메뉴 건너뛰기




Volumn 56, Issue 2, 2013, Pages 272-282

Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: A systematic review and meta-analysis

Author keywords

doripenem; ertapenem; imipenem; meropenem

Indexed keywords

CARBAPENEM DERIVATIVE; CILASTATIN PLUS IMIPENEM; DORIPENEM; ERTAPENEM; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM;

EID: 84871803445     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cis857     Document Type: Review
Times cited : (235)

References (56)
  • 1
    • 68349097632 scopus 로고    scopus 로고
    • The use of carbapenems in the treatment of serious infections
    • Baughman RP. The use of carbapenems in the treatment of serious infections. J Intensive Care Med 2009; 24:230-41.
    • (2009) J Intensive Care Med , vol.24 , pp. 230-241
    • Baughman, R.P.1
  • 3
    • 79960006483 scopus 로고    scopus 로고
    • Elderly patients with community-acquired pneumonia: Optimal treatment strategies
    • Thiem U, Heppner HJ, Pientka L. Elderly patients with community-acquired pneumonia: optimal treatment strategies. Drugs Aging 2011; 28:519-37.
    • (2011) Drugs Aging , vol.28 , pp. 519-537
    • Thiem, U.1    Heppner, H.J.2    Pientka, L.3
  • 4
    • 16244372376 scopus 로고    scopus 로고
    • Comparison of the pharmacodynamics of meropenem in patients with ventilator-associated pneumonia following administration by 3-hour infusion or bolus injection
    • DOI 10.1128/AAC.49.4.1337-1339.2005
    • Jaruratanasirikul S, Sriwiriyajan S, Punyo J. Comparison of the phar-macodynamics of meropenem in patients with ventilator-associated pneumonia following administration by 3-hour infusion or bolus injection. Antimicrob Agents Chemother 2005; 49:1337-9. (Pubitemid 40463358)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.4 , pp. 1337-1339
    • Jaruratanasirikul, S.1    Sriwiriyajan, S.2    Punyo, J.3
  • 5
    • 23844553605 scopus 로고    scopus 로고
    • Population pharmacokinetics and pharmacodynamics of piperacillin/ tazobactam in patients with complicated intra-abdominal infection
    • DOI 10.1093/jac/dki243
    • Li C, Kuti JL, Nightingale CH, Mansfield DL, Dana A, Nicolau DP. Population pharmacokinetics and pharmacodynamics of piperacillin/tazobactam in patients with complicated intra-abdominal infection. J Antimicrob Chemother 2005; 56:388-95. (Pubitemid 41158530)
    • (2005) Journal of Antimicrobial Chemotherapy , vol.56 , Issue.2 , pp. 388-395
    • Li, C.1    Kuti, J.L.2    Nightingale, C.H.3    Mansfield, D.L.4    Dana, A.5    Nicolau, D.P.6
  • 6
    • 9644268224 scopus 로고    scopus 로고
    • Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation
    • DOI 10.1128/AAC.48.12.4718-4724.2004
    • Lodise TP Jr, Lomaestro B, Rodvold KA, Danziger LH, Drusano GL. Pharmacodynamic profiling of piperacillin in the presence of tazobac-tam in patients through the use of population pharmacokinetic models and Monte Carlo simulation. Antimicrob Agents Chemother 2004; 48:4718-24. (Pubitemid 39577677)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.12 , pp. 4718-4724
    • Lodise Jr., T.P.1    Lomaestro, B.2    Rodvold, K.A.3    Danziger, L.H.4    Drusano, G.L.5
  • 7
    • 72449120921 scopus 로고    scopus 로고
    • First-dose and steady-state population pharmacokinetics and pharmacody-namics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis
    • Roberts JA, Kirkpatrick CM, Roberts MS, Dalley AJ, Lipman J. First-dose and steady-state population pharmacokinetics and pharmacody-namics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. Int J Antimicrob Agents 2010; 35:156-63.
    • (2010) Int J Antimicrob Agents , vol.35 , pp. 156-163
    • Roberts, J.A.1    Kirkpatrick, C.M.2    Roberts, M.S.3    Dalley, A.J.4    Lipman, J.5
  • 9
    • 66449092115 scopus 로고    scopus 로고
    • A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics
    • Roberts JA, Webb S, Paterson D, Ho KM, Lipman J. A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics. Crit Care Med 2009; 37:2071-8.
    • (2009) Crit Care Med , vol.37 , pp. 2071-2078
    • Roberts, J.A.1    Webb, S.2    Paterson, D.3    Ho, K.M.4    Lipman, J.5
  • 10
    • 79959337263 scopus 로고    scopus 로고
    • Does prolonged beta-lactam infusion improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials
    • Tamma PD, Putcha N, Suh YD, Van Arendonk KJ, Rinke ML. Does prolonged beta-lactam infusion improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials. BMC Infect Dis 2011; 11:181.
    • (2011) BMC Infect Dis , vol.11 , pp. 181
    • Tamma, P.D.1    Putcha, N.2    Suh, Y.D.3    Van Arendonk, K.J.4    Rinke, M.L.5
  • 11
    • 23944504296 scopus 로고    scopus 로고
    • Continuous versus intermittent intravenous administration of antibiotics: A meta-analysis of randomised controlled trials
    • DOI 10.1016/S1473-3099(05)70218-8, PII S1473309905702188
    • Kasiakou SK, Sermaides GJ, Michalopoulos A, Soteriades ES, Falagas ME. Continuous versus intermittent intravenous administration of antibiotics: a meta-analysis of randomised controlled trials. Lancet Infect Dis 2005; 5:581-9. (Pubitemid 41196757)
    • (2005) Lancet Infectious Diseases , vol.5 , Issue.9 , pp. 581-589
    • Kasiakou, S.K.1    Sermaides, G.J.2    Michalopoulos, A.3    Soteriades, E.S.4    Falagas, M.E.5
  • 12
    • 84857027205 scopus 로고    scopus 로고
    • Evaluating outcomes associated with alternative dosing strategies for piperacillintazobactam: A qualitative systematic review
    • Mah GT, Mabasa VH, Chow I, Ensom MH. Evaluating outcomes associated with alternative dosing strategies for piperacillin/tazobactam: a qualitative systematic review. Ann Pharmacother 2012; 46:265-75.
    • (2012) Ann Pharmacother , vol.46 , pp. 265-275
    • Mah, G.T.1    Mabasa, V.H.2    Chow, I.3    Ensom, M.H.4
  • 14
    • 80855139559 scopus 로고    scopus 로고
    • Retrospective study of prolonged versus intermittent infusion piperacillin-tazobactam and meropenem in intensive care unit patients at an academic medical center
    • Dow RJ, Rose WE, Fox BC, Thorpe JM, Fish JT. Retrospective study of prolonged versus intermittent infusion piperacillin-tazobactam and meropenem in intensive care unit patients at an academic medical center. Infect Dis Clin Pract 2011; 19:413-7.
    • (2011) Infect Dis Clin Pract , vol.19 , pp. 413-417
    • Dow, R.J.1    Rose, W.E.2    Fox, B.C.3    Thorpe, J.M.4    Fish, J.T.5
  • 16
    • 0036206559 scopus 로고    scopus 로고
    • Clinical efficacy and pharmacoeconomics of a continuous-infusion piperacillin-tazobactam program in a large community teaching hospital
    • Grant EM, Kuti JL, Nicolau DP, Nightingale C, Quintiliani R. Clinical efficacy and pharmacoeconomics of a continuous-infusion piperacil-lin-tazobactam program in a large community teaching hospital. Pharmacotherapy 2002; 22:471-83. (Pubitemid 34270031)
    • (2002) Pharmacotherapy , vol.22 , Issue.4 , pp. 471-483
    • Grant, E.M.1    Kuti, J.L.2    Nicolau, D.P.3    Nightingale, C.4    Quintiliani, R.5
  • 17
    • 34547683913 scopus 로고    scopus 로고
    • Clinical efficacy of prolonged (4 hour) drip infusion of meropenem against severe pneumonia
    • Itabashi S. Clinical efficacy of prolonged (4 hour) drip infusion of meropenem against severe pneumonia. Japan J Antibiot 2007; 60:161-70. (Pubitemid 47217242)
    • (2007) Japanese Journal of Antibiotics , vol.60 , Issue.3 , pp. 161-170
    • Itabashi, S.1
  • 18
    • 33750592553 scopus 로고    scopus 로고
    • Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection
    • DOI 10.1128/AAC.00329-06
    • Lau WK, Mercer D, Itani KM, et al. Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection. Antimicrob Agents Chemother 2006; 50:3556-61. (Pubitemid 44684865)
    • (2006) Antimicrobial Agents and Chemotherapy , vol.50 , Issue.11 , pp. 3556-3561
    • Lau, W.K.1    Mercer, D.2    Itani, K.M.3    Nicolau, D.P.4    Kuti, J.L.5    Mansfield, D.6    Dana, A.7
  • 19
    • 33846442436 scopus 로고    scopus 로고
    • Piperacillin-tazobactam for Pseudomonas aeruginosa infection: Clinical implications of an extended-infusion dosing strategy
    • DOI 10.1086/510590
    • Lodise TP Jr, Lomaestro B, Drusano GL. Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy. Clin Infect Dis 2007; 44:357-63. (Pubitemid 46147617)
    • (2007) Clinical Infectious Diseases , vol.44 , Issue.3 , pp. 357-363
    • Lodise Jr., T.P.1    Lomaestro, B.2    Drusano, G.L.3
  • 20
    • 63149188101 scopus 로고    scopus 로고
    • Clinical cure of ventilator-associated pneumonia treated with pipera-cillin/tazobactam administered by continuous or intermittent infusion
    • Lorente L, Jimenez A, Martin MM, Iribarren JL, Jimenez JJ, Mora ML. Clinical cure of ventilator-associated pneumonia treated with pipera-cillin/tazobactam administered by continuous or intermittent infusion. Int J Antimicrob Agents 2009; 33:464-8.
    • (2009) Int J Antimicrob Agents , vol.33 , pp. 464-468
    • Lorente, L.1    Jimenez, A.2    Martin, M.M.3    Iribarren, J.L.4    Jimenez, J.J.5    Mora, M.L.6
  • 21
    • 33144478109 scopus 로고    scopus 로고
    • Meropenem by continuous versus intermittent infusion in ventilator-associated pneumonia due to gram-negative bacilli
    • DOI 10.1345/aph.1G467
    • Lorente L, Lorenzo L, Martin MM, Jimenez A, Mora ML. Meropenem by continuous versus intermittent infusion in ventilator-associated pneumonia due to gram-negative bacilli. Ann Pharmacother 2006; 40:219-23. (Pubitemid 43269850)
    • (2006) Annals of Pharmacotherapy , vol.40 , Issue.2 , pp. 219-223
    • Lorente, L.1    Lorenzo, L.2    Martin, M.M.3    Jimenez, A.4    Mora, M.L.5
  • 22
    • 70349329921 scopus 로고    scopus 로고
    • Clinical effects of continuous infusion and intermittent infusion of meropenem on bacterial pneumonia in the elderly
    • Okimoto N, Ishiga M, Nanba F, et al. Clinical effects of continuous infusion and intermittent infusion of meropenem on bacterial pneumonia in the elderly. Nihon Kokyuki Gakkai Zasshi 2009; 47:553-7.
    • (2009) Nihon Kokyuki Gakkai Zasshi , vol.47 , pp. 553-557
    • Okimoto, N.1    Ishiga, M.2    Nanba, F.3
  • 23
    • 66449083294 scopus 로고    scopus 로고
    • Outcomes of extended infusion piper-acillin/tazobactam for documented gram-negative infections
    • Patel GW, Patel N, Lat A, et al. Outcomes of extended infusion piper-acillin/tazobactam for documented gram-negative infections. Diagn Microbiol Infect Dis 2009; 64:236-40.
    • (2009) Diagn Microbiol Infect Dis , vol.64 , pp. 236-240
    • Patel, G.W.1    Patel, N.2    Lat, A.3
  • 24
    • 35948970570 scopus 로고    scopus 로고
    • Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial
    • DOI 10.1128/AAC.01318-06
    • Sakka SG, Glauner AK, Bulitta JB, et al. Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial. Antimicrob Agents Chemother 2007; 51:3304-10. (Pubitemid 350067544)
    • (2007) Antimicrobial Agents and Chemotherapy , vol.51 , Issue.9 , pp. 3304-3310
    • Sakka, S.G.1    Glauner, A.K.2    Bulitta, J.B.3    Kinzig-Schippers, M.4    Pfister, W.5    Drusano, G.L.6    Sorgel, F.7
  • 25
    • 60349101365 scopus 로고    scopus 로고
    • Experience with extended-infusion meropenem in the management of ventilator-associated pneumonia due to multidrug-resistant Acinetobacter baumannii
    • Wang D. Experience with extended-infusion meropenem in the management of ventilator-associated pneumonia due to multidrug-resistant Acinetobacter baumannii. Int J Antimicrob Agents 2009; 33:290-1.
    • (2009) Int J Antimicrob Agents , vol.33 , pp. 290-291
    • Wang, D.1
  • 26
    • 84871783450 scopus 로고    scopus 로고
    • A Prospective Observational Study of the Clinical Efficacy and Safety of Bolus versus Extended-Infusions of Meropenem in Critically Ill Patients with Gram-Negative Pneumonia
    • Lee W, Cao JY, Ong S, Chan K, Kwa A. A Prospective Observational Study of the Clinical Efficacy and Safety of Bolus versus Extended-Infusions of Meropenem in Critically Ill Patients with Gram-Negative Pneumonia. Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 2009.
    • (2009) Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
    • Lee, W.1    Cao, J.Y.2    Ong, S.3    Chan, K.4    Kwa, A.5
  • 30
    • 17644430712 scopus 로고    scopus 로고
    • Comparaison de deux schémas d'administration (continu ou discontinu) d'un antibiotique temps-dépendant: La tazocilline
    • DOI 10.1016/S0369-8114(01)00210-3
    • Pedeboscq S, Dubau B, Frappier S, et al. Comparison of 2 administration protocols (continuous or discontinuous) of a time-dependent antibiotic, Tazocin. Pathol Biol (Paris) 2001; 49:540-7. (Pubitemid 32923037)
    • (2001) Pathologie Biologie , vol.49 , Issue.7 , pp. 540-547
    • Pedeboscq, S.1    Dubau, B.2    Frappier, S.3    Hernandez, V.4    Veyssieres, D.5    Winnock, S.6    Pometan, J.P.7
  • 31
    • 79961104396 scopus 로고    scopus 로고
    • The retrospective cohort of extended-infusion piperacillin-tazobactam (receipt) study: A multicenter study
    • Yost RJ, Cappelletty DM. The Retrospective Cohort of Extended-Infusion Piperacillin-Tazobactam (RECEIPT) study: a multicenter study. Pharmacotherapy 2011; 31:767-75.
    • (2011) Pharmacotherapy , vol.31 , pp. 767-775
    • Yost, R.J.1    Cappelletty, D.M.2
  • 32
    • 33748103189 scopus 로고    scopus 로고
    • Cure of persistent, post-appendectomy Klebsiella pneumoniae septicaemia with continuous intravenous administration of meropenem
    • DOI 10.1080/00365540500504125, PII M7013HJ611V65021
    • Falagas ME, Siempos II, Tsakoumis I. Cure of persistent, post-appendectomy Klebsiella pneumoniae septicaemia with continuous intravenous administration of meropenem. Scand J Infect Dis 2006; 38:807-10. (Pubitemid 44304973)
    • (2006) Scandinavian Journal of Infectious Diseases , vol.38 , Issue.9 , pp. 807-810
    • Falagas, M.E.1    Siempos, I.L.2    Tsakoumis, I.3
  • 33
    • 84858629122 scopus 로고    scopus 로고
    • Optimal mero-penem concentrations to treat multi-drug resistant pseudomonas aeru-ginosa septic shock
    • Taccone FS, Cotton F, Roisin S, Vincent JL, Jacobs F. Optimal mero-penem concentrations to treat multi-drug resistant Pseudomonas aeru-ginosa septic shock. Antimicrob Agents Chemother 2012; 56:2129-31.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 2129-2131
    • Taccone, F.S.1    Cotton, F.2    Roisin, S.3    Vincent, J.L.4    Jacobs, F.5
  • 34
    • 79952066185 scopus 로고    scopus 로고
    • Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: Comparison of beta-lactams
    • Paul M, Yahav D, Bivas A, Fraser A, Leibovici L. Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams. Cochrane Database Syst Rev 2010; 11: CD005197.
    • (2010) Cochrane Database Syst Rev , vol.11
    • Paul, M.1    Yahav, D.2    Bivas, A.3    Fraser, A.4    Leibovici, L.5
  • 35
    • 33847727552 scopus 로고    scopus 로고
    • Carbapenems for the treatment of immunocompetent adult patients with nosocomial pneumonia
    • DOI 10.1183/09031936.00080206
    • Siempos II, Vardakas KZ, Manta KG, Falagas ME. Carbapenems for the treatment of immunocompetent adult patients with nosocomial pneumonia. Eur Respir J 2007; 29:548-60. (Pubitemid 46372104)
    • (2007) European Respiratory Journal , vol.29 , Issue.3 , pp. 548-560
    • Siempos, I.I.1    Vardakas, K.Z.2    Manta, K.G.3    Falagas, M.E.4
  • 36
    • 84859845244 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled trials of vancomycin for the treatment of patients with gram-positive infections: Focus on the study design
    • Vardakas KZ, Mavros MN, Roussos N, Falagas ME. Meta-analysis of randomized controlled trials of vancomycin for the treatment of patients with gram-positive infections: focus on the study design. Mayo Clinic Proceedings 2012; 87:349-63.
    • (2012) Mayo Clinic Proceedings , vol.87 , pp. 349-363
    • Vardakas, K.Z.1    Mavros, M.N.2    Roussos, N.3    Falagas, M.E.4
  • 37
    • 0037439449 scopus 로고    scopus 로고
    • Prevention of resistance: A goal for dose selection for antimicrobial agents
    • Drusano GL. Prevention of resistance: a goal for dose selection for antimicrobial agents. Clin Infect Dis 2003; 36:S42-50.
    • (2003) Clin Infect Dis , vol.36
    • Drusano, G.L.1
  • 38
    • 74549138783 scopus 로고    scopus 로고
    • Probability of pharmacodynamic target attainment with standard and prolonged-infusion antibiotic regimens for empiric therapy in adults with hospital-acquired pneumonia
    • Kim A, Kuti JL, Nicolau DP. Probability of pharmacodynamic target attainment with standard and prolonged-infusion antibiotic regimens for empiric therapy in adults with hospital-acquired pneumonia. Clin Ther 2009; 31:2765-78.
    • (2009) Clin Ther , vol.31 , pp. 2765-2778
    • Kim, A.1    Kuti, J.L.2    Nicolau, D.P.3
  • 39
    • 77957892601 scopus 로고    scopus 로고
    • Comparison of 30-min and 3-h infusion regimens for imipenem/cilastatin and for meropenem evaluated by Monte Carlo simulation
    • Lee LS, Kinzig-Schippers M, Nafziger AN, et al. Comparison of 30-min and 3-h infusion regimens for imipenem/cilastatin and for meropenem evaluated by Monte Carlo simulation. Diagn Microbiol Infect Dis 2010; 68:251-8.
    • (2010) Diagn Microbiol Infect Dis , vol.68 , pp. 251-258
    • Lee, L.S.1    Kinzig-Schippers, M.2    Nafziger, A.N.3
  • 40
    • 67449090359 scopus 로고    scopus 로고
    • Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: Intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution
    • Roberts JA, Kirkpatrick CM, Roberts MS, Robertson TA, Dalley AJ, Lipman J. Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. J Antimicrob Chemother 2009; 64:142-50.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 142-150
    • Roberts, J.A.1    Kirkpatrick, C.M.2    Roberts, M.S.3    Robertson, T.A.4    Dalley, A.J.5    Lipman, J.6
  • 41
    • 67650000576 scopus 로고    scopus 로고
    • Comparison of the pharmacodynamics of biapenem in bronchial epithelial lining fluid in healthy volunteers given half-hour and three-hour intravenous infusions
    • Kikuchi E, Kikuchi J, Nasuhara Y, Oizumi S, Ishizaka A, Nishimura M. Comparison of the pharmacodynamics of biapenem in bronchial epithelial lining fluid in healthy volunteers given half-hour and three-hour intravenous infusions. Antimicrob Agents Chemother 2009; 53:2799-803.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2799-2803
    • Kikuchi, E.1    Kikuchi, J.2    Nasuhara, Y.3    Oizumi, S.4    Ishizaka, A.5    Nishimura, M.6
  • 43
    • 80052672933 scopus 로고    scopus 로고
    • Antibiotics in critically ill patients: A systematic review of the pharmacokinetics of beta-lactams
    • Goncalves-Pereira J, Povoa P. Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of beta-lactams. Crit Care 2011; 15:R206.
    • (2011) Crit Care , vol.15
    • Goncalves-Pereira, J.1    Povoa, P.2
  • 45
    • 39049121612 scopus 로고    scopus 로고
    • Carbapenems: A potent class of antibiotics
    • DOI 10.1517/14656566.9.1.23
    • Nicolau DP. Carbapenems: a potent class of antibiotics. Expert Opin Pharmacother 2008; 9:23-37. (Pubitemid 351233746)
    • (2008) Expert Opinion on Pharmacotherapy , vol.9 , Issue.1 , pp. 23-37
    • Nicolau, D.P.1
  • 46
    • 77749345720 scopus 로고    scopus 로고
    • Comparing outcomes of merope-nem administration strategies based on pharmacokinetic and pharmacodynamic principles: A qualitative systematic review
    • Perrott J, Mabasa VH, Ensom MH. Comparing outcomes of merope-nem administration strategies based on pharmacokinetic and pharmacodynamic principles: a qualitative systematic review. Ann Pharmacother 2010; 44:557-64.
    • (2010) Ann Pharmacother , vol.44 , pp. 557-564
    • Perrott, J.1    Mabasa, V.H.2    Ensom, M.H.3
  • 47
    • 34249866197 scopus 로고    scopus 로고
    • Continuous infusion of β-lactam antibiotics in severe infections: A review of its role
    • DOI 10.1016/j.ijantimicag.2007.02.002, PII S0924857907000908
    • Roberts JA, Paratz J, Paratz E, Krueger WA, Lipman J. Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role. Int J Antimicrob Agents 2007; 30:11-8. (Pubitemid 46874893)
    • (2007) International Journal of Antimicrobial Agents , vol.30 , Issue.1 , pp. 11-18
    • Roberts, J.A.1    Paratz, J.2    Paratz, E.3    Krueger, W.A.4    Lipman, J.5
  • 48
    • 25144447426 scopus 로고    scopus 로고
    • Squeezing the antibiotic balloon: The impact of antimicrobial classes on emerging resistance
    • Peterson LR. Squeezing the antibiotic balloon: the impact of antimicrobial classes on emerging resistance. Clin Microbiol Infect 2005; 11 (Suppl 5):4-16. (Pubitemid 41341707)
    • (2005) Clinical Microbiology and Infection, Supplement , vol.11 , Issue.5 , pp. 4-16
    • Peterson, L.R.1
  • 51
    • 4043059435 scopus 로고    scopus 로고
    • Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia? A meta-analysis
    • DOI 10.1016/S1473-3099(04)01108-9, PII S1473309904011089
    • Safdar N, Handelsman J, Maki DG. Does combination antimicrobial therapy reduce mortality in gram-negative bacteraemia? A meta-analysis. Lancet Infect Dis 2004; 4:519-27. (Pubitemid 39077923)
    • (2004) Lancet Infectious Diseases , vol.4 , Issue.8 , pp. 519-527
    • Safdar, N.1    Handelsman, J.2    Maki, D.G.3
  • 52
    • 80055047937 scopus 로고    scopus 로고
    • Impact of definitive therapy with beta-lactam monotherapy or combination with an aminoglycoside or a quinolone for Pseudomonas aeru-ginosa bacteremia
    • Bliziotis IA, Petrosillo N, Michalopoulos A, Samonis G, Falagas ME. Impact of definitive therapy with beta-lactam monotherapy or combination with an aminoglycoside or a quinolone for Pseudomonas aeru-ginosa bacteremia. PLoS One 2011; 6:e26470.
    • (2011) PLoS One , vol.6
    • Bliziotis, I.A.1    Petrosillo, N.2    Michalopoulos, A.3    Samonis, G.4    Falagas, M.E.5
  • 53
    • 0036234739 scopus 로고    scopus 로고
    • Monotherapy or aminoglycoside-containing combinations for empirical antibiotic treatment of febrile neutropenic patients: A meta-analysis
    • DOI 10.1016/S1473-3099(02)00241-4
    • Furno P, Bucaneve G, Del Favero A. Monotherapy or aminoglycoside- containing combinations for empirical antibiotic treatment of febrile neutropenic patients: a meta-analysis. Lancet Infect Dis 2002; 2:231-42. (Pubitemid 34464753)
    • (2002) Lancet Infectious Diseases , vol.2 , Issue.4 , pp. 231-242
    • Furno, P.1    Bucaneve, G.2    Del Favero, A.3
  • 54
    • 1642395344 scopus 로고    scopus 로고
    • Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for sepsis in immunocompetent patients: Systematic review and meta-analysis of randomised trials
    • Paul M, Benuri-Silbiger I, Soares-Weiser K, Leibovici L. Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for sepsis in immunocompetent patients: systematic review and meta-analysis of randomised trials. BMJ 2004; 328:668.
    • (2004) BMJ , vol.328 , pp. 668
    • Paul, M.1    Benuri-Silbiger, I.2    Soares-Weiser, K.3    Leibovici, L.4
  • 55
    • 31544456662 scopus 로고    scopus 로고
    • Empirical antibiotic monotherapy for febrile neutropenia: Systematic review and meta-analysis of randomized controlled trials
    • DOI 10.1093/jac/dki448
    • Paul M, Yahav D, Fraser A, Leibovici L. Empirical antibiotic mono-therapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother 2006; 57:176-89. (Pubitemid 43160156)
    • (2006) Journal of Antimicrobial Chemotherapy , vol.57 , Issue.2 , pp. 176-189
    • Paul, M.1    Yahav, D.2    Fraser, A.3    Leibovici, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.