lisi MT, Gamradt M, ap Rhys CM, Holm TM, Loeys BL, Ramirez F, Judge DP, Ward CW, Dietz HC. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. Nat Med 2007, 13:204-210. 10.1038/nm1536, 3138130, 17237794.
37. Kench JA, Russell DM, Fadok VA, Young SK, Worthen GS, Jones-Carson J, Henson JE, Henson PM, Nemazee D. Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse. Clin Immunol 1999, 92:300-310. 10.1006/clim.1999.4754, 10479535.
38. Kitamoto T, Hanaoka K. Notch3 null mutation in mice causes muscle hyperplasia by repetitive muscle regeneration. Stem Cells 2010, 28:2205-2216. 10.1002/stem.547, 20960513.
39. Parker MH, Loretz C, Tyler AE, Duddy WJ, Hall JK, Olwin BB, Bernstein ID, Storb R, Tapscott SJ. Activation of notch signaling during ex vivo expansion maintains donor muscle cell engraftment. Stem Cells 2012, 30:2212-20. 10.1002/stem.1181, 22865615.
40. Ruschke K, Hiepen C, Becker J, Knaus P. BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system. Cell Tissue Res 2012, 347:521-544. 10.1007/s00441-011-1283-6, 22327483.
41. Naviaux RK, Le TP, Bedelbaeva K, Leferovich J, Gourevitch D, Sachadyn P, Zhang XM, Clark L, Heber-Katz E. Retained features of embryonic metabolism in the adult MRL mouse. Mol Genet Metab 2009, 96:133-144. 10.1016/j.ymgme.2008.11.164, 19131261.