Laminin network formation studied by reconstitution of ternary nodes in solution

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44270-44277

  Purvis, Alan ^a   Hohenester, Erhard ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BASEMENT MEMBRANE; BINARY COMPLEXES; CHAIN FRAGMENTS; EPIDERMAL GROWTH; HETEROTRIMERS; KEY PROCESS; LAMININ; N-TERMINALS; NETWORK FORMATION; NETWORK NODE; STRUCTURE-FUNCTION STUDIES; TERNARY COMPLEX;

STOICHIOMETRY;

POLYMERIZATION;

CELL PROTEIN; LAMININ; LAMININ ALPHA1; LAMININ ALPHA2; LAMININ ALPHA5; LAMININ BETA1; LAMININ GAMMA1; RECOMBINANT PROTEIN; SERINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CHIMERA; COMPLEX FORMATION; HUMAN; HUMAN CELL; ION EXCLUSION CHROMATOGRAPHY; LIGHT SCATTERING; MEMBRANE FORMATION; MOLECULAR INTERACTION; MOLECULAR WEIGHT; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE;

ANIMALS; BASEMENT MEMBRANE; HEK293 CELLS; HUMANS; KINETICS; LAMININ; MICE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY;

EID: 84871801643     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.418426     Document Type: Article

References (23)

1. Yurchenco, P. D. (2011) Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harb. Perspect. Biol. 3, a004911
2. Miner, J. H., and Yurchenco, P. D. (2004) Laminin functions in tissue morphogenesis. Annu. Rev. Cell Dev. Biol. 20, 255-284 (Pubitemid 39488639)
3. Aumailley, M., Bruckner-Tuderman, L., Carter, W. G., Deutzmann, R., Edgar, D., Ekblom, P., Engel, J., Engvall, E., Hohenester, E., Jones, J. C., Kleinman, H. K., Marinkovich, M. P., Martin, G. R., Mayer, U., Meneguzzi, G., Miner, J. H., Miyazaki, K., Patarroyo, M., Paulsson, M., Quaranta, V., Sanes, J. R., Sasaki, T., Sekiguchi, K., Sorokin, L. M., Talts, J. F., Tryggvason, K., Uitto, J., Virtanen, I., von der Mark, K., Wewer, U. M., Yamada, Y., and Yurchenco, P. D. (2005) A simplified laminin nomenclature. Matrix Biol. 24, 326-332 (Pubitemid 41021635)
4. Beck, K., Hunter, I., and Engel, J. (1990) Structure and function of laminin: anatomy of a multidomain glycoprotein. FASEB J. 4, 148-160
5. Bruch, M., Landwehr, R., and Engel, J. (1989) Dissection of laminin by cathepsinGinto its long-arm and short-arm structures and localization of regions involved in calcium-dependent stabilization and self-association. Eur. J. Biochem. 185, 271-279 (Pubitemid 19276629)
6. Cheng, Y. S., Champliaud, M. F., Burgeson, R. E., Marinkovich, M. P., and Yurchenco, P. D. (1997) Self-assembly of laminin isoforms. J. Biol. Chem. 272, 31525-31532 (Pubitemid 28013294)
7. McKee, K. K., Harrison, D., Capizzi, S., and Yurchenco, P. D. (2007) Role of laminin terminal globular domains in basement membrane assembly. J. Biol. Chem. 282, 21437-21447 (Pubitemid 47099937)
8. 2+ binding in the self-aggregation of laminin-nidogen complexes. J. Biol. Chem. 263, 5425-5430
9. Schittny, J. C., and Yurchenco, P. D. (1990) Terminal short arm domains of basement membrane laminin are critical for its self-assembly. J. Cell Biol. 110, 825-832
10. Yurchenco, P. D., and Cheng, Y. S. (1993) Self-assembly and calcium-binding sites in laminin. A three-arm interaction model. J. Biol. Chem. 268, 17286-17299 (Pubitemid 23236966)
11. Yurchenco, P. D., Cheng, Y. S., and Colognato, H. (1992) Laminin forms an independent network in basement membranes. J. Cell Biol. 117, 1119-1133
12. Yurchenco, P. D., Tsilibary, E. C., Charonis, A. S., and Furthmayr, H. (1985) Laminin polymerization in vitro. Evidence for a two-step assembly with domain specificity. J. Biol. Chem. 260, 7636-7644 (Pubitemid 15063049)
13. Odenthal, U., Haehn, S., Tunggal, P., Merkl, B., Schomburg, D., Frie, C., Paulsson, M., and Smyth, N. (2004) Molecular analysis of laminin N-terminal domains mediating self-interactions. J. Biol. Chem. 279, 44504-44512 (Pubitemid 39430857)
14. Carafoli, F., Hussain, S. A., and Hohenester, E. (2012) Crystal structures of the network-forming short-arm tips of the laminin β1 and γ1 chains. PLoS ONE 7, e42473
15. Hussain, S. A., Carafoli, F., and Hohenester, E. (2011) Determinants of laminin polymerization revealed by the structure of the α5 chain aminoterminal region. EMBO Rep. 12, 276-282
16. Kohfeldt, E., Maurer, P., Vannahme, C., and Timpl, R. (1997) Properties of the extracellular calcium binding module of the proteoglycan testican. FEBS Lett. 414, 557-561 (Pubitemid 27390667)
17. Wen, J., Arakawa, T., and Philo, J. S. (1996) Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions. Anal. Biochem. 240, 155-166 (Pubitemid 26304259)
18. Garbe, J. H., Göhring, W., Mann, K., Timpl, R., and Sasaki, T. (2002) Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin α3B and α5 chains. Biochem. J. 362, 213-221 (Pubitemid 34174478)
19. Lehnhardt, A., Lama, A., Amann, K., Matejas, V., Zenker, M., and Kemper, M. J. (2012) Pierson syndrome in an adolescent girl with nephrotic range proteinuria but a normal GFR. Pediatr. Nephrol. 27, 865-868
20. Matejas, V., Hinkes, B., Alkandari, F., Al-Gazali, L., Annexstad, E., Aytac, M. B., Barrow, M., Bláhová, K., Bockenhauer, D., Cheong, H. I., Maruniak-Chudek, I., Cochat, P., Dötsch, J., Gajjar, P., Hennekam, R. C., Janssen, F., Kagan, M., Kariminejad, A., Kemper, M. J., Koenig, J., Kogan, J., Kroes, H. Y., Kuwertz-Bröking, E., Lewanda, A. F., Medeira, A., Muscheites, J., Niaudet, P., Pierson, M., Saggar, A., Seaver, L., Suri, M., Tsygin, A., Wühl, E., Zurowska, A., Uebe, S., Hildebrandt, F., Antignac, C., and Zenker, M. (2010) Mutations in the human laminin β2 (LAMB2) gene and the associated phenotypic spectrum. Hum. Mutat. 31, 992-1002
21. Oosawa, F., and Kasai, M. (1962) A theory of linear and helical aggregations of macromolecules. J. Mol. Biol. 4, 10-21
22. Stevens, F. J. (1989) Analysis of protein-protein interaction by simulation of small-zone size exclusion chromatography. Stochastic formulation of kinetic rate contributions to observed high-performance liquid chromatography elution characteristics. Biophys. J. 55, 1155-1167
23. Chen, Y. M., Kikkawa, Y., and Miner, J. H. (2011) A missense LAMB2 mutation causes congenital nephrotic syndrome by impairing laminin secretion. J. Am. Soc. Nephrol. 22, 849-858