The impact of preexisting or acquired kaposi sarcoma herpesvirus infection in kidney transplant recipients on morbidity and survival

American Journal of Transplantation

Volumn 9, Issue 11, 2009, Pages 2580-2586

  Frances C ^a   Marcelin, A G ^b   Legendre, Ch ^c   Chevret, S ^d   Dussaix, E ^e   Lejeune, J ^d   Euvrard, S ^f   Bigorie, A ^g   Schulz, T F ^h   Agbalika, F ⁱ   Lebbe C ^d  

^a HÔPITAL TENON   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d SAINT LOUIS HOSPITAL   (France)

^e HÔPITAL PAUL BROUSSE   (France)

^f EDOUARD HERRIOT HOSPITAL   (France)

^g Direction médicale et scientifique Agence de la biomédecine   (France)

^h HANNOVER MEDICAL SCHOOL   (Germany)

ⁱ Department of Microbiology ^*

Author keywords

Human herpesvirus type 8; Kaposi sarcoma herpesvirus; Kaposi's sarcoma; Kidney transplantation

Indexed keywords

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL EVALUATION; CLINICAL FEATURE; DISEASE ASSOCIATION; FEMALE; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HERPES VIRUS INFECTION; HUMAN; KAPOSI SARCOMA; KIDNEY DONOR; KIDNEY GRAFT; KIDNEY INFECTION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; SEROLOGY; VIREMIA;

AFRICAN CONTINENTAL ANCESTRY GROUP; ANTIBODIES, VIRAL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; FRANCE; GRAFT SURVIVAL; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MORBIDITY; PROSPECTIVE STUDIES; RISK FACTORS; SEROEPIDEMIOLOGIC STUDIES; SURVIVAL ANALYSIS;

EID: 70350134984     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2009.02816.x     Document Type: Article

References (31)

1. Luppi M, Barozzi P, Santagostino G et al. Molecular evidence of organ-related transmission of Kaposi sarcoma-associated herpesvirus or human herpesvirus-8 in transplant patients. Blood 2000 96 : 3279 3281.
2. Marcelin AG, Calvez V, Dussaix E. KSHV after an organ transplant: Should we screen? Curr Top Microbiol Immunol 2007 312 : 245 262.
3. Regamey N, Tamm M, Wernli M et al. Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients. N Engl J Med 1998 339 : 1358 1363.
4. Milliancourt C, Barete S, Marcelin AG et al. Human herpesvirus-8 seroconversions after renal transplantation. Transplantation 2001 72 : 1319 1320.
5. Sheldon J, Henry S, Mourad M et al. Human herpes virus 8 infection in kidney transplant patients in Belgium. Nephrol Dial Transplant 2000 15 : 1443 1445.
6. Francès C, Mouquet C, Marcelin AG et al. Outcome of kidney transplant recipients with previous human herpesvirus 8 infection. Transplantation 2000 69 : 1776 1779.
7. Cattani P, Capuano M, Graffeo R et al. Kaposi's sarcoma associated with previous human herpesvirus 8 infection in kidney transplant recipients. J Clin Microbiol 2001 39 : 506 508.
8. Simpson GR, Schulz TF, Whitby D et al. Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid proteins and latent immunofluorescence antigen. Lancet 1996 349 : 1133 1138.
9. Engels EA, Sinclair MD, Biggar RJ et al. Latent class analysis of human herpesvirus 8 assay performance and infection prevalence in sub-Saharan Africa and Malta. Int J Cancer 2000 88 : 1003 1008.
10. Oksenhendler E, Carcelain G, Aoki Y et al. High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients. Blood 2000 96 : 2069 2079.
11. Deback C, Agbalika F, Scieux C et al. Detection of human herpesviruses HHV-6, HHV-7 and HHV-8 in whole blood by real-time PCR using the new CMV, HHV-6, 7, 8 R-gene trademark kit. J Virol Methods 2008 149 : 285 291.
12. Gray RJ. A class of K-sample tests for comparing the cumulative incidence of a competing risk. The Annals of Statistics 1988 16 : 1141 1154.
13. Fine JP, Gray RJ. A proportional hazards model for subdistribution of a competing risk. Journal of the American Statistical Association 1999 94 : 496 509.
14. Thaunat O, Mamzer-Bruneel MF, Agbalika F et al. Severe human herpesvirus-8 primary infection in a renal transplant patient successfully treated with anti-CD20 monoclonal antibody. Blood 2006 107 : 3009 3010.
15. Schulz TF. Epidemiology of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. Adv Cancer Res 1999 76 : 121 160.
16. Marcelin AG, Dupin N, Bossi P, Calvez V. Seroprevalence of human herpesvirus-8 in healthy subjects and patients with AIDS-associated and classical Kaposi's sarcoma in France. AIDS 1998 12 : 539 540.
17. Challine D, Roudot-Thoraval F, Sarah T et al. Seroprevalence of human herpes virus 8 antibody in populations at high or low risk of transfusion, graft, or sexual transmission of viruses. Transfusion 2001 41 : 1120 1125.
18. Dollard SC, Nelson KE, Ness PM et al. Possible transmission of human herpesvirus-8 by blood transfusion in a historical United States cohort. Transfusion 2005 45 : 500 503.
19. Francès C. Kaposi's sarcoma after renal transplantation. Nephrol Dial Transplant 1998 13 : 2768 2773.
20. Serraino D, Angeletti C, Carrieri MP et al. Kaposi's sarcoma in transplant and HIV-infected patients: an epidemiologic study in Italy and France. Transplantation 2005 80 : 1699 16704.
21. Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med 2003 348 : 1681 1691.
22. Alkharsah KR, Dedicoat M, Blasczyk R, Newton R, Schulz TF. Influence of HLA alleles on shedding of Kaposi sarcoma-associated herpesvirus in saliva in an African population. J Infect Dis 2007 195 : 809 816.
23. Stallone G, Infante B, Grandaliano G, Schena FP, Gesualdo L. Kaposi's sarcoma and mTOR: A crossroad between viral infection neoangiogenesis and immunosuppression. Transpl Int 2008 21 : 825 832.
24. Di Benedetto F, Di Sandro S, De Ruvo N et al. Kaposi's sarcoma after liver transplantation. J Cancer Res Clin Oncol 2008 134 : 653 658.
25. Lebbé C, Euvrard S, Barrou B et al. Sirolimus conversion for patients with posttransplant Kaposi's sarcoma. Am J Transplant 2006 6 : 2164 2168.
26. Luppi M, Barozzi P, Rasini V et al. Severe pancytopenia and hemophagocytosis after HHV-8 primary infection in a renal transplant patient successfully treated with foscarnet. Transplantation 2002 74 : 131 132.
27. Luppi M, Barozzi P, Guaraldi G et al. Human herpesvirus 8-associated diseases in solid-organ transplantation: Importance of viral transmission from the donor. Clin Infect Dis 2003 37 : 606 607.
28. Luppi M, Barozzi P, Schulz TF et al. Bone marrow failure associated with human herpesvirus 8 infection after transplantation. N Engl J Med 2000 343 : 1378 1385.
29. Re A, Facchetti F, Borlenghi E et al. Fatal hemophagocytic syndrome related to active human herpesvirus-8/Kaposi sarcoma-associated herpesvirus infection in human immunodeficiency virus-negative, non-transplant patients without related malignancies. Eur J Haematol 2007 78 : 361 364.
30. Barete S, Calvez V, Mouquet C et al. Clinical features and contribution of virological findings to the management of Kaposi sarcoma in organ-allograft recipients. Arch Dermatol 2000 136 : 1452 1458.
31. Schatz O, Monini P, Bugarini R et al. Kaposi's sarcoma-associated herpesvirus serology in Europe and Uganda: Multicentre study with multiple and novel assays. J Med Virol 2001 65 : 123 132.