Silencing of STIM1 attenuates hypoxia-induced PASMCs proliferation via inhibition of the SOC/Ca2+/NFAT pathway

Respiratory Research

Volumn 14, Issue 1, 2013, Pages

  Hou, Xianhua ^a,b   Chen, Jian ^a,b   Luo, Yongjun ^a,b   Liu, Fuyu ^a,b   Xu, Gang ^a,b   Gao, Yuqi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Key Laboratory of High Altitude Physiology and High Altitude Diseases   (China)

Author keywords

Cell proliferation; Hypoxia; Pulmonary hypertension; RNA interference; Stromal interaction molecule 1

Indexed keywords

CALCIUM CHANNEL; MESSENGER RNA; SMOOTH MUSCLE ACTIN; STORE OPERATED CALCIUM CHANNEL; STROMAL INTERACTION MOLECULE 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT3; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; STIM1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTERIAL WALL THICKNESS; ARTICLE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; GENE SILENCING; HYPOXIA; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; LUNG ARTERY PRESSURE; LUNG SMOOTH MUSCLE CELL; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PULMONARY ARTERY; PULMONARY HYPERTENSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SMOOTH MUSCLE CELL; UPREGULATION; VASCULAR REMODELING; WESTERN BLOTTING; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CALCIUM SIGNALING; CELL CULTURE; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WISTAR RAT; DRUG ANTAGONISM;

ANIMALS; ANOXIA; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL PROLIFERATION; CELLS, CULTURED; GENE SILENCING; MALE; MEMBRANE GLYCOPROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NFATC TRANSCRIPTION FACTORS; PULMONARY ARTERY; RATS; RATS, WISTAR;

EID: 84871775342     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-14-2     Document Type: Article

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