Lineal energy-based evaluation of oxidative DNA damage induced by proton beams and X-rays

International Journal of Radiation Biology

Volumn 89, Issue 1, 2013, Pages 36-43

  Hong, Zhengshan ^a   Kase, Yuki ^b   Moritake, Takashi ^a   Gerelchuluun, Ariungerel ^a   Sun, Lue ^a   Suzuki, Kenshi ^a   Terunuma, Toshiyuki ^a   Yasuoka, Kiyoshi ^a   Kumada, Hiroaki ^a   Anzai, Kazunori ^c   Sakurai, Hideyuki ^a   Sakae, Takeji ^a   Tsuboi, Koji ^a  

^a UNIVERSITY OF TSUKUBA HOSPITAL   (Japan)

^b SHIZUOKA CANCER CENTER   (Japan)

^c NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

DNA oxidative damage; Lineal energy; Proton; X ray

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DNA; HISTONE H2AX; NORPHENAZONE;

AGAR GEL ELECTROPHORESIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MICRODOSIMETRY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTON RADIATION; RADIATION EXPOSURE; TUMOR CELL; X RAY;

ANIMALS; CELL LINE, TUMOR; DEOXYGUANOSINE; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; HISTONES; HUMANS; LINEAR ENERGY TRANSFER; OXIDATIVE STRESS; PHOTONS; PROTONS; RADIOMETRY; X-RAYS;

EID: 84871854041     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2012.715791     Document Type: Article

References (33)

1. Abe S, Kirima K, Tsuchiya K, Okamoto M, Hasegawa T, Houchi H, Yoshizumi M, Tamaki T. 2004. The reaction rate of edaravone (3-methyl-1-phenyl-2- pyrazolin-5-one (MCI-186)) with hydroxyl radical. Chemical & Pharmaceutical Bulletin 52: 186-191.
2. Akagi Y, Ito K, Sawada S. 1993. Radiation-induced apoptosis and necrosis in MOLT-4 cells: A study of dose-effect relationships and their modification. International Journal of Radiation Biology 64: 47-56.
3. Anzai K, Furuse M, Yoshida A, Matsuyama A, Moritake T, Tsuboi K, Ikota N. 2004. In vivo radioprotection of mice by 3-methyl-1- phenyl-2-pyrazolin-5-one (Edaravone; Radicut (R)), a clinical drug. Radiation Research 45: 319-323.
4. Breen AP, Murphy JA. 1995. Reactions of oxyl radicals with DNA. Free Radical Biology and Medicine 18: 1033-1077.
5. Chen J. 2011. Microdosimetric characteristics of proton beams from 50 keV to 200 MeV. Radiation Protection Dosimetry 143: 436-439.
6. Cucinotta FA, Nikjoo H, Goodhead DT. 1998. The effects of delta rays on the number of particle-track traversals per cell in laboratory and space exposures. Radiation Research 150: 115-119.
7. Gerelchuluun A, Hong ZS, Sun L, Suzuki K, Terunuma T, Yasuoka K, Sakae T, Moritake T, Tsuboi K. 2011. Induction of in situ DNA double-strand breaks and apoptosis by 200 MeV protons and 10 MV X-rays in human tumor cell lines. International Journal of Radiation Biology 87: 57-70.
8. Hirayama R, Ito A, Tomita M, Tsukada T, Yatagai F, Noguchi M, Matsumoto Y, Kase Y, Ando K, Okayasu R, Furusawa Y. 2009. Contributions of direct and indirect actions in cell killing by High-LET radiations. Radiation Research 171: 212-218.
9. Ibanez IL, Bracalente C, Molinari BL, Palmieri MA, Policastro L, Kreiner AJ, Burlon AA, Valda A, Navalesi D, Davidson J, Davidson M, V a zquez M, Ozafr an M, Dur an H. 2009. Induction and rejoining of DNA double strand breaks assessed by H2AX phosphorylation in melanoma cells irradiated with proton and lithium beams. International Journal of Radiation Oncology Biology Physics 74: 1226-1235.
10. International Commission on Radiation Units and Measurements (ICRU). 1970. Linear Energy Transfer (ICRU Report 16). Bethesda, MD: ICRU Publications.
11. International Commission on Radiation Units and Measurements (ICRU). 1983. Microdosimetry (ICRU Report 36). Bethesda, MD: ICRU Publications.
12. International Commission on Radiation Units and Measurements (ICRU). 2007. Recording and Reporting Proton-Beam Th erapy (ICRU Report 78). Bethesda, MD: ICRU Publications.
13. Jucha A, Wegierek-Ciuk A, Koza Z, Lisowska H, Wojcik A, Wojewodzka M, LankoffA. 2010. Foci counter: A freely available PC program for quantitative and qualitative analysis of γ-H2AX foci. Mutation Research 696: 16-20.
14. Karlsson KH, Stenerl o w B. 2004. Focus formation of DNA repair proteins in normal and repair-deficient cells irradiated with high-LET ions. Radiation Research 161: 517-527.
15. Kasai H, Hayami H, Yamaizumi Z, Saito H, Nishimura S. 1984. Detection and identification of mutagens and carcinogens as their adducts with guanosine derivatives. Nucleic Acids Research 12: 2127-2136.
16. Kasai H, Nishimura S. 1984. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Research 12: 2137-2145.
17. Kase Y, Kanai T, Matsumoto Y, Furusawa Y, Okamoto H, Asaba T, Sakama M, Shinoda H. 2006. Microdosimetric measurements and estimation of human cell survival for heavy-ion beams. Radiation Research 166: 629-638.
18. Kawai K, Li YS, Kasai H. 2007. Accurate measurement of 8-OH-dG and 8-OH-Gua in mouse DNA, urine and serum: effects of X-ray irradiation. Genes and Environment 29: 107-114.
19. Kinner A, Wu WQ, Staudt C, Iliakis G. 2008. γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Research 36: 5678-5694.
20. Mahrhofer H, Burger S, Oppitz U, Flentje M, Djuzenova CS. 2006. Radiation induced DNA damage and damage repair in human tumor and fibroblast cell lines assessed by histone H2AX phosphorylation. International Journal of Radiation Oncology Biology Physics 64: 573-580.
21. Manova V, GecheffK, Stoilov L. 2006. Efficient repair of bleomycininduced double-strand breaks in barley ribosomal genes. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 601: 179-190.
22. Matsuura T, Egashira Y, Nishio T, Matsumoto Y, Wada M, Koike S, Furusawa Y, Kohno R, Nishioka S, Kameoka S, Tsuchihara K, Kawashima M, Ogino T. 2010. Apparent absence of a proton beam dose rate effect and possible differences in RBE between Bragg peak and plateau. Medical Physics 37: 5376-5381.
23. Milligan JR, Aguilera JA, Ward JF. 1993. Variation of single-strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution. Radiation Research 133: 151-157.
24. Moritake T, Tsuboi K, Anzai K, Ozawa T, Ando K, Nose T. 2003. ESR spin trapping of hydroxyl radicals in aqueous solution irradiated with high-LET carbon-ion beams. Radiation Research 159: 670-675.
25. Okamoto H, Kanai T, Kase Y, Matsumoto Y, Furusawa Y, Fujita Y, Saitoh H, Itami J, Kohno T. 2011. Relation between lineal energy distribution and relative biological effectiveness for photon beams according to the microdosimetric kinetic model. Radiation Research 52: 75-81.
26. Paganetti H. 2002. Nuclear interactions in proton therapy: Dose and relative biological effect distributions originating from primary and secondary particles. Physics in Medicine and Biology 47: 747-764.
27. Rollet S, Autischer M, Beck P, Latocha M. 2007. Measurement and simulation of lineal energy distribution at the CERN high energy facility with a tissue equivalent proportional counter. Radiation Protection Dosimetry 125: 425-428.
28. Roots R, Holley W, Chatterjee A, Irizarry M, Kraft G. 1990. The formation of strand breaks in DNA after high-LET irradiation: A comparison of data from in vitro and cellular systems. International Journal of Radiation Biology 58: 55-69.
29. Sato T, Watanabe R, Niita K. 2006. Development of a calculation method for estimating specific energy distribution in complex radiation fields. Radiation Protection Dosimetry 122: 41-45.
30. Sutherland BM, Bennett PV, Sutherland JC. 1999. DNA damage quantitation by alkaline gel electrophoresis. Methods in Molecular Biology 113: 183-202.
31. Toyokuni S, Sagripanti JL. 1996. Association between 8-hydroxy-2'- deoxyguanosine formation and DNA strand breaks mediated by copper and iron. Free Radical Biology and Medicine 20: 859-864.
32. Toyokuni S, Sagripanti JL. 1999. Iron chelators modulate the production of DNA strand breaks and 8-hydroxy-2'-deoxyguanosine. Free Radical Research 31: 123-128.
33. Wambersie A. 1999. RBE, reference RBE and clinical RBE: Applications of these concepts in hadron therapy. Strahlentherapie Und Onkologie 175: 39-34.