Carcinogenesis: UV radiation

Textbook of Aging Skin

Volumn , Issue , 2010, Pages 567-578

  Brash, Douglas E ^a   Heffernan, Timothy P ^a   Nghiem, Paul ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84871699972     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-540-89656-2_56     Document Type: Chapter

References (36)

1. Leigh I, Newton-Bishop JA, Kripke ML. Skin Cancer. Plainview: Cold Spring Harbor Laboratory Press, 1996, pp. 361, Cancer Surveys, vol. 26.
2. Brash DE, Pontén J. Skin precancer. In: Pontén J (ed) Precancer: Biology, Importance, and Possible Prevention. Cold Spring Harbor: Cold Spring Harbor Press, 1998, pp. 69-113.
3. Brash DE. Sunlight and the onset of skin cancer. Trends Genet. 1997; 13:410-414.
4. de Gruijl FR, Ananthaswamy HN. Biological effects of ultraviolet radiation. Mutat Res. 2005;571(special issue).
5. Hussein MR. Ultraviolet radiation and skin cancer: Molecular mechanisms. J Cutan Pathol. 2005;32(3):191-205.
6. Latonen L, Laiho M. Cellular UV damage responses-functions of tumor suppressor p53. Biochim Biophys Acta. 2005;1755:71-89.
7. Raj D, Brash DE, Grossman D. Keratinocyte apoptosis in epidermal development and disease. J Invest Dermatol. 2006;126:243-257.
8. Green A, MacLennan R, Youl P, Martin N. Site distribution of cutaneous melanoma in Queensland. Int J Cancer. 1993;53:232-236.
9. Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Brocker EB, LeBoit PE, Pinkel D, Bastian BC. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353(20):2135-2147.
10. Landi MT, Bauer J, Pfeiffer RM, Elder DE, Hulley B, Minghetti P, Calista D, Kanetsky PA, Pinkel D, Bastian BC. MC1R germline variants confer risk for BRAF-mutant melanoma. Science. 2006; 313(5786):521-522.
11. Kollias N, Sayre RM, Zeise L, Chedekel MR. Photoprotection by melanin. J Photochem Photobiol B. 1991;9(2):135-160.
12. Freeman SE, Hacham H, Gange RW, Maytum DJ, Sutherland JC. Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light. Proc Natl Acad Sci USA. 1989;86:5605-5609.
13. Gallagher RP, Spinelli JJ, Lee TK. Tanning beds, sunlamps, and risk of cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev. 2005;14(3):562-566.
14. Wang SY. Photochemistry and Photobiology of Nucleic Acids. New York: Academic, 1976, 596 pp., vol. I.
15. Douki T, Reynaud-Angelin A, Cadet J, Sage E. Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation. Biochemistry. 2003;42(30):9221-9226.
16. Cleaver JE. Cancer in xeroderma pigmentosum and related disorders of DNA repair. Nat Rev Cancer. 2005;5(7):564-573.
17. Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Pontén J. A.role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA. 1991;88:10124-10128.
18. Tornaletti S, Pfeifer GP. Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science. 1994;263:1436-1438.
19. Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T, Brash DE. Sunburn and p53 in the onset of skin cancer. Nature. 1994;372:773-776.
20. Jonason AS, Kunala S, Price GJ, Restifo RJ, Spinelli HM, Persing JA, Leffell DJ, Tarone RE, Brash DE. Frequent clones of p53-mutated keratinocytes in normal human skin. Proc Natl Acad Sci USA. 1996;93:14025-14029.
21. Gailani MR, Bale SJ, Leffell DJ, DiGiovanna JJ, Peck GL, Poliak S, Drum MA, Pastakia B, McBride OW, Kase R, Greene M, Mulvihill JJ, Bale AE. Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9. Cell. 1992;69: 111-117.
22. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA. Mutations of the BRAF gene in human cancer. Nature. 2002;417(6892):949-954.
23. Bender K, Blattner C, Knebel A, Iordanov M, Herrlich P, Rahmsdorf HJ. UV-induced signal transduction. J Photochem Photobiol B. 1997;37:1-17.
24. Tonks NK. Redox redux: Revisiting PTPs and the control of cell signaling. Cell. 2005;121:667-670.
25. Devary Y, Rosette C, DiDonato JA, Karin M. NF-kB activation by ultraviolet light not dependent on a nuclear signal. Science. 1993;261:1442-1445.
26. Schwarz A, Stander S, Berneburg M, Bohm M, Kulms D, Van Steeg H, Grosse-Heitmeyer K, Krutmann J, Schwarz T. Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair. Nat Cell Biol. 2002;4:26-31.
27. Fisher GJ, Datta SC, Talwar HS, Wang ZQ, Varani J, Kang S, Voorhees JJ. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature. 1996;379:335-339.
28. Hill LL, Ouhtit A, Loughlin SM, Kripke ML, Ananthaswamy HN, Owen-Schaub LB. Fas ligand: A sensor for DNA damage critical in skin cancer etiology. Science. 1999;285:898-900.
29. Levy V, Lindon C, Harfe BD, Morgan BA. Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell. 2005;9(6):855-861.
30. Oro AE, Higgins KM, Hu Z, Bonifas JM, Epstein EH, Scott MP. Basal cell carcinomas in mice overexpressing sonic hedgehog. Science. 1997;276:817-821.
31. Zhang W, Remenyik E, Zelterman D, Brash DE, Wikonkal NM. Escaping the stem cell compartment: Sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations. Proc Natl Acad Sci USA. 2001;98:13948-13953.
32. Mudgil AV, Segal N, Andriani F, Wang Y, Fusenig NE, Garlick JA. Ultraviolet-B irradiation induces expansion of intraepithelial tumor cells in a tissue model of early cancer progression. J Invest Dermatol. 2003;121:191-197.
33. Jans J, Schul W, Sert YG, Rijksen Y, Rebel H, Eker AP, Nakajima S, Van Steeg H, De Gruijl FR, Yasui A, Hoeijmakers JH, Van Der Horst GT. Powerful skin cancer protection by a CPD-photolyase transgene. Curr Biol. 2005;15(2):105-115.
34. Moodycliffe AM, Nghiem D, Clydesdale G, Ullrich SE. Immune suppression and skin cancer development: Regulation by NKT cells. Nat Immunol. 2000;1(6):521-525.
35. Takeuchi S, Zhang W, Wakamatsu K, Ito S, Hearing V, Kraemer KH, Brash DE. Melanin acts as a potent UVB sensitizer to cause an atypical mode of cell death in murine skin. Proc Natl Acad Sci USA. 2004;101:15076-15081.
36. Ramsay HM, Harden PN, Reece S, Smith AG, Jones PW, Strange RC, Fryer AA. Polymorphisms in glutathione S-transferases are associated with altered risk of nonmelanoma skin cancer in renal transplant recipients: A preliminary analysis. J Invest Dermatol. 2001;117: 251-255.