MicroRNA-138 Suppresses Neutrophil Gelatinase-Associated Lipocalin Expression and Inhibits Tumorigenicity

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Lee, Ying Chu ^a   Tzeng, Woan Fang ^b   Chiou, Tzeon Jye ^c,d   Chu, Sin Tak ^a,e  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER ANTIBODY; MICRORNA; MICRORNA 138; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER GROWTH; CANCER INVASION; CARCINOGENICITY; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOMETRIUM CARCINOMA; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; METASTASIS; MOUSE; NONHUMAN; PANCREAS CARCINOMA; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; GELATINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIPOCALINS; MICE; MICE, NUDE; MICRORNAS; NEUTROPHILS; TRANSFECTION;

MUS MUSCULUS;

EID: 84871804460     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052979     Document Type: Article

References (23)

1. Kjeldsen L, Johnsen AH, Sengelov H, Borregaard N, (1993) Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J Biol Chem 268: 10425-10432.
2. Lin HH, Li WW, Lee YC, Chu ST, (2007) Apoptosis induced by uterine 24p3 protein in endometrial carcinoma cell line. Toxicology 234: 203-215.
3. Tong Z, Wu X, Ovcharenko D, Zhu J, Chen CS, et al. (2005) Neutrophil gelatinase-associated lipocalin as a survival factor. Biochem J 391: 441-448.
4. Bauer M, Eickhoff JC, Gould MN, Mundhenke C, Maass N, et al. (2008) Neutrophil gelatinase-associated lipocalin (NGAL) is a predictor of poor prognosis in human primary breast cancer. Breast Cancer Res Treat 108: 389-397.
5. Moniaux N, Chakraborty S, Yalniz M, Gonzalez J, Shostrom VK, et al. (2008) Early diagnosis of pancreatic cancer: neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia. Br J Cancer 98: 1540-1547.
6. Hu L, Hittelman W, Lu T, Ji P, Arlinghaus R, et al. (2009) NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells. Lab Invest 89: 531-548.
7. Leng X, Wu Y, Arlinghaus RB, (2011) Relationships of lipocalin 2 with breast tumorigenesis and metastasis. J Cell Physiol 226(2): 309-14.
8. Maziere P, Enrighy AJ, (2007) Prediction of microRNA targets. Drug Dis Today 12: 452-458.
9. Zimmerman AL, Wu S, (2011) MicroRNAs, cancer and cancer stem cells. Cancer Lett 300(1): 10-9.
10. Taft RJ, Pang KC, Morcer TR, Dinger M, Mattick JS, (2010) Non-coding RNAs: regulators of disease. J Pathol 220(2): 126-3911.
11. Lim R, Ahmed N, Borregaard N, Riley C, Wafai R, et al. (2007) Neutrophil gelatinase-associated lipocalin (NGAL) an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced epithelio-mesenchymal transition. Int J Can 120: 2426-2434.
12. Thiery JP, (2003) Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 15: 740-746.
13. Liu X, Wang C, Chen Z, Jin Y, Wang Y, et al. (2011) MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. Biocem J 440: 23-31.
14. Jiang L, Dai Y, Liu X, Wang C, Wang A, et al. (2011) Identification and experimental validation of G protein alpha inhibiting activity polypeptide 2 (GNAI2) as a microRNA-138 target in tongue squamous cell carcinoma. Hum Genet 129(2): 189-197.
15. Brizova H, Kalinova M, krskova L, Mrhalova M, Kodet R, (2010) A novel quantitative PCR o proliferation markers (Ki-67, topoisomerase IIα, and TPX2): an immunohistochemical correlation, testing and optimizing for mantle cell lymphoma. Virchows Arch 456: 671-679.
16. Rodriguez LG, Wu X, Guan JL, (2005) Wound-healing assay. Methods Mol Biol 294: 23-29.
17. Bratt T, (2000) Lipoealins and cancer Biochim. Biophys Acta 1482: 318-326.
18. Stoesz SP, Friedl A, Hagg JD, Lindstrom MJ, Clark GM, et al. (1998) Heterogeneous expression of the lipocalin NGAL in primary breast cancers. Int J Can 79: 565-572.
19. Lim R, Ahmed N, Borregaard N, Riley C, Wafai R, et al. (2007) NGAL an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced EMT. Int J Can 120: 2426-2434.
20. Friedl A, Stoesz SP, Buckley P, Gould MN, (1999) NGAL in normal and neoplastic human tissues. Cell type-specific pattern of expression Histochem J 31: 433-441.
21. Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lenaeelcel W, et al. (2002) Identification of tissue-specific Micro RNAs from mouse. Cur Biol 12: 735-739.
22. Liu X, Wang C, Chen Z, Jin Y, Wang Y, et al. (2011) MicroRNA-138 suppresses epithelial-inesenchymal transition in squamous cell carcinoma cell lives. Biochem J 440: 23-31.
23. Wang B, Wang H, Yang Z, (2012) MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R. PLoS ONE 7(10): e47053.