Epigenetic repression of chemokine expression at the maternal-fetal interface as a mechanism of feto-maternal tolerance;Répression épigénétique de l'expression des chimiokines àl'interface mère-foetus un mécanisme de tolérance du foetus

Medecine/Sciences

Volumn 28, Issue 12, 2012, Pages 1037-1039

  Nancy, Patrice ^a   Erlebacher, Adrian ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE;

ARTICLE; BIOLOGICAL MODEL; FEMALE; FETOMATERNAL TRANSFUSION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC EPIGENESIS; GENETICS; HISTOCOMPATIBILITY; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; NIDATION; PHYSIOLOGY; PLACENTA; PREGNANCY; T LYMPHOCYTE;

CHEMOKINES; EMBRYO IMPLANTATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HISTOCOMPATIBILITY, MATERNAL-FETAL; HUMANS; IMMUNE TOLERANCE; MATERNAL-FETAL EXCHANGE; MODELS, BIOLOGICAL; PLACENTA; PREGNANCY; T-LYMPHOCYTES;

EID: 84871825966     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/20122812005     Document Type: Article

References (10)

1. Trowsdale J, Betz AG. Mother's little helpers: mechanisms of maternal-fetal tolerance. Nat Immunol 2006; 7 : 241-6.
2. Erlebacher A. Immune surveillance of the maternal/ fetal interface: controversies and implications. Trends Endocrinol Metab 2010; 21 : 428-34.
3. Erlebacher A, Vencato D, Price KA, et al. Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J Clin Invest 2007; 117 : 1399-411.
4. Nancy P, Tagliani E, Tay CS, et al. Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface. Science 2012; 336 : 1317-21.
5. Bromley SK, Mempel TR, Luster AD. Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat Immunol 2008; 9 : 970-80.
6. Ohmori Y, Hamilton TA. The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha. J Immunol 1995; 154 : 5235-44.
7. Hiroi M, Ohmori Y. The transcriptional coactivator CREB-binding protein cooperates with STAT1 and NF-kappa B for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferongamma gene. J Biol Chem 2003; 278 : 651-60.
8. Campos EI, Reinberg D. Histones: annotating chromatin. Annu Rev Genet 2009; 43 : 559-99.
9. Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011; 469 : 343-9.
10. Coulombel L. Tolérance maternelle du foetus : le rôle d'un enhancer de Foxp3 lors de l'émergence des mammifères euthériens. Med Sci (Paris) 2012; 28 : 826-8.