Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1

BMC Biochemistry

Volumn 13, Issue 1, 2012, Pages

  Grönholm, Juha ^a   Vanhatupa, Sari ^a   Ungureanu, Daniela ^a   Väliaho, Jouni ^a   Laitinen, Tuomo ^b   Valjakka, Jarkko ^a   Silvennoinen, Olli ^a,c  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Interferon; Signal transducers and activators of transcription (STATs); Signal transduction; Sumoylation; Transcription factors

Indexed keywords

GAMMA INTERFERON; HISTONE H4; STAT1 PROTEIN; DNA; HISTONE; PROTEINASE; RECOMBINANT PROTEIN; SENP1 PROTEIN, HUMAN; STAT1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; HISTONE ACETYLATION; HUMAN; HUMAN CELL; MOLECULAR MODEL; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; STRUCTURE ACTIVITY RELATION; SUMOYLATION; ACETYLATION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; BIOSYNTHESIS; CHEMISTRY; CHLOROCEBUS AETHIOPS; CHROMATIN IMMUNOPRECIPITATION; COS 1 CELL LINE; DIMERIZATION; GENETICS; HELA CELL LINE; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ACETYLATION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; CHROMATIN IMMUNOPRECIPITATION; COS CELLS; DIMERIZATION; DNA; ENDOPEPTIDASES; HELA CELLS; HISTONES; HUMANS; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STAT1 TRANSCRIPTION FACTOR; SUMOYLATION;

EID: 84871785836     PISSN: None     EISSN: 14712091     Source Type: Journal    
DOI: 10.1186/1471-2091-13-20     Document Type: Article

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