A novel amino acid substitution of integrin αiIb in Glanzmann thrombasthenia confirms that the N-terminal region of the receptor plays a role in maintaining β-propeller structure

Platelets

Volumn 24, Issue 1, 2013, Pages 77-80

  Pillois, Xavier ^a   Fiore, Mathieu ^a   Heilig, Roland ^b   Pico, Marta ^c   Nurden, Alan T ^a  

^a Ctr Geriatrie Ctr Hosp Univ B   (France)

^b CENTRE NATIONAL DE SÉQUENÇAGE   (France)

^c Hospital Val d'Hebron   (Spain)

Author keywords

IIb 3; Glanzmann thrombasthenia; ITGA2B; Mutation analysis

Indexed keywords

ALPHA2B INTEGRIN; GLYCOPROTEIN; RISTOCETIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BETA PROPELLER STRUCTURE; BLEEDING; BLOOD EXAMINATION; EPISTAXIS; ERYTHROCYTE CONCENTRATE; FAMILY STUDY; FEMALE; GENE; GENE DELETION; GENE MUTATION; GENETIC SCREENING; GLANZMANN DISEASE; HETEROZYGOSITY; HOSPITAL READMISSION; HUMAN; ITGA2B GENE; MALE; MENARCHE; PERIODONTAL DISEASE; POSTPARTUM HEMORRHAGE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; THROMBOCYTE AGGREGATION; THROMBOCYTE TRANSFUSION;

AMINO ACID SUBSTITUTION; BASE SEQUENCE; HUMANS; INTEGRIN BETA3; MUTATION; PLATELET MEMBRANE GLYCOPROTEIN IIB; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; THROMBASTHENIA;

EID: 84871780276     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2012.665278     Document Type: Article

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