Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate

Journal of Mass Spectrometry

Volumn 47, Issue 12, 2012, Pages 1594-1600

  Martens Lobenhoffer, Jens ^a   Rodionov, Roman N ^b   Bode Böger, Stefanie M ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

ADMA; AGXT2; DMGV; enzyme activity; mouse

Indexed keywords

ADMA; AGXT2; ASYMMETRIC DIMETHYLARGININE; BIOLOGICAL RESEARCH; CHROMATOGRAPHIC SEPARATIONS; COEFFICIENTS OF VARIATIONS; DMGV; ENZYMATIC PRODUCTION; INTERNAL STANDARDS; KIDNEY TISSUES; L-ARGININE; MOLECULAR POSITION; MOUSE; MOUSE LIVER; MOUSE TISSUES; POROUS GRAPHITIC CARBON; PRODUCTION RATES; RENAL EXCRETION; TANDEM MASS SPECTROMETRIC DETECTION; TISSUE HOMOGENATES; TOTAL PROTEIN; VALERIC ACIDS;

CARBON; DEUTERIUM; ENZYME ACTIVITY; ENZYMES; LIQUID CHROMATOGRAPHY; MAMMALS; NITRIC OXIDE; POROUS MATERIALS; PROTEINS; TISSUE;

AMINO ACIDS;

ALANINE GLYOXYLATE AMINOTRANSFERASE; ALANINE GLYOXYLATE AMINOTRANSFERASE 2; CARBON; DEUTERIUM; N(G),N(G) DIMETHYLARGININE; STABLE ISOTOPE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

ANIMAL TISSUE; ARTICLE; COLUMN CHROMATOGRAPHY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MECHANISM; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; KIDNEY PARENCHYMA; LIVER; LIVER LEVEL; MOUSE; NONHUMAN; POROSITY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; TISSUE HOMOGENATE; TISSUE LEVEL;

ANIMALS; ARGININE; CHROMATOGRAPHY, LIQUID; ENZYME STABILITY; GUANIDINES; HYDROGEN-ION CONCENTRATION; ISOTOPE LABELING; KETO ACIDS; KIDNEY; LIVER; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; NITRIC OXIDE; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; TRANSAMINASES;

MUS;

EID: 84871836964     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.3125     Document Type: Article

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