Liquid chromatography-tandem mass spectrometry approach for quantification of mucins from sputum using 13C,15N-labeled peptides as internal standards

Analytical Biochemistry

Volumn 434, Issue 1, 2013, Pages 84-92

  Lindberg, Claes ^a   Van Geest, Marleen ^a   Lindberg, Henrik ^a   Kjellström, Sven ^a,b  

^a ASTRAZENECA R AND D   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Mass spectrometry; Mucins; Sputum

Indexed keywords

AMINO ACIDS; LIQUIDS; MASS SPECTROMETRY; PEPTIDES; PHASE SEPARATION;

ACCURATE QUANTIFICATIONS; CYSTEINE-CONTAINING PEPTIDES; LINEAR CALIBRATION CURVE; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY (LC MS/MS); LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MUCINS; SELECTED REACTION MONITORING; SPUTUM;

LIQUID CHROMATOGRAPHY;

CARBON 13; CYSTEINE; MUCIN; MUCIN 5AC; MUCIN 5B; NITROGEN 15; STABLE ISOTOPE; SYNTHETIC PEPTIDE; TRYPSIN;

ACCURACY; ADSORPTION; ALKYLATION; AMINO ACID SEQUENCE; ARTICLE; CALIBRATION; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; FREEZE THAWING; ISOTOPE LABELING; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; REDUCTION; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; SOLUBILIZATION; SPUTUM; SPUTUM ANALYSIS; STANDARD; TANDEM MASS SPECTROMETRY;

EID: 84871693834     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.10.033     Document Type: Article

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