Antibiotic prophylaxis for post-operative wound infection in clean elective breast surgery

European Journal of Surgical Oncology

Volumn 26, Issue 4, 2000, Pages 363-366

  Gupta, R ^a   Sinnett, D ^b   Carpenter, R ^c   Preece, P E ^d   Royle, G T ^a  

^a ROYAL SOUTH HANTS HOSPITAL   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Antibiotic prophylaxis; Post operative infections

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT;

ADULT; AGED; ANESTHESIA INDUCTION; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BREAST SURGERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; ELECTIVE SURGERY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; WOUND INFECTION;

EID: 0033925984     PISSN: 07487983     EISSN: None     Source Type: Journal    
DOI: 10.1053/ejso.1999.0899     Document Type: Article

References (15)

1. Fisher B, Bower M, Margolese R. Five-year results of a randomised clinical trial comparing mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med. 312:1985;665-673.
2. O'Dwyer P. Axillary dissection in primary breast cancer. Br Med J. 302:1991;360-361.
3. Fentiman I, Mansel R. The axilla: not a no-go zone. Lancet. 337:1991;221-222.
4. Bates T, Roberts J, Smith K, German K. A randomized trial of one versus three doses of Augmentin as wound prophylaxis in at-risk abdominal surgery. Postgrad Med J. 68:1992;811-816.
5. Palmer B, Mannur K, Ross W. An observer blind trial of co-amoxyclav versus cefuroxime plus metronidazole in the prevention of postoperative wound infection after general surgery. J Hosp Infec. 26:1994;287-292.
6. Tehan S, Lamb Y. Ciprofloxacin versus amoxycillin/clavulanic acid in the treatment of urinary tract infections in general practice. J Antimicrob Chemother. 24:1989;235-239.
7. Menzies D, Gilbert J, Shepherd M, Rogers T. A comparison between amoxycillin/clavulanate and mezlocillin in abdominal surgical prophylaxis. J Antimicrob Chemother. 24 (Suppl. B):1989;203-208.
8. Weersink A, Visser M, Vos A, Hulstaert P, ten Berge I, Muijsken M, van Vroonhoven T, Verhoef J. Amoxycillin-clavulanate prophylaxis against wound infections after clean-controlled surgery. A controlled, randomized prospective study. Eur J Surg. 157:1991;271-275.
9. Drumm J, Donovan I, Wise R, Lowe P. Metronidazole and Augmentin in the prevention of sepsis after appendicectomy. Br J Surg. 72:1985;571-573.
10. Hall C, Curran F, Burdon D, Keighley M. A randomised trail to compare amoxycillin/clavulanate with metronidazole plus gentamicin in prophylaxis in elective colorectal surgery. J Antimicrob Chemother. 24 (Suppl. B):1989;195-202.
11. Mosimann F, Cornu P, N'Ziya Z. Amoxycillin/clavulanic acid prophylaxis in elective colorectal surgery: a prospective randomized trial. J Hosp Infect. 37:1997;55-64.
12. El-Mufti M, Glessa A. A single dose clavulanate-potentiated amoxycillin versus three-dose cefotaxime in the prevention of wound infection following elective cholecystectomy: A prospective randomised study. J Int Med Res. 16:1988;92-97.
13. Krige J, Issacs S, Stapleton G, McNally J. Prospective, randomised study comparing amoxycillin-clavulanic acid and cefamandole for the prevention of wound infection in high-risk patients undergoing elective biliary surgery. J Hosp Infec. 22 (Suppl. A):1992;33-41.
14. Orozco H, Sifuentes Osornio J, Prado E, Takahashi T, Lopez Graniel C, Anaya E, Canto J. Comparison of two antimicrobial prophylaxis regimes in biliary tract surgery: a randomized controlled clinical trial. Rev Invest Clin. 45:1993;565-569.
15. Wagman L, Tegtmeier B, Beatty Jea. A prospective double-blind study of the use of antibiotics at the time of mastectomy. Surg Gyn Obs. 170:1990;12-16.