Characteristic gene expression profiles in the progression from normal gastric epithelial cells to moderate gastric epithelial dysplasia and to gastric cancer

Chinese Medical Journal

Volumn 125, Issue 10, 2012, Pages 1777-1783

  Li, Mao Lan ^a   Zhang, Jing Cheng ^b   Li, Song Gang ^a   Wu, Wen Guang ^a   Rao, Long Hua ^a   Dong, Ping ^a   Gu, Jun ^a   Lu, Jian Hua ^a   Zhang, Lin ^a   Ding, Qi Chen ^a   Wu, Xiang Song ^a   Mu, Jia Sheng ^a   Yang, Jia Hua ^a   Zhang, Wen Jie ^a   Chen, Lei ^a   Liu, Ying Bin ^a  

^a XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Dysplasia; Gastric cancer; Gene chips technology

Indexed keywords

CASPASE 14; CHITINASE; CXCL1 CHEMOKINE; LEUKEMIA INHIBITORY FACTOR; MACROPHAGE ELASTASE; MANGANESE SUPEROXIDE DISMUTASE; POTASSIUM CHANNEL KCNE2; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; TRANSCRIPTION FACTOR MSX1; WNT3 PROTEIN; TRANSCRIPTOME;

ADULT; ARTICLE; CELL ADHESION; CELL DEATH; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA MICROARRAY; DOWN REGULATION; FEMALE; GASTROINTESTINAL DYSPLASIA; GASTROSCOPY; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; MALE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH EPITHELIUM; UPREGULATION; AGED; EPITHELIUM CELL; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; STOMACH; STOMACH MUCOSA; STOMACH TUMOR;

ADULT; AGED; EPITHELIAL CELLS; GASTRIC MUCOSA; HUMANS; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH; STOMACH NEOPLASMS; TRANSCRIPTOME;

EID: 84871692397     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.10.017     Document Type: Article

References (38)

1. Sun XD, Mu R, Zhou YS, Dai XD, Zhang SW, Huang XM, et al. Analysis of mortality rate of stomach cancer and its trend in twenty years in China. Chin J Oncol (Chin) 2004; 26: 4-9.
2. Bornschein J, Kandulski A, Selgrad M, Malfertheiner P. From gastric inflammation to gastric cancer. Dig Dis 2010; 28: 609-614.
3. Fox JG, Wang TC. Inflammation, atrophy, and gastric cancer. J Clin Invest 2007; 117: 60-69.
4. Micev M, Cosić-Micev M. Pathology and pathobiology of the gastric carcinoma. Acta Chir Iugosl 2011; 58: 39-52.
5. Bittoni A, Maccaroni E, Scartozzi M, Berardi R, Cascinu S. Chemotherapy for locally advanced and metastatic gastric cancer: state of the art and future perspectives. Eur Rev Med Pharmacol Sci 2010; 14: 309-314.
6. Greenlee RT, Hill-Harmon MB, Murray T, Thun M. Cancer statistics, 2001. CA Cancer J Clin 2001; 51: 15-36.
7. Guo T, Lee SS, Ng WH, Zhu Y, Gan CS, Zhu J, et al. Global molecular dysfunctions in gastric cancer revealed by an integrated analysis of the phosphoproteome and transcriptome. Cell Mol Life Sci 2011; 68: 1983-2002.
8. Dicken BJ, Bigam DL, Cass C, Mackey JR, Joy AA, Hamilton SM. Gastric adenocarcinoma: review and considerations for future directions. Ann Surg 2005; 241: 27-39.
9. Goonetilleke KS, Siriwardena AK. Current status of gene expression profiling of pancreatic cancer. Int J Surg 2008; 6: 81-83.
10. Kim H, Eun JW, Lee H, Nam SW, Rhee H, Koh KH, et al. Gene expression changes in patient-matched gastric normal mucosa, adenomas, and carcinomas. Exp Mol Pathol 2011; 90: 201-209.
11. Svrcek M. High-grade gastric intra-epithelial neoplasia (or dysplasia) treated by endoscopic mucosal resection. Ann Pathol 2011; 31: 375-380.
12. Jang BG, Kim WH. Molecular pathology of gastric carcinoma. Pathobiology 2011; 78: 302-310.
13. Liu J, Chen L. Current status and progress in gastric cancer with liver metastasis. Chin Med J 2011; 124: 445-456.
14. Kim JJ, Chae SW, Hur GC, Cho SJ, Kim MK, Choi J, et al. Manganese superoxide dismutase expression correlates with a poor prognosis in gastric cancer. Pathobiology 2002-2003; 70: 353-360.
15. Cheng P, Jiang FH, Zhao LM, Dai Q, Yang WY, Zhu LM, et al. Human macrophage metalloelastase correlates with angiogenesis and prognosis of gastric carcinoma. Dig Dis Sci 2010; 55: 3138-3146.
16. Takada H, Imoto I, Tsuda H, Nakanishi Y, Sakakura C, Mitsufuji S, et al. Genomic loss and epigenetic silencing of very-low-density lipoprotein receptor involved in gastric carcinogenesis. Oncogene 2006; 25: 6554-6562.
17. Liu S, Sun LP, Yuan Y. Clinacal significancance of serum cellular fibronectin concentrations in gastric cancer and precancerous diseases of stomach. Chin J Clin Oncol (Chin) 2006; 33: 194-197.
18. Jung JJ, Noh S, Jeung HC, Jung M, Kim TS, Noh SH, et al. Chemokine growth-regulated oncogene 1 as a putative biomarker for gastric cancer progression. Cancer Sci 2010; 101: 2200-2206.
19. Roepke TK, Purtell K, King EC, La Perle KM, Lerner DJ, Abbott GW. Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia. PLoS One 2010; 5: e11451-e11461.
20. Chen SH, Lin CY, Lee LT, Chang GD, Lee PP, Hung CC, et al. Up-regulation of fibronectin and tissue transglutaminase promotes cell invasion involving increased association with integrin and MMP expression in A431 cells. Anticancer Res 2010; 30: 4177-4186.
21. Parr C, Sanders AJ, Davies G, Martin T, Lane J, Mason MD, et al. Matriptase-2 inhibits breast tumor growth and invasion and correlates with favorable prognosis for breast cancer patients. Clin Cancer Res 2007; 13: 3568-3576.
22. Diefenbach CS, Shah Z, Iasonos A, Barakat RR, Levine DA, Aghajanian C, et al. Preoperative serum YKL-40 is a marker for detection and prognosis of endometrial cancer. Gynecol Oncol 2007; 104: 435-442.
23. Holen I, Cross SS, Neville-Webbe HL, Cross NA, Balasubramanian SP, Croucher PI, et al. Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo--a role in tumour cell survival? Breast Cancer Res Treat 2005; 92: 207-215.
24. Cheng XG, Ye W, Zou Q, Chen W, Jin H, Xu Y, et al. The effect of siRNA vetor inhibiting Fn14 expression on hepatoma cell proliferation. J Mlitary Surgeon Southwest China (Chin) 2008; 10: 7-9.
25. Okamura Y, Nomoto S, Kanda M, Li QY, Nishikawa Y, Sugimoto H, et al. Leukemia inhibitory factor receptor (LIFR) is detected as a novel suppressor gene of hepatocellular carcinoma using double-combination array. Cancer Lett 2010; 289: 170-177.
26. García-Tuñón I, Ricote M, Ruiz A, Fraile B, Paniagua R, Royuela M. OSM, LIF, its receptors, and its relationship with the malignance in human breast carcinoma (in situ and in infiltrative). Cancer Invest 2008; 26: 222-229.
27. Kim M, Lee HC, Tsedensodnom O, Hartley R, Lim YS, Yu E, et al. Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells. J Hepatol 2008; 48: 780-791.
28. Ray R, Cabal-Manzano R, Moser AR, Waldman T, Zipper LM, Aigner A, et al. Up-regulation of fibroblast growth factor-binding protein, by beta-catenin during colon carcinogenesis. Cancer Res 2003; 63: 8085-8089.
29. Gelderman KA, Tomlinson S, Ross GD, Gorter A. Complement function in mAb-mediated cancer immunotherapy. Trends Immunol 2004; 25: 158-164.
30. Scanlan MJ, Gout I, Gordon CM, Williamson B, Stockert E, Gure AO, et al. Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. Cancer Immun 2001; 1: 4.
31. Das S, Hahn Y, Nagata S, Willingham MC, Bera TK, Lee B, et al. NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells. Cancer Res 2007; 67: 1594-1601.
32. Carboni GL, Gao B, Nishizaki M, Xu K, Minna JD, Roth JA, et al. CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity. Oncogene 2003; 22: 615-626.
33. Li X, Feng P, Ou J, Luo Z, Dai P, Wei D, et al. Dermatopontin is expressed in human liver and is downregulated in hepatocellular carcinoma. Biochemistry (Mosc) 2009; 74: 979-985.
34. Park K, Kim K, Rho SB, Choi K, Kim D, Oh SH, et al. Homeobox Msx1 interacts with p53 tumor suppressor and inhibits tumor growth by inducing apoptosis. Cancer Res 2005; 65: 749-757.
35. Dai H, Zhang L, Cao M, Song F, Zheng H, Zhu X, et al. The role of polymorphisms in circadian pathway genes in breast tumorigenesis. Breast Cancer Res Treat 2011; 127: 531-540.
36. Wang F, Li X, Xie X, Zhao L, Chen W UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion. FEBS Lett 2008; 582: 1919-1927.
37. Drozak J, Veiga-da-Cunha M, Vertommen D, Stroobant V, Van Schaftingen E. Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1). J Biol Chem 2010; 285: 9346-9356.
38. Dias-Gunasekara S, Gubbens J, van Lith M, Dunne C, Williams JA, Kataky R, et al. Tissue-specific expression and dimerization of the endoplasmic reticulum oxidoreductase Ero1beta. J Biol Chem 2005; 280: 33066-33075.