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Volumn 2, Issue 12, 2011, Pages 2311-2313

The first example of the direct asymmetric conjugate addition of aldehydes to a methylenemalonate promoted by an axially chiral amino diol catalyst

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EID: 84871826264     PISSN: 20416520     EISSN: 20416539     Source Type: Journal    
DOI: 10.1039/c1sc00453k     Document Type: Article
Times cited : (17)

References (34)
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    • The reaction between an enamine and methyl acrylate requires a high temperature and long reaction time. See
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    • Sulzer-Mossé, S.1    Alexakis, A.2
  • 14
    • 25444470782 scopus 로고    scopus 로고
    • For organocatalytic asymmetric conjugate additions to α-substituted acrylates and β-substituted methylenemalonates, see
    • Y. Chi S. H. Gellman Org. Lett. 2005 7 4253
    • (2005) Org. Lett. , vol.7 , pp. 4253
    • Chi, Y.1    Gellman, S.H.2
  • 24
    • 0037419866 scopus 로고    scopus 로고
    • The NMR analysis revealed that pyrrolidine in THF-d8 was completely consumed by equimolar 6 after 4 h of stirring at room temperature. Under identical conditions, 81% of (S)- 1 and 88% of (S)- 5 remained intact
    • S. P. Brown N. C. Goodwin D. W. C. MacMillan J. Am. Chem. Soc. 2003 125 1192
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 1192
    • Brown, S.P.1    Goodwin, N.C.2    MacMillan, D.W.C.3
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    • 84871825293 scopus 로고    scopus 로고
    • WO, 113337
    • WO, 113337, 2004
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  • 31
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    • WO, 113328
    • WO, 113328, 2004
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  • 33
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    • WO, 074083
    • WO, 074083, 2003
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.