Non-ionic Gd-based MRI contrast agents are optimal for encapsulation into phosphatidyldiglycerol-based thermosensitive liposomes

Journal of Controlled Release

Volumn 166, Issue 1, 2013, Pages 22-29

  Hossann, Martin ^a,b   Wang, Tungte ^a,b   Syunyaeva, Zulfiya ^a   Wiggenhorn, Michael ^c   Zengerle, Anja ^a   Issels, Rolf D ^a,b   Reiser, Maximilian ^a   Lindner, Lars H ^a,b   Peller, Michael ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c Coriolis PharmaService GmbH ^*  (Germany)

Author keywords

Gd based contrast agent; Hyperthermia; Phosphatidyloligoglycerol; Proton magnetic resonance; Thermosensitive liposomes

Indexed keywords

CONTRAST AGENT; GD-DOTA; GD-DTPA; HIGH CONCENTRATION; HYPERTHERMIA; INTERVENTIONAL; LONGITUDINAL RELAXATION TIME; MONO-DISPERSED; MRI CONTRAST AGENTS; NONIONIC; OSMOLALITY; PHOSPHATIDYLOLIGOGLYCEROL; PHOSPHOCHOLINE; RELAXIVITY; SERUM PROTEINS; SHELF LIFE; SOLID TUMORS; TEMPERATURE RANGE; THERMOSENSITIVE LIPOSOMES; THERMOTHERAPIES; VESICLE SIZE;

MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE; OPTIMIZATION; PHOSPHOLIPIDS; SIGNAL SYSTEMS; ZETA POTENTIAL;

GADOLINIUM;

DIPALMITOYLPHOSPHATIDYLGLYCEROL; DISTEAROYLPHOSPHATIDIC ACID; GADOBENATE DIMEGLUMINE; GADOBUTROL; GADODIAMIDE; GADOLINIUM PENTETATE MEGLUMINE; GADOTERATE MEGLUMINE; GADOTERIDOL; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G; LIPOSOME; MAGNOGRAF; NONIONIC CONTRAST MEDIUM; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; PHOSPHATIDYLGLYCEROL; THERMOSENSITIVE LIPOSOME; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DIFFUSION; DISPERSION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; ENCAPSULATION; FEASIBILITY STUDY; HEAT; LIPID BILAYER; LIPID HYDROLYSIS; MEMBRANE PERMEABILITY; OSMOLALITY; PHASE TRANSITION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STORAGE TEMPERATURE; TEMPERATURE SENSITIVITY;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; CONTRAST MEDIA; DRUG CARRIERS; DRUG COMPOUNDING; GADOLINIUM DTPA; LIPOSOMES; MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; SURFACE PROPERTIES; TRANSITION TEMPERATURE;

EID: 84871766347     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.12.003     Document Type: Article

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