Are low levels of 25-hydroxyvitamin D a risk factor for cardiovascular diseases or malignancies in renal transplantation?

Nephrology Dialysis Transplantation

Volumn 27, Issue SUPPL.4, 2012, Pages

  Marcén, Roberto ^a   Jimenez, Sara ^a   Fernández Rodriguez, Ana ^a   Galeano, Cristina ^a   Villafruela, Juan José ^a   Gomis, Antonio ^a   Teruel, José Luis ^a   Quereda, Carlos ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

25(OH)D; cardiovascular diseases; kidney transplantation; malignancies; vitamin D status

Indexed keywords

25 HYDROXYVITAMIN D;

ADULT; ARTICLE; BREAST CANCER; CANCER RISK; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; COLON CANCER; CORONARY ARTERY DISEASE; DATA BASE; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GRAFT RECIPIENT; HEART ARRHYTHMIA; HEART FAILURE; HUMAN; INCIDENCE; KIDNEY CANCER; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; LUNG CANCER; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MINERAL METABOLISM; NON MELANOMA SKIN CANCER; OBSERVATIONAL STUDY; PERIPHERAL VASCULAR DISEASE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; RISK ASSESSMENT; RISK FACTOR; UNIVARIATE ANALYSIS; URINARY TRACT CANCER; VITAMIN D DEFICIENCY;

CARDIOVASCULAR DISEASES; FEMALE; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; NEOPLASMS; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84871831188     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs508     Document Type: Article

References (26)

1. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008; 87: 1080S-1086S
2. Lee JH, O'Keefe JH, Bell D et al. Vitamin D deficiency. An important, common and easily treatable cardiovascular risk factor? J Am Coll Cardiol 2008; 52: 1949-1958
3. Hollis BW. Short-term consequences and concerns regarding valid assessment of vitamin D deficiency: comparison of recent food supplementation and clinical guidance reports. Curr Opin Clin Nutr Metab Care 2011; 14: 598-604
4. Martins D, Wolf M, Pan D et al. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States. Data from the third national health and nutrition examination survey. Arch Intern Med 2007; 167: 1159-1165
5. Dobnig H, Pilz S, Scharnagi H et al. Independent association of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels with all cause and cardiovascular mortality. Arch Intern Med 2008; 168: 1340-1349
6. Makariou S, Liberopoulos EN, Elisaf M et al. Novel roles of vitamin D in disease: what is new in 2011? Eur J Intern Med 2011; 22: 355-362
7. Wang TJ, Pencina MJ, Booth SL et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation 2008; 117: 503
8. Mehrotra R, Kermah D, Budoff M et al. Hypovitaminosis D in chronic kidney disease. Clin J Am Soc Nephrol 2008; 3: 1144-1151
9. Pilz S, Tomaschitz A, Friedl C et al. Vitamin D mortality in chronic kidney disease. Nephrol Dial Transplant 2011; 26: 3603-3609
10. Stavroulopoulos A, Cassidy MJD, Prter CJ et al. Vitamin status in renal transplant recipients. Am J Transplant 2007; 7: 2546-2552
11. Ewers B, Gasbjerg A, Morlgaard C et al. Vitamin D status in kidney transplant patients: need for intensified routine supplementation. Am J Clin Nutr 2008; 87: 431-437
12. Marcén R, Ponte B, Rodriguez-Mendiola N et al. Vitamin D deficiency in kidney transplant recipients: risk factors and effects of vitamin D supplements. Transplant Proc 2009; 41: 2388-2390
13. Rigatto C, Parfrey P, Foley R et al. Congestive heart failure in renal transplant recipients: risk factors, outcomes, and relationship with ischemic heart disease. J Am Soc Nephrol 2002; 13: 1084-1090
14. Marcén R. Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection. Drugs 2009; 69: 2227-2243
15. Ducloux D, Courivaud C, Baumould J et al. Pretransplant serum vitamin D levels and risk of cancer after renal transplantation. Transplantation 2008; 85: 1755-1759
16. Giovannuchi E, Liu Y, Hollis BW et al. 25-hydroxivitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 2008; 168: 1174
17. Pilz S, Dobnig H, Nijpels G et al. Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography. J Clin Endocrinol Metab 2008; 93: 3927
18. Zitterman A, Iodice S, Pilz S et al. Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies. Am J Clin Nutr 2012; 95: 91-100
19. Ravani P, Malberti F, Tripepi G et al. Vitamin D levels and patient outcome in chronic kidney disease. Kidney Int 2009; 75: 88
20. Artaza JN, Mehrotra R, Norris KC. Vitamin D and the cardiovascular system. Clin J Am Soc Nephrol 2009; 4: 1515-1522
21. Lee DR, Kong JM, Cho KI et al. Impact of vitamin D on proteinuria, insulin resistance, and cardiovascular parameters in kidney transplant recipients. Transplant Proc 2011; 43: 3723-3729
22. Lappe JM, Travers-Gustafson D, Davies KM et al. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr 2007; 85: 1586-1591
23. Chung M, Lee J, Terasawa T et al. Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the US preventive services task force. Ann Intern Med 2011; 155: 827-838
24. KDIGO clinical practice guideline for the care of kidney transplant recipients. Transplant bone disease. Am J Transplant 2009; 76: S93-S96
25. Autier P, Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 2007; 167: 1730
26. Kandula P, Dobre M, Schold JD et al. Vitamin D supplementation in chronic kidney disease: a systematic review and meta-analysis of observational studies and randomized controlled trials. Clin J Am Soc Nephrol 2011; 6: 50-62