A randomized, double-blinded placebo-controlled clinical trial of the routine use of preoperative antibiotic prophylaxis in modified radical mastectomy

World Journal of Surgery

Volumn 37, Issue 1, 2013, Pages 59-66

  Cabaluna, Nelson D ^a   Uy, Gemma B ^a   Galicia, Rommel M ^a   Cortez, Shalimar C ^a   Yray, Marc Denver S ^a   Buckley, Brian S ^a  

^a UNIVERSITY OF THE PHILIPPINES MANILA   (Philippines)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MASTECTOMY; MIDDLE AGED; PREOPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL; SURGICAL INFECTION;

ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MASTECTOMY, MODIFIED RADICAL; MIDDLE AGED; PREOPERATIVE CARE; SURGICAL WOUND INFECTION;

EID: 84871763567     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-012-1816-5     Document Type: Article

References (20)

1. Brennan TA, Leape LL, Laird NM et al (1991) Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard medical practice study I. N Engl J Med 324:370-376
2. Kirkland KB, Briggs JP, Trivette SL et al (1999) The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 20:725-730
3. Bunn F, Jones DJ, Bell-Syer S (2012) Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery. Cochrane Database of Systematic Rev; 1, CD005360. doi: 10.1002/14651858.CD005360.pub3
4. Mallari-Cutungal MG, Codamos LJ, Coronel RF (1999) Antibiotic prophylaxis in elective breast surgery: a meta-analysis of randomized placebo-controlled trials. Philipp J Microbiol Infect Dis 28:154-158
5. Bold RJ, Mansfield PF, Berger DH et al (1998) Prospective randomized, double-blind study of prophylactic antibiotics in axillary lymph node dissection. Am J Surg 176:239-243
6. Gupta RM, Sinnet D, Carpenter R et al (2000) Antibiotic prophylaxis for post-operative infection in clean elective breast surgery. Eur J Surg Oncol 26:363-366
7. Platt R, Zaleznik DF, Hopkins CC et al (1990) Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery. N Engl J Med 322:153-160
8. Philippine College of Surgeons (2001) Evidence-based clinical practice guidelines for antibiotic prophylaxis in elective surgical procedures. PCS, Manila
9. Scottish Intercollegiate Guidelines Network (2008) Antibiotic prophylaxis in surgery. A national clinical guideline. SIGN, Edinburgh
10. National Collaborating Centre for Women's Children's health/national institute for health and clinical excellence (2008) Surgical site infection: prevention and treatment of surgical site infection. NICE, London
11. Western Australia Department of Health (2009) CPI Guide to surgical site infection prevention. Government of Western Australia Department of Health, Perth
12. Hong Kong Centre for Health Protection (2009) Recommendations on Prevention of Surgical Site Infection. Centre for Health Protection, Department of Health, Hong Kong
13. Horan TC, Gaynes RP, Martone WJ et al (1992) CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13:606-608
14. Chow LW, Yuen KY, Woo PC et al (2000) Clarythromycin attenuates mastectomy-induced acute inflammatory response. Clin Diagn Lab Immunol 7:925-931
15. Wagman LD, Tegtmeier B, Beatty JD et al (1990) A prospective, randomised double-blind study of the use of antibiotics at the time of mastectomy. Surg Gynecol Obstet 170:12-16
16. Culver DH, Horan TC, Gaynes RP et al (1991) Surgical wound infection rates by wound class, operative procedure, and patient risk index. National nosocomial infections surveillance system. Am J Med 91:152S-157S
17. Smyth ET, McIlvenny G, Enstone JE et al (2008) Four country healthcare associated infection prevalence survey 2006: overview of the results. J Hosp Infect 69:230-248
18. Hall JC, Willsher PC, Hall JL (2006) Randomized clinical trial of single dose antibiotic prophylaxis for non-reconstructive breast surgery. Br J Surg 93:1342-1346
19. Amland PF, Andenaes K, Samdal F et al (1995) A prospective double-blind, placebo-controlled trial of a single dose of azithromycin on postoperative wound infections in plastic surgery. Plast Reconstr Surg 96:1378-1383
20. Paajanen H, Hermunen H (2009) Does preoperative core needle biopsy increase surgical site infections in breast cancer surgery? Randomized study of antibiotic prophylaxis. Surg Infect 10:317-321