Clinical Protection of Goats against CpHV-1 Induced Genital Disease with a BoHV-4-Based Vector Expressing CpHV-1 gD

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Donofrio, Gaetano ^a   Franceschi, Valentina ^a   Lovero, Angela ^b   Capocefalo, Antonio ^a   Camero, Michele ^b   Losurdo, Michele ^b   Cavirani, Sandro ^a   Marinaro, Mariarosaria ^c   Grandolfo, Erika ^a   Buonavoglia, Canio ^b   Tempesta, Maria ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN D; HERPESVIRUS VECTOR; NEUTRALIZING ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BOVINE HERPES VIRUS; BOVINE HERPES VIRUS 4; CONTROLLED STUDY; DRUG EFFICACY; EMBRYO; EX VIVO STUDY; FEMALE; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNIZATION; IN VIVO STUDY; INOCULATION; NONHUMAN; PRIMARY CELL CULTURE; PROTEIN EXPRESSION; PROVOCATION TEST; SKIN CULTURE; VAGINA DISEASE; VIRAL GENE DELIVERY SYSTEM; VIRUS ISOLATION; VIRUS RECOMBINANT; VIRUS SHEDDING;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CYTOMEGALOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENITAL DISEASES, FEMALE; GLYCOPROTEINS; GOAT DISEASES; GOATS; HEK293 CELLS; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, BOVINE; HUMANS; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PEPTIDES; RECOMBINANT PROTEINS; VARICELLOVIRUS; VIRAL VACCINES; VIRUS SHEDDING;

ANIMALIA; BOVINE HERPESVIRUS 4; CAPRA HIRCUS; CAPRINE HERPESVIRUS 1; HERPESVIRIDAE;

EID: 84871864361     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052758     Document Type: Article

References (44)

1. Davison AJ, (2010) Herpesvirus systematics. Vet Microbiol 143: 52-69.
2. Van der Lugt JJ, Randles JL, (1993) Systemic herpesvirus infection in neonatal goats. J S Afr Vet Assoc 64: 169-171.
3. Tarigan S, Webb RF, Kirkland D, (1987) Caprine herpesvirus from balanoposthitis. Aust Vet J 64: 321.
4. Grewal AS, Wells R, (1986) Vulvovaginitis of goats due to a herpesvirus. Aust Vet J 63: 79-82.
5. Keuser V, Gogev S, Schynts F, Thiry E, (2002) Demonstration of generalized infection with caprine herpesvirus 1 diagnosed in an aborted caprine fetus by PCR. Vet Res Commun 26: 221-226.
6. Engels M, Loepfe E, Wild P, Schraner E, Wyler R, (1987) The genome of caprine herpesvirus 1: genome structure and relatedness to bovine herpesvirus 1. J Gen Virol 68 (Pt 7):: 2019-2023.
7. Tempesta M, Pratelli A, Corrente M, Buonavoglia C, (1999) A preliminary study on the pathogenicity of a strain of caprine herpesvirus-1. Comp Immunol Microbiol Infect Dis 22: 137-143.
8. Tempesta M, Pratelli A, Normanno G, Camero M, Buonavoglia D, et al. (2000) Experimental intravaginal infection of goats with caprine herpesvirus 1. J Vet Med B Infect Dis Vet Public Health 47: 197-201.
9. Tempesta M, Camero M, Sciorsci RL, Greco G, Minoia R, et al. (2004) Experimental infection of goats at different stages of pregnancy with caprine herpesvirus 1. Comp Immunol Microbiol Infect Dis 27: 25-32.
10. Uzal FA, Woods L, Stillian M, Nordhausen R, Read DH, et al. (2004) Abortion and ulcerative posthitis associated with caprine herpesvirus-1 infection in goats in California. J Vet Diagn Invest 16: 478-484.
11. Tempesta M, Pratelli A, Greco G, Martella V, Buonavoglia C, (1999) Detection of caprine herpesvirus 1 in sacral ganglia of latently infected goats by PCR. J Clin Microbiol 37: 1598-1599.
12. Camero M, Crescenzo G, Marinaro M, Tarsitano E, Bellacicco AL, et al. (2010) Cidofovir does not prevent caprine herpesvirus type-1 neural latency in goats. Antivir Ther 15: 785-788.
13. Osorio FA, Reed DE, (1983) Experimental inoculation of cattle with bovine herpesvirus-4: evidence for a lymphoid-associated persistent infection. Am J Vet Res 44: 975-980.
14. Donofrio G, Herath S, Sartori C, Cavirani S, Flammini CF, et al. (2007) Bovine herpesvirus 4 is tropic for bovine endometrial cells and modulates endocrine function. Reproduction 134: 183-197.
15. Donofrio G, Franceschi V, Capocefalo A, Cavirani S, Sheldon IM, (2008) Bovine endometrial stromal cells display osteogenic properties. Reprod Biol Endocrinol 6: 65.
16. McGeoch DJ, Gatherer D, Dolan A, (2005) On phylogenetic relationships among major lineages of the Gammaherpesvirinae. J Gen Virol 86: 307-316.
17. Donofrio G, Cavirani S, Simone T, van Santen VL, (2002) Potential of bovine herpesvirus 4 as a gene delivery vector. J Virol Methods 101: 49-61.
18. Donofrio G, Cavirani S, Vanderplasschen A, Gillet L, Flammini CF, (2006) Recombinant bovine herpesvirus 4 (BoHV-4) expressing glycoprotein D of BoHV-1 is immunogenic and elicits serum-neutralizing antibodies against BoHV-1 in a rabbit model. Clin Vaccine Immunol 13: 1246-1254.
19. Donofrio G, Sartori C, Ravanetti L, Cavirani S, Gillet L, et al. (2007) Establishment of a bovine herpesvirus 4 based vector expressing a secreted form of the bovine viral diarrhoea virus structural glycoprotein E2 for immunization purposes. BMC Biotechnol 7: 68.
20. Donofrio G, Sartori C, Franceschi V, Capocefalo A, Cavirani S, et al. (2008) Double immunization strategy with a BoHV-4-vectorialized secreted chimeric peptide BVDV-E2/BoHV-1-gD. Vaccine 26: 6031-6042.
21. Donofrio G, Franceschi V, Capocefalo A, Taddei S, Sartori C, et al. (2009) Cellular targeting of engineered heterologous antigens is a determinant factor for bovine herpesvirus 4-based vaccine vector development. Clin Vaccine Immunol 16: 1675-1686.
22. Donofrio G, Taddei S, Franceschi V, Capocefalo A, Cavirani S, et al. (2011) Swine adipose stromal cells loaded with recombinant bovine herpesvirus 4 virions expressing a foreign antigen induce potent humoral immune responses in pigs. Vaccine 29: 867-872.
23. Redaelli M, Franceschi V, Capocefalo A, D'Avella D, Denaro L, et al. (2012) Herpes simplex virus type 1 thymidine kinase-armed bovine herpesvirus type 4-based vector displays enhanced oncolytic properties in immunocompetent orthotopic syngenic mouse and rat glioma models. Neuro Oncol 14: 288-301.
24. Keuser V, Detry B, Thiry J, de Fays K, Schynts F, et al. (2006) Characterization of caprine herpesvirus 1 glycoprotein D gene and its translation product. Virus Res 115: 112-121.
25. Marinaro M, Rezza G, Del Giudice G, Colao V, Tarsitano E, et al. (2012) A caprine herpesvirus 1 vaccine adjuvanted with MF59 protects against vaginal infection and interferes with the establishment of latency in goats. PLoS One 7: e34913.
26. Capocefalo A, Franceschi V, Mertens PP, Castillo-Olivares J, Cavirani S, et al. (2010) Expression and secretion of Bluetongue virus serotype 8 (BTV-8)VP2 outer capsid protein by mammalian cells. J Virol Methods 169: 420-424.
27. Redaelli M, Mucignat-Caretta C, Cavaggioni A, Caretta A, D'Avella D, et al. (2010) Bovine herpesvirus 4 based vector as a potential oncolytic-virus for treatment of glioma. Virol J 7: 298.
28. Tempesta M, Camero M, Bellacicco AL, Tarsitano E, Lorusso A, et al. (2007) Caprine herpesvirus 1 vaccine with the LTK63 mutant as a mucosal adjuvant induces strong protection against genital infection in goats. Vaccine 25: 7927-7930.
29. Six A, Banks M, Engels M, Bascunana CR, Ackermann M, (2001) Latency and reactivation of bovine herpesvirus 1 (BHV-1) in goats and of caprine herpesvirus 1 (CapHV-1) in calves. Arch Virol 146: 1325-1335.
30. Thiry J, Tempesta M, Camero M, Tarsitano E, Bellacicco AL, et al. (2006) A live attenuated glycoprotein E negative bovine herpesvirus 1 vaccine induces a partial cross-protection against caprine herpesvirus 1 infection in goats. Vet Microbiol 113: 303-308.
31. Reddy PS, Idamakanti N, Pyne C, Zakhartchouk AN, Godson DL, et al. (2000) The immunogenicity and efficacy of replication-defective and replication-competent bovine adenovirus-3 expressing bovine herpesvirus-1 glycoprotein gD in cattle. Vet Immunol Immunopathol 76: 257-268.
32. Manoj S, Babiuk LA, Littel-van den Hurk SV, (2003) Immunization with a dicistronic plasmid expressing a truncated form of bovine herpesvirus-1 glycoprotein D and the amino-terminal subunit of glycoprotein B results in reduced gB-specific immune responses. Virology 313: 296-307.
33. Gillet L, Schroeder H, Mast J, Thirion M, Renauld JC, et al. (2009) Anchoring tick salivary anti-complement proteins IRAC I and IRAC II to membrane increases their immunogenicity. Vet Res 40: 51.
34. Contag CH, Bachmann MH, (2002) Advances in in vivo bioluminescence imaging of gene expression. Annu Rev Biomed Eng 4: 235-260.
35. Thiry J, Tempesta M, Camero M, Tarsitano E, Muylkens B, et al. (2007) Clinical protection against caprine herpesvirus 1 genital infection by intranasal administration of a live attenuated glycoprotein E negative bovine herpesvirus 1 vaccine. BMC Vet Res 3: 33.
36. Tempesta M, Camero M, Greco G, Pratelli A, Martella V, et al. (2001) A classical inactivated vaccine induces protection against caprine herpesvirus 1 infection in goats. Vaccine 19: 3860-3864.
37. Camero M, Bellacicco AL, Tarsitano E, Decaro N, Martella V, et al. (2007) Intravaginal administration of an inactivated vaccine prevents lesions induced by caprine herpesvirus-1 in goats. Vaccine 25: 1658-1661.
38. Tempesta M, Crescenzo G, Camero M, Bellacicco AL, Tarsitano E, et al. (2008) Assessing the efficacy of cidofovir against herpesvirus-induced genital lesions in goats using different therapeutic regimens. Antimicrob Agents Chemother 52: 4064-4068.
39. Donofrio G, Cavaggioni A, Bondi M, Cavirani S, Flammini CF, et al. (2006) Outcome of bovine herpesvirus 4 infection following direct viral injection in the lateral ventricle of the mouse brain. Microbes Infect 8: 898-904.
40. Buonavoglia C, Tempesta M, Cavalli A, Voigt V, Buonavoglia D, et al. (1996) Reactivation of caprine herpesvirus 1 in latently infected goats. Comp Immunol Microbiol Infect Dis 19: 275-281.
41. Singh M, Sharma AK, (2011) Outgrowth of fibroblast cells from goat skin explants in three different culture media and the establishment of cell lines. In Vitro Cell Dev Biol Anim 47: 83-88.
42. Tempesta M, Camero M, Bellacicco AL, Tarsitano E, Crescenzo G, et al. (2007) Potent inhibition of genital herpesvirus infection in goats by cidofovir. Antivir Ther 12: 977-979.
43. Tempesta M, Camero M, Bellacicco AL, Thiry J, Crescenzo G, et al. (2007) Cidofovir is effective against caprine herpesvirus 1 infection in goats. Antiviral Res 74: 138-141.
44. Elia G, Tarsitano E, Camero M, Bellacicco AL, Buonavoglia D, et al. (2008) Development of a real-time PCR for the detection and quantitation of caprine herpesvirus 1 in goats. J Virol Methods 148: 155-160.