Staphylococcal display for combinatorial protein engineering of a head-to-tail affibody dimer binding the Alzheimer amyloid-β peptide

Biotechnology Journal

Volumn 8, Issue 1, 2013, Pages 139-145

  Lindberg, Hanna ^a   Johansson, Anna ^a   Härd, Torleif ^b   Ståhl, Stefan ^a   Löfblom, John ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Affibody molecules; Alzheimer's disease; Amyloid beta; Bacterial display; Combinatorial protein engineering

Indexed keywords

AFFIBODY MOLECULES; AFFINITY MATURATION; ALZHEIMER AMYLOID; ALZHEIMER'S DISEASE; AMYLOID BETAS; BINDING MECHANISMS; CELL SURFACES; COMBINATORIAL LIBRARY; DISPLAY PLATFORM; DISPLAY SYSTEM; FRUIT FLIES; FUNCTIONAL EXPRESSION; INTRAMOLECULAR DISULFIDE BONDS; N-TERMINALS; NEUROTOXICITY; PH SENSITIVITY; PROTEIN ENGINEERING; SURFACE EXPRESSION;

BINDERS; CELL MEMBRANES; COVALENT BONDS; DISPLAY DEVICES; GENETIC ENGINEERING; GLYCOPROTEINS; MOLECULES; PEPTIDES;

BIOCHEMICAL ENGINEERING;

AFFIBODY; AMYLOID BETA PROTEIN; BINDING PROTEIN; DIMER; STAPHYLOCOCCUS PROTEIN A; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CELL SURFACE; CODON; COMBINATORIAL LIBRARY; DISULFIDE BOND; FLOW CYTOMETRY; MOLECULAR CLONING; NONHUMAN; PEPTIDE LIBRARY; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STAPHYLOCOCCUS CARNOSUS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BIOTECHNOLOGY; CELL MEMBRANE; FLOW CYTOMETRY; HUMANS; MODELS, MOLECULAR; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; STAPHYLOCOCCUS;

BACTERIA (MICROORGANISMS);

EID: 84871749509     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201200228     Document Type: Article

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