Human conjunctival microvasculature assessed with a retinal function imager (RFI)

Microvascular Research

Volumn 85, Issue 1, 2013, Pages 134-137

  Jiang, Hong ^a,b   Ye, Yufeng ^a,c   DeBuc, Delia Cabrera ^a   Lam, Byron L ^a   Rundek, Tatjana ^b   Tao, Aizhu ^a   Shao, Yilei ^a,d   Wang, Jianhua ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c HANGZHOU FIRST PEOPLE'S HOSPITAL   (China)

^d WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; HEMOGLOBIN;

ADULT; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL; COMPARATIVE STUDY; CONJUNCTIVAL MICROVASCULATURE; CONTACT LENS; CONTROLLED STUDY; ERYTHROCYTE; EYE EXAMINATION; FEASIBILITY STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; IMAGE ANALYSIS; MALE; NON INVASIVE PROCEDURE; NORMAL HUMAN; PRIORITY JOURNAL; PROGNOSIS; RETINA IMAGE; VASCULAR DISEASE;

ADULT; BLOOD FLOW VELOCITY; CONJUNCTIVA; CONTACT LENSES; CONTRAST MEDIA; DISEASE PROGRESSION; ERYTHROCYTES; FEMALE; HEMOGLOBINS; HUMANS; MALE; MICROCIRCULATION; MICROVESSELS; PILOT PROJECTS; PROGNOSIS; RETINAL VESSELS; STRESS, MECHANICAL;

EID: 84871721684     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2012.10.003     Document Type: Article

References (25)

1. Beutelspacher S.C., Serbecic N., Barash H., Burgansky-Eliash Z., Grinvald A., Jonas J.B. Central serous chorioretinopathy shows reduced retinal flow circulation in retinal function imaging (RFI). Acta Ophthalmol. 2011, 89:e479-e482.
2. Cheung A.T., Perez R.V., Basadonna G.P., Cox K.L., Bry W.I. Microangiopathy reversal in successful simultaneous pancreas-kidney transplantation. Transplant. Proc. 1994, 26:493-495.
3. Cheung A.T., Chen P.C., Leshchinsky T.V., Wiltse S.L., Basadonna G.P., Katznelson S., Perez R.V. Improvement in conjunctival microangiopathy after simultaneous pancreas-kidney transplants. Transplant. Proc. 1997, 29:660-661.
4. Cheung A.T., Perez R.V., Chen P.C. Improvements in diabetic microangiopathy after successful simultaneous pancreas-kidney transplantation: a computer-assisted intravital microscopy study on the conjunctival microcirculation. Transplantation 1999, 68:927-932.
5. Cheung A.T., Harmatz P., Wun T., Chen P.C., Larkin E.C., Adams R.J., Vichinsky E.P. Correlation of abnormal intracranial vessel velocity, measured by transcranial Doppler ultrasonography, with abnormal conjunctival vessel velocity, measured by computer-assisted intravital microscopy, in sickle cell disease. Blood 2001, 97:3401-3404.
6. Cheung A.T., Ramanujam S., Greer D.A., Kumagai L.F., Aoki T.T. Microvascular abnormalities in the bulbar conjunctiva of patients with type 2 diabetes mellitus. Endocr. Pract. 2001, 7:358-363.
7. Cheung A.T., Chen P.C., Larkin E.C., Duong P.L., Ramanujam S., Tablin F., Wun T. Microvascular abnormalities in sickle cell disease: a computer-assisted intravital microscopy study. Blood 2002, 99:3999-4005.
8. Cheung A.T., Price A.R., Duong P.L., Ramanujam S., Gut J., Larkin E.C., Chen P.C., Wilson D.M. Microvascular abnormalities in pediatric diabetic patients. Microvasc. Res. 2002, 63:252-258.
9. Cheung A.T., Chan M.S., Ramanujam S., Rangaswami A., Curl K., Franklin P., Wun T. Effects of poloxamer 188 treatment on sickle cell vaso-occlusive crisis: computer-assisted intravital microscopy study. J. Investig. Med. 2004, 52:402-406.
10. Cheung A.T., Hu B.S., Wong S.A., Chow J., Chan M.S., To W.J., Li J., Ramanujam S., Chen P.C. Microvascular abnormalities in the bulbar conjunctiva of contact lens users. Clin. Hemorheol. Microcirc. 2012, 51:77-86.
11. Duench S., Simpson T., Jones L.W., Flanagan J.G., Fonn D. Assessment of variation in bulbar conjunctival redness, temperature, and blood flow. Optom. Vis. Sci. 2007, 84:511-516.
12. Duke-Elder S. System of Ophthalmology 1961, CV Mosby, St. Louis.
13. Fonn D., MacDonald K.E., Richter D., Pritchard N. The ocular response to extended wear of a high Dk silicone hydrogel contact lens. Clin. Exp. Optom. 2002, 85:176-182.
14. Izhaky D., Nelson D.A., Burgansky-Eliash Z., Grinvald A. Functional imaging using the retinal function imager: direct imaging of blood velocity, achieving fluorescein angiography-like images without any contrast agent, qualitative oximetry, and functional metabolic signals. Jpn. J. Ophthalmol. 2009, 53:345-351.
15. Koutsiaris A.G., Tachmitzi S.V., Batis N., Kotoula M.G., Karabatsas C.H., Tsironi E., Chatzoulis D.Z. Volume flow and wall shear stress quantification in the human conjunctival capillaries and post-capillary venules in vivo. Biorheology 2007, 44:375-386.
16. Koutsiaris A.G., Tachmitzi S.V., Papavasileiou P., Batis N., Kotoula M.G., Giannoukas A.D., Tsironi E. Blood velocity pulse quantification in the human conjunctival pre-capillary arterioles. Microvasc. Res. 2010, 80:202-208.
17. Landa G., Rosen R.B. A new vascular pattern for idiopathic juxtafoveal telangiectasia revealed by the retinal function imager. Ophthalmic Surg. Lasers Imaging 2010, 41:413-417.
18. Landa G., Jangi A.A., Garcia P.M., Rosen R.B. Initial report of quantification of retinal blood flow velocity in normal human subjects using the Retinal Functional Imager (RFI). Int. Ophthalmol. 2012, 32:211-215.
19. Nelson D.A., Krupsky S., Pollack A., Aloni E., Belkin M., Vanzetta I., Rosner M., Grinvald A. Special report: noninvasive multi-parameter functional optical imaging of the eye. Ophthalmic Surg. Lasers Imaging 2005, 36:57-66.
20. Nelson D.A., Burgansky-Eliash Z., Barash H., Loewenstein A., Barak A., Bartov E., Rock T., Grinvald A. High-resolution wide-field imaging of perfused capillaries without the use of contrast agent. Clin. Ophthalmol. 2011, 5:1095-1106.
21. Ohtani N. Laser Doppler flowmetry of the bulbar conjunctiva as a monitor of the cerebral blood flow. Invest. Ophthalmol. Vis. Sci. 1996, 44:1721-1728.
22. Schaser K.D., Settmacher U., Puhl G., Zhang L., Mittlmeier T., Stover J.F., Vollmar B., Menger M.D., Neuhaus P., Haas N.P. Noninvasive analysis of conjunctival microcirculation during carotid artery surgery reveals microvascular evidence of collateral compensation and stenosis-dependent adaptation. J. Vasc. Surg. 2003, 37:789-797.
23. Shahidi M., Wanek J., Gaynes B., Wu T. Quantitative assessment of conjunctival microvascular circulation of the human eye. Microvasc. Res. 2010, 79:109-113.
24. Shen M., Cui L., Riley C., Wang M.R., Wang J. Characterization of soft contact lens edge fitting using ultra-high resolution and ultra-long scan depth optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2011, 52:4091-4097.
25. To W.J., Telander D.G., Lloyd M.E., Chen P.C., Cheung A.T. Correlation of conjunctival microangiopathy with retinopathy in type-2 diabetes mellitus (T2DM) patients. Clin. Hemorheol. Microcirc. 2011, 47:131-141.