Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: The in vitro osteoclast differentiation in arthritis study

Arthritis and Rheumatism

Volumn 65, Issue 1, 2013, Pages 148-158

  Durand, Marianne ^a   Komarova, Svetlana V ^b   Bhargava, Ajay ^c   Trebec Reynolds, Diana P ^c   Li, Keying ^c   Fiorino, Cara ^c   Maria, Osama ^b   Nabavi, Noushin ^c   Manolson, Morris F ^c   Harrison, Rene E ^c   Dixon, S Jeffrey ^d   Sims, Stephen M ^d   Mizianty, Marcin J ^e   Kurgan, Lukasz ^e   Haroun, Sonia ^a   Boire, Gilles ^a   De Fatima Lucena Fernandes, Maria ^a   De Brum Fernandes, Artur J ^a  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d WESTERN UNIVERSITY   (Canada)

^e UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CD14 ANTIGEN; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ADULT; AGED; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; ASSAY; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MONOCYTE; OSTEOARTHRITIS; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPOROSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGED; AGED, 80 AND OVER; ANTIGENS, CD14; APOPTOSIS; BONE RESORPTION; CELL CULTURE TECHNIQUES; CYTOKINES; FEMALE; HUMANS; IMMUNOBLOTTING; MALE; MIDDLE AGED; MONOCYTES; OSTEOARTHRITIS; OSTEOCLASTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84871785730     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37722     Document Type: Article

References (31)

1. Reichenbach S, Guermazi A, Niu J, Neogi T, Hunter DJ, Roemer FW, et al. Prevalence of bone attrition on knee radiographs and MRI in a community-based cohort. Osteoarthritis Cartilage 2008; 16: 1005-10.
2. Carlson CS, Loeser RF, Jayo MJ, Weaver DS, Adams MR, Jerome CP,. Osteoarthritis in cynomolgus macaques: a primate model of naturally occurring disease. J Orthop Res 1994; 12: 331-9.
3. Hilal G, Martel-Pelletier J, Pelletier JP, Ranger P, Lajeunesse D,. Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosis. Arthritis Rheum 1998; 41: 891-9.
4. Bettica P, Cline G, Hart DJ, Meyer J, Spector TD,. Evidence for increased bone resorption in patients with progressive knee osteoarthritis: longitudinal results from the Chingford study. Arthritis Rheum 2002; 46: 3178-84.
5. Carbone LD, Nevitt MC, Wildy K, Barrow KD, Harris F, Felson D, et al, for the Health, Aging and Body Composition Study. The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum 2004; 50: 3516-25.
6. Danks L, Sabokbar A, Gundle R, Athanasou NA,. Synovial macrophage-osteoclast differentiation in inflammatory arthritis. Ann Rheum Dis 2002; 61: 916-21.
7. Suzuki Y, Tsutsumi Y, Nakagawa M, Suzuki H, Matsushita K, Beppu M, et al. Osteoclast-like cells in an in vitro model of bone destruction by rheumatoid synovium. Rheumatology (Oxford) 2001; 40: 673-82.
8. Hayami T, Pickarski M, Wesolowski GA, Mclane J, Bone A, Destefano J, et al. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum 2004; 50: 1193-206.
9. Strassle BW, Mark L, Leventhal L, Piesla MJ, Jian Li X, Kennedy JD, et al. Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. Osteoarthritis Cartilage 2010; 18: 1319-28.
10. Durand M, Boire G, Komarova SV, Dixon SJ, Sims SM, Harrison RE, et al. The increased in vitro osteoclastogenesis in patients with rheumatoid arthritis is due to increased percentage of precursors and decreased apoptosis-the In Vitro Osteoclast Differentiation in Arthritis (IODA) study. Bone 2011; 48: 588-96.
11. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29: 1039-49.
12. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW,. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988; 15: 1833-40.
13. Kellgren JH, Lawrence JS,. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957; 16: 494-502.
14. Trebec DP, Chandra D, Gramoun A, Li K, Heersche JN, Manolson MF,. Increased expression of activating factors in large osteoclasts could explain their excessive activity in osteolytic diseases. J Cell Biochem 2007; 101: 205-20.
15. Manolson MF, Yu H, Chen W, Yao Y, Li K, Lees RL, et al. The a3 isoform of the 100-kDa V-ATPase subunit is highly but differentially expressed in large (≥10 nuclei) and small (≤5 nuclei) osteoclasts. J Biol Chem 2003; 278: 49271-8.
16. Hall M, Eibe F, Holmes G, Pfahringer B, Reutemann P, Witten IH,. The WEKA data mining software: an update. SIGKDD Explorations 2009; 11: 10-8.
17. Le Cessie S, van Houwelingen J,. Ridge estimators in logistic regression. Appl Statist 1992; 41: 191-201.
18. Baldi P, Brunak S, Chauvin Y, Andersen CA, Nielsen H,. Assessing the accuracy of prediction algorithms for classification: an overview. Bioinformatics 2000; 16: 412-24.
19. Oh SR, Sul OJ, Kim YY, Kim HJ, Yu R, Suh JH, et al. Saturated fatty acids enhance osteoclast survival. J Lipid Res 2010; 51: 892-9.
20. Lohmander LS, Gerhardsson de Verdier M, Rollof J, Nilsson PM, Engstrom G,. Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study. Ann Rheum Dis 2009; 68: 490-6.
21. Davies-Tuck ML, Wluka AE, Forbes A, Wang Y, English DR, Giles GG, et al. Smoking is associated with increased cartilage loss and persistence of bone marrow lesions over 2 years in community-based individuals. Rheumatology (Oxford) 2009; 48: 1227-31.
22. Juhakoski R, Heliovaara M, Impivaara O, Kroger H, Knekt P, Lauren H, et al. Risk factors for the development of hip osteoarthritis: a population-based prospective study. Rheumatology (Oxford) 2009; 48: 83-7.
23. Looker AC, Orwoll ES, Johnston CC Jr, Lindsay RL, Wahner HW, Dunn WL, et al. Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res 1997; 12: 1761-8.
24. Xu LX, Kukita T, Nakano Y, Yu H, Hotokebuchi T, Kuratani T, et al. Osteoclasts in normal and adjuvant arthritis bone tissues express the mRNA for both type I and II interleukin-1 receptors. Lab Invest 1996; 75: 677-87.
25. Trebec-Reynolds DP, Voronov I, Heersche JN, Manolson MF,. IL-1α and IL-1β have different effects on formation and activity of large osteoclasts. J Cell Biochem 2010; 109: 975-82.
26. Jules J, Zhang P, Ashley JW, Wei S, Shi Z, Liu J, et al. Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis. J Biol Chem 2012; 287: 15728-38.
27. Smith AJ, Keen LJ, Billingham MJ, Perry MJ, Elson CJ, Kirwan JR, et al. Extended haplotypes and linkage disequilibrium in the IL1R1-IL1A-IL1B-IL1RN gene cluster: association with knee osteoarthritis. Genes Immun 2004; 5: 451-60.
28. high osteoclast precursors in tumor necrosis factor α-transgenic mice. Arthritis Rheum 2004; 50: 265-76.
29. Mensah KA, Mathian A, Ma L, Xing L, Ritchlin CT, Schwarz EM,. Mediation of nonerosive arthritis in a mouse model of lupus by interferon-α- stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis. Arthritis Rheum 2010; 62: 1127-37.
30. Schwarz EM, Proulx ST, Ritchlin CT, Boyce BF, Xing L,. The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis. Adv Exp Med Biol 2010; 658: 1-10.
31. Guo R, Zhou Q, Proulx ST, Wood R, Ji RC, Ritchlin CT, et al. Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis Rheum 2009; 60: 2666-76.