Behavioral Abnormalities Observed in Zfhx2-Deficient Mice

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Komine, Yuriko ^a   Takao, Keizo ^b,c,d,e   Miyakawa, Tsuyoshi ^b,c,d,e   Yamamori, Tetsuo ^a  

^a NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d FUJITA HEALTH UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZFHX2 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; DEPRESSION; EMBRYO; EMOTION; FORCED SWIMMING TEST; GENE; HOMOZYGOSITY; HYPERACTIVITY; LOCOMOTION; MAZE TEST; MONOAMINE NERVE CELL; MOUSE; NONHUMAN; OPEN FIELD TEST; REFERENCE MEMORY; SPATIAL MEMORY; ZFHX2 GENE;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; DEPRESSION; HOMEODOMAIN PROTEINS; HYPERKINESIS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; PHENOTYPE; RNA, MESSENGER; TRANSCRIPTION FACTORS;

MUS;

EID: 84871793550     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053114     Document Type: Article

References (21)

1. Komine Y, Nakamura K, Katsuki M, Yamamori T, (2006) Novel transcription factor zfh-5 is negatively regulated by its own antisense RNA in mouse brain. Mol Cell Neurosci 31: 273-283.
2. Holland P, Booth H, Bruford E, (2007) Classification and nomenclature of all human homeobox genes. BMC Biol 5: 47.
3. Jung C, Kim H, Kawaguchi M, Khanna K, Hida H, et al. (2005) Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development 132: 5137-5145.
4. Sun X, Frierson H, Chen C, Li C, Ran Q, et al. (2005) Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer. Nat Genet 37: 407-412.
5. Kim C, Song J, Cho Y, Cao Z, Lee Y, et al. (2008) Down-regulation of ATBF1 is a major inactivating mechanism in hepatocellular carcinoma. Histopathology 52: 552-559.
6. McMullan T, Crolla J, Gregory S, Carter N, Cooper R, et al. (2002) A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation. Hum Genet 110: 244-250.
7. Takao K, Yamasaki N, Miyakawa T, (2007) Impact of brain-behavior phenotypying of genetically-engineered mice on research of neuropsychiatric disorders. Neurosci Res 58: 124-132.
8. Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, et al. (2008) Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain 1: 6.
9. Zhuang X, Oosting R, Jones S, Gainetdinov R, Miller G, et al. (2001) Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proc Natl Acad Sci U S A 98: 1982-1987.
10. Miyakawa T, Leiter L, Gerber D, Gainetdinov R, Sotnikova T, et al. (2003) Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia. Proc Natl Acad Sci U S A 100: 8987-8992.
11. Prickaerts J, Moechars D, Cryns K, Lenaerts I, van Craenendonck H, et al. (2006) Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. J Neurosci 26: 9022-9029.
12. Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, et al. (2007) Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci U S A 104: 14501-14506.
13. Cox M, Tucker A, Tang J, Talbot K, Richer D, et al. (2009) Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background. Genes Brain Behav 8: 390-397.
14. Porsolt R, Le Pichon M, Jalfre M, (1977) Depression: a new animal model sensitive to antidepressant treatments. Nature 266: 730-732.
15. Crowley J, Jones M, O'Leary O, Lucki I, (2004) Automated tests for measuring the effects of antidepressants in mice. Pharmacol Biochem Behav 78: 269-274.
16. Carola V, D'Olimpio F, Brunamonti E, Mangia F, Renzi P, (2002) Evaluation of the elevated plus-maze and open-field tests for the assessment of anxiety-related behaviour in inbred mice. Behav Brain Res 134: 49-57.
17. Ramos A, (2008) Animal models of anxiety: do I need multiple tests? Trends Pharmacol Sci 29: 493-498.
18. Schaeren-Wiemers N, Gerfin-Moser A, (1993) A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100: 431-440.
19. Takao K, Tanda K, Nakamura K, Kasahara J, Nakao K, et al. (2010) Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice. PLoS One 5: e9460.
20. Yao I, Takao K, Miyakawa T, Ito S, Setou M, (2011) Synaptic E3 ligase SCRAPPER in contextual fear conditioning: extensive behavioral phenotyping of Scrapper heterozygote and overexpressing mutant mice. PLoS One 6: e17317.
21. Takao K, Miyakawa T (2006) Light/dark transition test for mice. J Vis Exp: 104.