Hydrophobic amino acids in the hinge region of the 5A apolipoprotein mimetic peptide are essential for promoting cholesterol efflux by the ABCA1 transporter

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 1, 2013, Pages 50-58

  Sviridov, Denis O ^a   Andrianov, Alexander M ^b   Anishchenko, Ivan V ^c   Stonik, John A ^a   Amar, Marcelo J A ^a   Turner, Scott ^d   Remaley, Alan T ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

^c INSTITUTE FOR MATHEMATICS   (Belarus)

^d KINEMED INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A5 MIMETIC PEPTIDE; CHOLESTEROL; PEPTIDE DERIVATIVE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FEMALE; MACROPHAGE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SOLUBILIZATION; STRUCTURE ANALYSIS; TRIACYLGLYCEROL BLOOD LEVEL;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; APOLIPOPROTEINS A; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CHOLESTEROL; CIRCULAR DICHROISM; CRICETINAE; FEMALE; LIPIDS; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PHOSPHOLIPIDS;

EID: 84871694179     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.198143     Document Type: Article

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