Human herpesvirus 8 (HHV8) transmission and related morbidity in organ recipients

American Journal of Transplantation

Volumn 13, Issue 1, 2013, Pages 207-213

  Lebbe, C ^a   Porcher, R ^a   Marcelin, A G ^b   Agbalika, F ^b   Dussaix, E ^c   Samuel, D ^d   Varnous, S ^b   Euvrard, S ^e   Bigorie, A ^f   Creusvaux, H ^f   Legendre, C ^a   Frances, C ^b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d HÔPITAL PAUL BROUSSE   (France)

^e EDOUARD HERRIOT HOSPITAL   (France)

^f Agence de BioMédecine   (France)

Author keywords

Kaposi's sarcoma; organ transplantation; transmission; type 8 human herpes virus

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN A; LYMPHOCYTE ANTIBODY; MYCOPHENOLIC ACID; RAPAMYCIN; RITUXIMAB; TACROLIMUS;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CARDIAC GRAFT REJECTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; GRAFT RECIPIENT; HEART GRAFT; HEART TRANSPLANTATION; HEMOPHAGOCYTIC SYNDROME; HUMAN; HUMAN HERPESVIRUS 8; IMMUNOFLUORESCENCE; IMMUNOSUPPRESSIVE TREATMENT; KAPOSI SARCOMA; KIDNEY GRAFT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVER GRAFT; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MULTICENTER STUDY; ORGAN DONOR; PRIORITY JOURNAL; SEROCONVERSION; SEROPREVALENCE; VIRUS TRANSMISSION;

ADULT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; MALE; MIDDLE AGED; ORGAN TRANSPLANTATION; TISSUE DONORS; VIREMIA;

EID: 84871712002     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2012.04290.x     Document Type: Article

References (15)

1. Frances C, Marcelin AG, Legendre C, et al.. The impact of preexisting or acquired Kaposi sarcoma herpesvirus infection in kidney transplant recipients on morbidity and survival. Am J Transplant 2009; 9: 2580-2586.
2. Corchero JL, Mar EC, Spira TJ, Pellett PE, Inoue N,. Comparison of serologic assays for detection of antibodies against human herpesvirus 8. Clin Diagnos Lab Immunol 2001; 8: 913-921.
3. Laney AS, Peters JS, Manzi SM, Kingsley LA, Chang Y, Moore PS,. Use of a multiantigen detection algorithm for diagnosis of Kaposi's sarcoma-associated herpesvirus infection. J Clin Microbiol 2006; 44: 3734-3741.
4. Simpson GR, Schulz TF, Whitby D, et al.. Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 1996; 348: 1133-1138.
5. Nascimento MC, de Souza VA, Sumita LM, et al.. Comparative study of Kaposi's sarcoma-associated herpesvirus serological assays using clinically and serologically defined reference standards and latent class analysis. J Clin Microbiol 2007; 45: 715-720.
6. Plancoulaine S, Abel L, van Beveren M, Gessain A,. High titers of anti-human herpesvirus 8 antibodies in elderly males in an endemic population. J Natl Cancer Inst 2002; 94: 1333-1335.
7. Lambert M, Gannage M, Karras A, et al.. Differences in the frequency and function of HHV8-specific CD8 T cells between asymptomatic HHV8 infection and Kaposi sarcoma. Blood 2006; 108: 3871-3880.
8. Pietrosi G, Vizzini G, Pipitone L, et al.. Primary and reactivated HHV8 infection and disease after liver transplantation: A prospective study. Am J Transplant 2011; 11: 2715-2723.
9. Thaunat O, Mamzer-Bruneel MF, Agbalika F, et al.. Severe human herpesvirus-8 primary infection in a renal transplant patient successfully treated with anti-CD20 monoclonal antibody. Blood 2006; 107: 3009-3010.
10. Duchini A, Goss JA, Karpen S, Pockros PJ,. Vaccinations for adult solid-organ transplant recipients: Current recommendations and protocols. Clin Microbiol Rev 2003; 16: 357-364.
11. Biggar RJ, Engels EA, Whitby D, Kedes DH, Goedert JJ,. Antibody reactivity to latent and lytic antigens to human herpesvirus-8 in longitudinally followed homosexual men. J Infect Dis 2003; 187: 12-18.
12. Sullivan CS,. High conservation of Kaposi sarcoma-associated herpesvirus microRNAs implies important function. J Infect Dis 2007; 195: 618-620.
13. Zavitsanou A, Sypsa V, Petrodaskalaki M, et al.. Human herpesvirus 8 infection in hemodialysis patients. Am J Kidney Dis 2006; 47: 167-170.
14. Bohl DL, Brennan DC, Ryschkewitsch C, Gaudreault-Keener M, Major EO, Storch GA,. BK virus antibody titers and intensity of infections after renal transplantation. J Clin Virol 2008; 43: 184-189.
15. Humar A, Limaye AP, Blumberg EA, et al.. Extended valganciclovir prophylaxis in D+/R- kidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: Two-year results of the IMPACT study. Transplantation 2010; 90: 1427-1431.