Effects of nutritional enrichment on the production of acetone-butanol-ethanol (ABE) by Clostridium acetobutylicum

Journal of Microbiology

Volumn 50, Issue 6, 2012, Pages 1063-1066

  Choi, Sung Jun ^a,b   Lee, Joungmin ^a   Jang, Yu Sin ^a   Park, Jin Hwan ^a   Lee, Sang Yup ^a   Kim, In Ho ^b  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

ABE; cell density; Clostridium acetobutylicum; phase transition; productivity

Indexed keywords

ACETONE; ALCOHOL; BIOFUEL; BUTANOL;

ARTICLE; CLOSTRIDIUM ACETOBUTYLICUM; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

ACETONE; BIOFUELS; BUTANOLS; CLOSTRIDIUM ACETOBUTYLICUM; ETHANOL; FERMENTATION;

CLOSTRIDIUM ACETOBUTYLICUM;

EID: 84871791101     PISSN: 12258873     EISSN: 19763794     Source Type: Journal    
DOI: 10.1007/s12275-012-2373-1     Document Type: Article

References (21)

1. Bahl, H., Andersch, W., and Gottschalk, G. 1982. Continuous production of acetone and butanol by Clostridium acetobutylicum in a two-stage phosphate limited chemostat. Appl. Microbiol. Biotechnol. 15, 201-205.
2. Bahl, H., Gottwald, M., Kuhn, A., Rale, V., Andersch, W., and Gottschalk, G. 1986. Nutritional factors affecting the ratio of solvents produced by Clostridium acetobutylicum. Appl. Environ. Microbiol. 52, 169-172.
3. Bryant, D. L. and Blaschek, H. P. 1988. Buffering as a means for increasing growth and butanol production by Clostridium acetobutylicum. J. Ind. Microbiol. Biotechnol. 3, 49-55.
4. Durre, P. 2007. Biobutanol: an attractive biofuel. Biotechnol. J. 2, 1525-1534.
5. Ezeji, T. C., Qureshi, N., and Blaschek, H. P. 2007. Bioproduction of butanol from biomass: from genes to bioreactors. Curr. Opin. Biotechnol. 18, 220-227.
6. Gu, Y., Jiang, Y., Wu, H., Liu, X., Li, Z., Li, J., Xiao, H., Shen, Z., Dong, H., Yang, Y., andet al. 2011. Economical challenges to microbial producers of butanol: feedstock, butanol ratio and titer. Biotechnol. J. 6, 1348-1357.
7. Jang, Y. S., Kim, B., Shin, J. H., Choi, Y. J., Choi, S., Song, C. W., Lee, J., Park, H. G., and Lee, S. Y. 2012a. Bio-based production of C2-C6 platform chemicals. Biotechnol. Bioeng. 109, 2437-2459.
8. Jang, Y. S., Lee, J., Malaviya, A., Seung, D. Y., Cho, J. H., and Lee, S. Y. 2012b. Butanol production from renewable biomass: rediscovery of metabolic pathways and metabolic engineering. Biotechnol. J. 7, 186-198.
9. Jones, D. T. and Woods, D. R. 1986. Acetone-butanol fermentation revisited. Microbiol. Rev. 50, 484-524.
10. Kell, D. B., Peck, M. W., Rodger, G., and Morris, J. G. 1981. On the permeability to weak acids and bases of the cytoplasmic membrane of Clostridium pasteurianum. Biochem. Biophys. Res. Commun. 99, 81-88.
11. Lee, J. Y., Jang, Y. S., Lee, J., Papoutsakis, E. T., and Lee, S. Y. 2009. Metabolic engineering of Clostridium acetobutylicum M5 for highly selective butanol production. Biotechnol. J. 4, 1432-1440.
12. Lee, S. Y., Park, J. H., Jang, S. H., Nielsen, L. K., Kim, J., and Jung, K. S. 2008. Fermentative butanol production by Clostridia. Biotechnol. Bioeng. 101, 209-228.
13. Malaviya, A., Jang, Y. S., and Lee, S. Y. 2012. Continuous butanol production with reduced byproducts formation from glycerol by a hyper producing mutant of Clostridium pasteurianum. Appl. Microbiol. Biotechnol. 93, 1485-1494.
14. Monot, F., Martin, J. R., Petitdemange, H., and Gay, R. 1982. Acetone and butanol production by Clostridium acetobutylicum in a synthetic medium. Appl. Environ. Microbiol. 44, 1318-1324.
15. Nicolaou, S. A., Gaida, S. M., and Papoutsakis, E. T. 2010. A comparative view of metabolite and substrate stress and tolerance in microbial bioprocessing: From biofuels and chemicals, to biocatalysis and bioremediation. Metab. Eng. 12, 307-331.
16. Papoutsakis, E. T. 2008. Engineering solventogenic clostridia. Curr. Opin. Biotechnol. 19, 420-429.
17. Paredes, C. J., Alsaker, K. V., and Papoutsakis, E. T. 2005. A comparative genomic view of clostridial sporulation and physiology. Nat. Rev. Microbiol. 3, 969-978.
18. Roos, J. W., McLaughlin, J. K., and Papoutsakis, E. T. 1985. The effect of pH on nitrogen supply, cell lysis, and solvent production in fermentations of Clostridium acetobutylicum. Biotechnol. Bioeng. 27, 681-694.
19. Sillers, R., Chow, A., Tracy, B., and Papoutsakis, E. T. 2008. Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance. Metab. Eng. 10, 321-332.
20. Tashiro, Y., Takeda, K., Kobayashi, G., and Sonomoto, K. 2005. High production of acetone-butanol-ethanol with high cell density culture by cell-recycling and bleeding. J. Biotechnol. 120, 197-206.
21. Zhao, Y., Tomas, C. A., Rudolph, F. B., Papoutsakis, E. T., and Bennett, G. N. 2005. Intracellular butyryl phosphate and acetyl phosphate concentrations in Clostridium acetobutylicum and their implications for solvent formation. Appl. Environ. Microbiol. 71, 530-537.