Phagocytes mediate targeting of iron oxide nanoparticles to tumors for cancer therapy

Integrative Biology (United Kingdom)

Volumn 5, Issue 1, 2013, Pages 159-171

  Toraya Brown, Seiko ^a   Sheen, Mee Rie ^a   Baird, Jason R ^a   Barry, Stephen ^b   Demidenko, Eugene ^a   Turk, Mary Jo ^a,c   Hoopes, P Jack ^a,c,d   Conejo Garcia, Jose R ^e   Fiering, Steven ^a,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b Aspen Medisys LLC   (United States)

^c NORRIS COTTON CANCER CENTER   (United States)

^d DARTMOUTH COLLEGE   (United States)

^e WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IRON OXIDE NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG;

ALTERNATING MAGNETIC FIELD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL DESTRUCTION; CONTROLLED STUDY; FEMALE; MAGNETIC FIELD; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; OVARY CANCER; PERITONEUM CANCER; PHAGOCYTE; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT;

EID: 84871806799     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c2ib20180a     Document Type: Article

References (28)

1. A. Chavez-Blanco V. Perez-Sanchez A. Gonzalez-Fierro et al., HER2 expression in cervical cancer as a potential therapeutic target BMC Cancer 2004 4 59
2. D. B. Kirpotin D. C. Drummond Y. Shao et al., Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models Cancer Res. 2006 66 6732 6740
3. M. H. Mendonca Dias P. C. Lauterbur Ferromagnetic particles as contrast agents for magnetic resonance imaging of liver and spleen Magn. Reson. Med. 1986 3 328 330
4. S. Fisher W. B. Riley C. D. Shorey Studies on the mechanism of increased splenic particle uptake in mice after the injection of some finely divided agents J. Pathol. Bacteriol. 1968 96 463 471
5. R. L. Hong C. J. Huang Y. L. Tseng et al., Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial? Clin. Cancer Res. 1999 5 3645 3652
6. J. R. Conejo-Garcia F. Benencia M. C. Courreges et al., Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A Nat. Med. (N. Y.) 2004 10 950 958
7. K. F. Roby C. C. Taylor J. P. Sweetwood et al., Development of a syngeneic mouse model for events related to ovarian cancer Carcinogenesis 2000 21 585 591
8. J. R. Cubillos-Ruiz X. Engle U. K. Scarlett et al., Polyethylenimine- based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity J. Clin. Invest. 2009 119 2231 2244
9. K. D. Phipps A. P. Surette P. A. O'Connell D. M. Waisman Plasminogen receptor S100A10 is essential for the migration of tumor-promoting macrophages into tumor sites Cancer Res. 2011 71 6676 6683
10. P. M. Kelly R. S. Davison E. Bliss J. O. McGee Macrophages in human breast disease: a quantitative immunohistochemical study Br. J. Cancer 1988 57 174 177
11. C. Murdoch A. Giannoudis C. E. Lewis Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues Blood 2004 104 2224 2234
12. R. Ivkov S. J. DeNardo W. Daum et al., Application of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancer Clin. Cancer Res. 2005 11 7093s 7103s
13. W. H. De Jong P. J. Borm Drug delivery and nanoparticles:applications and hazards Int. J. Nanomed. 2008 3 133 149
14. M. Settles M. Etzrodt K. Kosanke et al., Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles PLoS One 2011 6 e25197
15. C. R. Patra S. S. Abdel Moneim E. Wang et al., In vivo toxicity studies of europium hydroxide nanorods in mice Toxicol. Appl. Pharmacol. 2009 240 88 98
16. T. Xia M. Kovochich J. Brant et al., Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm Nano Lett. 2006 6 1794 1807
17. D. M. Katschinski K. Boos S. G. Schindler J. Fandrey Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis J. Biol. Chem. 2000 275 21094 21098
18. J. Frank D. K. Kelleher A. Pompella O. Thews H. K. Biesalski P. Vaupel Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase Cancer Res. 1998 58 2693 2698
19. C. W. Helm J. C. States Enhancing the efficacy of cisplatin in ovarian cancer treatment-could arsenic have a role J. Ovarian Res. 2009 2 2
20. P. Wust B. Hildebrandt G. Sreenivasa et al., Hyperthermia in combined treatment of cancer Lancet Oncol. 2002 3 487 497
21. E. Huarte J. R. Cubillos-Ruiz Y. C. Nesbeth et al., Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity Cancer Res. 2008 68 7684 7691
22. Q. Liu B. Zhai W. Yang et al., Abrogation of local cancer recurrence after radiofrequency ablation by dendritic cell-based hyperthermic tumor vaccine Mol. Ther. 2009 17 2049 2057
23. H. Bendz S. C. Ruhland M. J. Pandya et al., Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling J. Biol. Chem. 2007 282 31688 31702
24. R. J. Binder P. K. Srivastava Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells Nat. Immunol. 2005 6 593 599
25. R. Suto P. K. Srivastava A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides Science 1995 269 1585 1588
26. M. Breloer B. Dorner S. H. More T. Roderian B. Fleischer A. von Bonin Heat shock proteins as "danger signals": eukaryotic Hsp60 enhances and accelerates antigen-specific IFN-gamma production in T cells Eur. J. Immunol. 2001 31 2051 2059
27. N. Saltan H. M. Kutlu D. Hur A. Iscan R. Say Interaction of cancer cells with magnetic nanoparticles modified by methacrylamido-folic acid Int. J. Nanomed. 2011 6 477 484
28. C. Leuschner C. S. Kumar W. Hansel W. Soboyejo J. Zhou J. Hormes LHRH-conjugated magnetic iron oxide nanoparticles for detection of breast cancer metastases Breast Cancer Res. Treat. 2006 99 163 176