Swine adipose stromal cells loaded with recombinant bovine herpesvirus 4 virions expressing a foreign antigen induce potent humoral immune responses in pigs

Vaccine

Volumn 29, Issue 5, 2011, Pages 867-872

  Donofrio, Gaetano ^a   Taddei, Simone ^a   Franceschi, Valentina ^a   Capocefalo, Antonio ^a   Cavirani, Sandro ^a   Martinelli, Nicola ^b   Ottonello, Simone ^a   Ferrari, Maura ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL EMILIA ROMAGNA   (Italy)

Author keywords

Adipose derived stromal cells; Bovine herpesvirus vector; Pig; Serum neutralizing antibodies

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; HERPESVIRUS VECTOR; IMMUNOGLOBULIN KAPPA CHAIN; NEUTRALIZING ANTIBODY; RECOMBINANT VACCINE; VIRUS GLYCOPROTEIN;

ADIPOSE TISSUE CELL; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BOVINE HERPESVIRUS 1; BOVINE HERPESVIRUS 4; BOVINE VIRAL DIARRHEA VIRUS; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHADINOVIRUS; STROMA CELL; SWINE; TOGAVIRUS; VIRION;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; DIARRHEA VIRUSES, BOVINE VIRAL; GENETIC VECTORS; HERPESVIRUS 4, BOVINE; RECOMBINANT PROTEINS; STROMAL CELLS; SWINE; VACCINATION; VACCINES, SYNTHETIC; VIRAL VACCINES;

EID: 78751574325     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.11.048     Document Type: Article

References (28)

1. Zimmermann W., Broll H., Ehlers B., Buhk H.J., Rosenthal A., Goltz M. Genome sequence of bovine herpesvirus 4, a bovine Rhadinovirus, and identification of an origin of DNA replication. Journal of Virology 2001, 75(February (3)):1186-1194.
2. Bublot M., Dubuisson J., Van Bressem M.F., Danyi S., Pastoret P.P., Thiry E. Antigenic and genomic identity between simian herpesvirus aotus type 2 and bovine herpesvirus type 4. The Journal of General Virology 1991, 72(March (Pt 3)):715-719.
3. Barahona H.H., Melendez L.V., King N.W., Daniel M.D., Fraser C.E., Preville A.C. Herpesvirus aotus type 2: a new viral agent from owl monkeys (Aotus trivirgatus). The Journal of Infectious Diseases 1973, 127(February (2)):171-178.
4. Moreno-Lopez J., Goltz M., Rehbinder C., Valsala K.V., Ludwig H. A bovine herpesvirus (BHV-4) as passenger virus in ethmoidal tumours in Indian cattle. Zentralblatt fur Veterinarmedizin Reihe B Journal of Veterinary Medicine 1989, 36(September (7)):481-486.
5. Egyed L., Kluge J.P., Bartha A. Histological studies of bovine herpesvirus type 4 infection in non-ruminant species. Veterinary Microbiology 1997, 57(September (2-3)):283-289.
6. Czaplicki G., Thiry E. An association exists between bovine herpesvirus-4 seropositivity and abortion in cows. Prevention in Veterinary Medicine 1998, 33(January (1-4)):235-240.
7. Donofrio G., Herath S., Sartori C., Cavirani S., Flammini C.F., Sheldon I.M. Bovine herpesvirus 4 is tropic for bovine endometrial cells and modulates endocrine function. Reproduction 2007, 134(July (1)):183-197.
8. Donofrio G., Ravanetti L., Cavirani S., Herath S., Capocefalo A., Sheldon I.M. Bacterial infection of endometrial stromal cells influences bovine herpesvirus 4 immediate early gene activation: a new insight into bacterial and viral interaction for uterine disease. Reproduction 2008, 136(September (3)):361-366.
9. Donofrio G., Cavirani S., Simone T., van Santen V.L. Potential of bovine herpesvirus 4 as a gene delivery vector. Journal of Virology Methods 2002, 101(March (1-2)):49-61.
10. Gillet L., Daix V., Donofrio G., Wagner M., Koszinowski U.H., China B., et al. Development of bovine herpesvirus 4 as an expression vector using bacterial artificial chromosome cloning. The Journal of General Virology 2005, 86(April (Pt 4)):907-917.
11. Egyed L. Replication of bovine herpesvirus type 4 in human cells in vitro. Journal of Clinical Microbiology 1998, 36(July (7)):2109-2111.
12. Gillet L., Minner F., Detry B., Farnir F., Willems L., Lambot M., et al. Investigation of the susceptibility of human cell lines to bovine herpesvirus 4 infection: demonstration that human cells can support a nonpermissive persistent infection which protects them against tumor necrosis factor alpha-induced apoptosis. Journal of Virology 2004, 78(March (5)):2336-2347.
13. Donofrio G., Franceschi V., Capocefalo A., Cavirani S., Sheldon I.M. Isolation and characterization of bovine herpesvirus 4 (BoHV-4) from a cow affected by post partum metritis and cloning of the genome as a bacterial artificial chromosome. Reproduction in Biology and Endocrinology 2009, 7:83.
14. Donofrio G., Sartori C., Franceschi V., Capocefalo A., Cavirani S., Taddei S., et al. Double immunization strategy with a BoHV-4-vectorialized secreted chimeric peptide BVDV-E2/BoHV-1-gD. Vaccine 2008, 26(November (48)):6031-6042.
15. Donofrio G., Sartori C., Ravanetti L., Cavirani S., Gillet L., Vanderplasschen A., et al. Establishment of a bovine herpesvirus 4 based vector expressing a secreted form of the bovine viral diarrhoea virus structural glycoprotein E2 for immunization purposes. BMC Biotechnology 2007, 7:68.
16. Donofrio G., Manarolla G., Ravanetti L., Sironi G., Cavirani S., Cabassi C.S., et al. Assessment of bovine herpesvirus 4 based vector in chicken. Journal of Virological Methods 2008, 148(March (1-2)):303-306.
17. Gillet L., Schroeder H., Mast J., Thirion M., Renauld J.C., Dewals B., et al. Anchoring tick salivary anti-complement proteins IRAC I and IRAC II to membrane increases their immunogenicity. Veterinary Research 2009, 40(September-October (5)):51.
18. Colleoni S., Bottani E., Tessaro I., Mari G., Merlo B., Romagnoli N., et al. Isolation, growth and differentiation of equine mesenchymal stem cells: effect of donor, source, amount of tissue and supplementation with basic fibroblast growth factor. Veterinary Research Communications 2009, 33(May (8)):10.
19. Donofrio G., Franceschi V., Capocefalo A., Taddei S., Sartori C., Bonomini S., et al. Cellular targeting of engineered heterologous antigens is a determinant factor for bovine herpesvirus 4-based vaccine vector development. Clinical Vaccine and Immunology 2009, 16(November (11)):1675-1686.
20. Mettenleiter T.C. Glycoprotein gIII deletion mutants of pseudorabies virus are impaired in virus entry. Virology 1989, 171(August (2)):623-625.
21. Meliga E., Strem B.M., Duckers H.J., Serruys P.W. Adipose-derived cells. Cell Transplantation 2007, 16(9):963-970.
22. Zuk P.A., Zhu M., Ashjian P., De Ugarte D.A., Huang J.I., Mizuno H., et al. Human adipose tissue is a source of multipotent stem cells. Molecular Biology of the Cell 2002, 13(December (12)):4279-4295.
23. Fulton R.W., Confer A.W., Burge L.J., Perino L.J., d'Offay J.M., Payton M.E., et al. Antibody responses by cattle after vaccination with commercial viral vaccines containing bovine herpesvirus-1, bovine viral diarrhea virus, parainfluenza-3 virus, and bovine respiratory syncytial virus immunogens and subsequent revaccination at day 140. Vaccine 1995, 13(8):725-733.
24. Donofrio G., Cavirani S., Vanderplasschen A., Gillet L., Flammini C.F. Recombinant bovine herpesvirus 4 (BoHV-4) expressing glycoprotein D of BoHV-1 is immunogenic and elicits serum-neutralizing antibodies against BoHV-1 in a rabbit model. Clinical Vaccine and Immunology 2006, 13(November (11)):1246-1254.
25. Gieseke F., Schutt B., Viebahn S., Koscielniak E., Friedrich W., Handgretinger R., et al. Human multipotent mesenchymal stromal cells inhibit proliferation of PBMCs independently of IFNgammaR1 signaling and IDO expression. Blood 2007, 110(September (6)):2197-2200.
26. Aggarwal S., Pittenger M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005, 105(February (4)):1815-1822.
27. Spaggiari G.M., Abdelrazik H., Becchetti F., Moretta L. MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2. Blood 2009, 113(June (26)):6576-6583.
28. Donofrio G., Cavirani S., van Santen V., Flammini C.F. Potential secondary pathogenic role for bovine herpesvirus 4. Journal of Clinical Microbiology 2005, 43(July (7)):3421-3426.